Dysregulated GPCR signaling and therapeutic options in uveal melanoma V Chua, D Lapadula, C Randolph, JL Benovic, PB Wedegaertner, ... Molecular Cancer Research 15 (5), 501-506, 2017 | 83 | 2017 |
Co-targeting HGF/cMET signaling with MEK inhibitors in metastatic uveal melanoma H Cheng, V Chua, C Liao, TJ Purwin, M Terai, K Kageyama, MA Davies, ... Molecular cancer therapeutics 16 (3), 516-528, 2017 | 65 | 2017 |
Stromal fibroblast growth factor 2 reduces the efficacy of bromodomain inhibitors in uveal melanoma V Chua, M Orloff, JLF Teh, T Sugase, C Liao, TJ Purwin, BQ Lam, M Terai, ... EMBO Molecular Medicine 11 (2), e9081, 2019 | 62 | 2019 |
Inhibition of NF-κB–Dependent Signaling Enhances Sensitivity and Overcomes Resistance to BET Inhibition in Uveal Melanoma G Ambrosini, C Do, B Tycko, RB Realubit, C Karan, E Musi, RD Carvajal, ... Cancer research 79 (9), 2415-2425, 2019 | 36 | 2019 |
BAP1 mutant uveal melanoma is stratified by metabolic phenotypes with distinct vulnerability to metabolic inhibitors A Han, TJ Purwin, N Bechtel, C Liao, V Chua, E Seifert, T Sato, ZT Schug, ... Oncogene 40 (3), 618-632, 2021 | 33 | 2021 |
Novel therapeutic strategies and targets in advanced uveal melanoma V Chua, AE Aplin Current Opinion in Oncology 30 (2), 134-141, 2018 | 27 | 2018 |
Metabolic adaptations to MEK and CDK4/6 cotargeting in uveal melanoma JLF Teh, TJ Purwin, A Han, V Chua, P Patel, U Baqai, C Liao, N Bechtel, ... Molecular cancer therapeutics 19 (8), 1719-1726, 2020 | 26 | 2020 |
The latest on uveal melanoma research and clinical trials: updates from the cure ocular melanoma (CURE OM) science meeting (2019) V Chua, J Mattei, A Han, L Johnston, K LiPira, SM Selig, RD Carvajal, ... Clinical Cancer Research 27 (1), 28-33, 2021 | 24 | 2021 |
The AMP‐dependent kinase pathway is upregulated in BAP1 mutant uveal melanoma V Chua, A Han, N Bechtel, TJ Purwin, E Hunter, C Liao, JW Harbour, ... Pigment Cell & Melanoma Research 35 (1), 78-87, 2022 | 14 | 2022 |
Multi-omics profiling shows BAP1 loss is associated with upregulated cell adhesion molecules in uveal melanoma U Baqai, TJ Purwin, N Bechtel, V Chua, A Han, EJ Hartsough, ... Molecular cancer research 20 (8), 1260-1271, 2022 | 10 | 2022 |
Activity of ABCG2 Is Regulated by Its Expression and Localization in DHT and Cyclopamine‐Treated Breast Cancer Cells VYL Chua, I Larma, J Harvey, MA Thomas, JM Bentel Journal of Cellular Biochemistry 117 (10), 2249-2259, 2016 | 10 | 2016 |
Pyruvate dehydrogenase inactivation causes glycolytic phenotype in BAP1 mutant uveal melanoma A Han, V Chua, U Baqai, TJ Purwin, N Bechtel, E Hunter, M Tiago, ... Oncogene 41 (8), 1129-1139, 2022 | 9 | 2022 |
Kinome profiling identifies MARK3 and STK10 as potential therapeutic targets in uveal melanoma U Baqai, AM Kurimchak, IV Trachtenberg, TJ Purwin, JI Haj, A Han, K Luo, ... Journal of Biological Chemistry 299 (12), 2023 | 2 | 2023 |
Regulation of the ABCG2 drug efflux transporter in breast cancer cells VYL Chua, J Harvey, J Bentel Cancer Research 75 (15_Supplement), 715-715, 2015 | 2 | 2015 |
Abstract A009: NR2F1 inhibits Gaq/11-YAP-TAZ signaling and limits reactivation of uveal melanoma disseminated cancer cells via induction of dormancy R Kadamb, ML Anton, V Chua, T Purwin, MAN Toledano, A Aplin, ... Cancer Research 83 (2_Supplement_2), A009-A009, 2023 | 1 | 2023 |
Single cell resolution of intrapatient drug resistance mechanisms in metastatic melanoma HP Wilson, GL Mersky, JI Haj, J Teh, PF Cheng, S Caksa, CD Stefanski, ... Cancer Research 84 (6_Supplement), 6942-6942, 2024 | | 2024 |
Lineage commitment pathways epigenetically oppose oncogenic Gαq/11-YAP signaling in dormant disseminated uveal melanoma R Kadamb, ML Anton, TJ Purwin, V Chua, L Seeneevassen, J Teh, ... bioRxiv, 2024.03. 05.583565, 2024 | | 2024 |
Co-Targeting FASN and mTOR Suppresses Uveal Melanoma Growth A Han, D Mukha, V Chua, TJ Purwin, M Tiago, B Modasia, U Baqai, ... Cancers 15 (13), 3451, 2023 | | 2023 |
NR2F1 inhibits Gaq/11-YAP-TAZ signaling and limits reactivation of uveal melanoma disseminated cancer cells via induction of dormancy R Kadamb, ML Anton, V Chua, T Purwin, MAN Toledano, A Aplin, ... CANCER RESEARCH 83 (2), 2023 | | 2023 |
The aged tumor microenvironment influences tolerance to targeted therapy via NR2F1 overexpression in BRAF-mutant melanoma M Tiago, TJ Purwin, ME Fane, Y Chhabra, JLF Teh, R Kadamb, W Cai, ... CANCER RESEARCH 83 (2), 2023 | | 2023 |