Venetoclax enhances T cell–mediated antileukemic activity by increasing ROS production JB Lee, DH Khan, R Hurren, M Xu, Y Na, H Kang, S Mirali, X Wang, ... Blood, The Journal of the American Society of Hematology 138 (3), 234-245, 2021 | 99 | 2021 |
Allogeneic human double negative T cells as a novel immunotherapy for acute myeloid leukemia and its underlying mechanisms JB Lee, MD Minden, WC Chen, E Streck, B Chen, H Kang, A Arruda, D Ly, ... Clinical cancer research 24 (2), 370-382, 2018 | 77 | 2018 |
Human double negative T cells target lung cancer via ligand-dependent mechanisms that can be enhanced by IL-15 J Yao, D Ly, D Dervovic, L Fang, JB Lee, H Kang, YH Wang, NA Pham, ... Journal for ImmunoTherapy of Cancer 7, 1-14, 2019 | 55 | 2019 |
Targeting chemotherapy-resistant leukemia by combining DNT cellular therapy with conventional chemotherapy B Chen, JB Lee, H Kang, MD Minden, L Zhang Journal of experimental & clinical cancer research 37, 1-11, 2018 | 55 | 2018 |
Targeting late-stage non-small cell lung cancer with a combination of DNT cellular therapy and PD-1 checkpoint blockade L Fang, D Ly, S Wang, JB Lee, H Kang, H Xu, J Yao, M Tsao, W Liu, ... Journal of Experimental & Clinical Cancer Research 38, 1-14, 2019 | 47 | 2019 |
Developing allogeneic double-negative T cells as a novel off-the-shelf adoptive cellular therapy for cancer JB Lee, H Kang, L Fang, C D'Souza, O Adeyi, L Zhang Clinical Cancer Research 25 (7), 2241-2253, 2019 | 45 | 2019 |
Mitochondrial and metabolic pathways regulate nuclear gene expression to control differentiation, stem cell function, and immune response in leukemia G Egan, DH Khan, JB Lee, S Mirali, L Zhang, AD Schimmer Cancer Discovery 11 (5), 1052-1066, 2021 | 36 | 2021 |
CRISPR screen identifies genes that sensitize AML cells to double-negative T-cell therapy F Soares, B Chen, JB Lee, M Ahmed, D Ly, E Tin, H Kang, Y Zeng, ... Blood, The Journal of the American Society of Hematology 137 (16), 2171-2181, 2021 | 31 | 2021 |
Infusion of ex-vivo expanded human TCR-αβ+ double-negative regulatory T cells delays onset of xenogeneic graft-versus-host disease P Achita, D Dervovic, D Ly, JB Lee, T Haug, B Joe, N Hirano, L Zhang Clinical & Experimental Immunology 193 (3), 386-399, 2018 | 30 | 2018 |
Allogeneic double-negative CAR-T cells inhibit tumor growth without off-tumor toxicities D Vasic, JB Lee, Y Leung, I Khatri, Y Na, D Abate-Daga, L Zhang Science Immunology 7 (70), eabl3642, 2022 | 26 | 2022 |
Cellular immunotherapy for acute myeloid leukemia: How specific should it be? JB Lee, B Chen, D Vasic, AD Law, L Zhang Blood reviews 35, 18-31, 2019 | 26 | 2019 |
Allogeneic Double‐Negative T cell therapy for Relapsed acute myeloid leukemia patients post allogeneic hematopoietic stem cell transplantation: A First‐In‐Human phase I study B Tang, JB Lee, S Cheng, T Pan, W Yao, D Wang, M Tu, Z Xiang, X Chu, ... American Journal of Hematology 97 (7), E264-E267, 2022 | 18* | 2022 |
State-of-art of cellular therapy for acute leukemia JB Lee, D Vasic, H Kang, KKL Fang, L Zhang International journal of molecular sciences 22 (9), 4590, 2021 | 18 | 2021 |
Enhancing therapeutic efficacy of double negative t cells against acute myeloid leukemia using idelalisib H Kang, JB Lee, I Khatri, Y Na, C D’Souza, A Arruda, MD Minden, ... Cancers 13 (20), 5039, 2021 | 6 | 2021 |
Adoptive cell therapy for T-cell malignancies KKL Fang, JB Lee, L Zhang Cancers 15 (1), 94, 2022 | 4 | 2022 |
Targeting T-cell malignancies using allogeneic double-negative CD4-CAR-T cells KKL Fang, J Lee, I Khatri, Y Na, L Zhang Journal for Immunotherapy of Cancer 11 (9), 2023 | 3 | 2023 |
Combination therapy with double negative T-cells L Zhang, JB Lee US Patent US10201572B2, 2019 | | 2019 |
Allogeneic Double Negative T cell Therapy as a Novel Treatment for AML Patients JB Lee University of Toronto (Canada), 2019 | | 2019 |
Combination of double negative T cells and Bcl-2 inhibitors for cancer therapy L Zhang, A Schimmer, JB Lee US Patent App. US 62/971,534, 0 | | |