A split prime editor with untethered reverse transcriptase and circular RNA template B Liu, X Dong, H Cheng, C Zheng, Z Chen, TC Rodríguez, SQ Liang, ... Nature Biotechnology 40 (9), 1388-1393, 2022 | 98 | 2022 |
CRISPR/Cas9: a powerful tool for identification of new targets for cancer treatment B Liu, A Saber, HJ Haisma Drug discovery today 24 (4), 955-970, 2019 | 77 | 2019 |
A flexible split prime editor using truncated reverse transcriptase improves dual-AAV delivery in mouse liver C Zheng, SQ Liang, B Liu, P Liu, SY Kwan, SA Wolfe, W Xue Molecular Therapy 30 (3), 1343-1351, 2022 | 65 | 2022 |
Inhibition of histone deacetylase 1 (HDAC1) and HDAC2 enhances CRISPR/Cas9 genome editing B Liu, S Chen, AL Rose, D Chen, F Cao, M Zwinderman, D Kiemel, ... Nucleic acids research 48 (2), 517-532, 2020 | 56 | 2020 |
Histone deacetylase inhibitors sensitize TRAIL-induced apoptosis in colon cancer cells B Zhang, B Liu, D Chen, R Setroikromo, HJ Haisma, WJ Quax Cancers 11 (5), 645, 2019 | 47 | 2019 |
CX Chemokine Receptor 7 Contributes to Survival of KRAS-Mutant Non-Small Cell Lung Cancer upon Loss of Epidermal Growth Factor Receptor B Liu, S Song, R Setroikromo, S Chen, W Hu, D Chen, AJ van der Wekken, ... Cancers 11 (4), 455, 2019 | 34 | 2019 |
D-dopachrome tautomerase contributes to lung epithelial repair via atypical chemokine receptor 3-dependent Akt signaling S Song, B Liu, H Habibie, J van den Bor, MJ Smit, R Gosens, X Wu, ... EBioMedicine 68, 2021 | 31 | 2021 |
A novel histone acetyltransferase inhibitor A485 improves sensitivity of non-small-cell lung carcinoma cells to TRAIL B Zhang, D Chen, B Liu, FJ Dekker, WJ Quax Biochemical pharmacology 175, 113914, 2020 | 28 | 2020 |
CRISPR/Cas9 for overcoming drug resistance in solid tumors A Saber, B Liu, P Ebrahimi, HJ Haisma DARU Journal of Pharmaceutical Sciences 28, 295-304, 2020 | 27 | 2020 |
CRISPR/Cas: a faster and more efficient gene editing system B Liu, H Xu, J Miao, A Zhang, X Kou, W Li, L Zhou, HG Xie, P Sirois, K Li Journal of nanoscience and nanotechnology 15 (3), 1946-1959, 2015 | 25 | 2015 |
CRISPR-mediated ablation of overexpressed EGFR in combination with sunitinib significantly suppresses renal cell carcinoma proliferation B Liu, OA Diaz Arguello, D Chen, S Chen, A Saber, HJ Haisma Plos one 15 (5), e0232985, 2020 | 21 | 2020 |
Transcriptional activation of cyclin D1 via HER2/HER3 contributes to EGFR-TKI resistance in lung cancer B Liu, D Chen, S Chen, A Saber, H Haisma Biochemical Pharmacology 178, 114095, 2020 | 17 | 2020 |
Modulating CRISPR/Cas9 genome-editing activity by small molecules S Chen, D Chen, B Liu, HJ Haisma Drug Discovery Today 27 (4), 951-966, 2022 | 14 | 2022 |
Template-jumping prime editing enables large insertion and exon rewriting in vivo C Zheng, B Liu, X Dong, N Gaston, EJ Sontheimer, W Xue Nature Communications 14 (1), 3369, 2023 | 13 | 2023 |
Targeted genome editing with a DNA-dependent DNA polymerase and exogenous DNA-containing templates B Liu, X Dong, C Zheng, D Keener, Z Chen, H Cheng, JK Watts, W Xue, ... Nature Biotechnology, 1-7, 2023 | 11 | 2023 |
A mutation-sensitive switch assay to detect five clinically significant epidermal growth factor receptor mutations B Liu, L Zhou, Q Wang, K Li Genetic Testing and Molecular Biomarkers 19 (6), 316-323, 2015 | 7 | 2015 |
Development of a flexible split prime editor using truncated reverse transcriptase C Zheng, SQ Liang, B Liu, P Liu, SY Kwan, SA Wolfe, W Xue BioRxiv, 2021.08. 26.457801, 2021 | 5 | 2021 |
Transcriptional activation of cyclin D1 via HER2/HER3 contributes to cell survival and EGFR tyrosine kinase inhibitor resistance in non-small cell lung carcinoma B Liu, D Chen, S Chen, A Saber, H Haisma bioRxiv, 851279, 2019 | 4 | 2019 |
Anouk La Rose, Deng Chen, Fangyuan Cao, Martijn Zwinderman, Dominik Kiemel, Manon Aıssi, Frank J Dekker, and Hidde J Haisma. Inhibition of histone deacetylase 1 (HDAC1) and … B Liu Nucleic Acids Research 48 (2), 517-532, 2019 | 2 | 2019 |
D-dopachrome tautomerase contributes to lung epithelial repair via atypical chemokine receptor 3-dependent Akt signaling H Habibie Elsevier, 2021 | 1 | 2021 |