Ferroptosis is controlled by the coordinated transcriptional regulation of glutathione and labile iron metabolism by the transcription factor BACH1 H Nishizawa, M Matsumoto, T Shindo, D Saigusa, H Kato, K Suzuki, ... Journal of Biological Chemistry 295 (1), 69-82, 2020 | 163 | 2020 |
BACH1 promotes pancreatic cancer metastasis by repressing epithelial genes and enhancing epithelial–mesenchymal transition M Sato, M Matsumoto, Y Saiki, M Alam, H Nishizawa, M Rokugo, ... Cancer Research 80 (6), 1279-1292, 2020 | 82 | 2020 |
Lipid peroxidation and the subsequent cell death transmitting from ferroptotic cells to neighboring cells H Nishizawa, M Matsumoto, G Chen, Y Ishii, K Tada, M Onodera, H Kato, ... Cell death & disease 12 (4), 332, 2021 | 58 | 2021 |
Ferroptosis: regulation by competition between NRF2 and BACH1 and propagation of the death signal H Nishizawa, M Yamanaka, K Igarashi The FEBS Journal 290 (7), 1688-1704, 2023 | 54 | 2023 |
The transcription factor BACH1 at the crossroads of cancer biology: from epithelial–mesenchymal transition to ferroptosis K Igarashi, H Nishizawa, Y Saiki, M Matsumoto Journal of Biological Chemistry 297 (3), 2021 | 53 | 2021 |
Pemetrexed and cisplatin for advanced non-squamous non-small cell lung cancer in Japanese patients: phase II study Y Kawano, F Ohyanagi, N Yanagitani, K Kudo, A Horiike, A Tanimoto, ... Anticancer research 33 (8), 3327-3333, 2013 | 39 | 2013 |
Infection perturbs Bach2-and Bach1-dependent erythroid lineage ‘choice’to cause anemia H Kato, A Itoh-Nakadai, M Matsumoto, Y Ishii, M Watanabe-Matsui, ... Nature immunology 19 (10), 1059-1070, 2018 | 32 | 2018 |
Phosphorylation of BACH1 switches its function from transcription factor to mitotic chromosome regulator and promotes its interaction with HMMR J Li, H Shima, H Nishizawa, M Ikeda, A Brydun, M Matsumoto, H Kato, ... Biochemical Journal 475 (5), 981-1002, 2018 | 25 | 2018 |
Phase II study of docetaxel-plus-bevacizumab combination therapy in patients previously treated for advanced non-squamous non-small cell lung cancer F Ohyanagi, N Yanagitani, K Kudo, Y Kawano, T Sakatani, A Tanimoto, ... Anticancer Research 34 (9), 5153-5158, 2014 | 16 | 2014 |
Bach1‐mediated suppression of p53 is inhibited by p19ARF independently of MDM2 H Nishizawa, K Ota, Y Dohi, T Ikura, K Igarashi Cancer Science 103 (5), 897-903, 2012 | 14 | 2012 |
Congenital sideroblastic anemia model due to ALAS2 mutation is susceptible to ferroptosis K Ono, T Fujiwara, K Saito, H Nishizawa, N Takahashi, C Suzuki, T Ochi, ... Scientific Reports 12 (1), 9024, 2022 | 7 | 2022 |
BACH1 Expression Is Promoted by Tank Binding Kinase 1 (TBK1) in Pancreatic Cancer Cells to Increase Iron and Reduce the Expression of E-Cadherin L Liu, M Matsumoto, M Matsui-Watanabe, K Ochiai, BKK Callens, ... Antioxidants 11 (8), 1460, 2022 | 6 | 2022 |
Ferroptosis model system by the re-expression of BACH1 R Irikura, H Nishizawa, K Nakajima, M Yamanaka, G Chen, K Tanaka, ... The Journal of Biochemistry 174 (3), 239-252, 2023 | 3 | 2023 |
Iron in Cancer Progression: Does BACH1 Promote Metastasis by Altering Iron Homeostasis? K Igarashi, H Nishizawa, M Matsumoto Metabolism and Epigenetic Regulation: Implications in Cancer, 67-80, 2022 | 1 | 2022 |
A phase II study of carboplatin and pemetrexed for elderly patients with advanced non-squamous non-small cell lung cancer H Nishizawa, A Horiike, R Saito, F Ohyanagi, K Kudo, N Yanagitani, ... Cancer Treatment and Research Communications 9, 100-105, 2016 | 1 | 2016 |
Phase II trial of bevacizumab, cisplatin, and pemetrexed in Japanese patients with advanced nonsquamous non-small cell lung cancer. N Yanagitani, F Ohyanagi, H Nishizawa, H Gyotoku, T Uenami, ... Journal of Clinical Oncology 32 (15_suppl), e19135-e19135, 2014 | 1 | 2014 |
TANK binding kinase 1 promotes BACH1 degradation through both phosphorylation-dependent and-independent mechanisms without relying on heme and FBXO22 L Liu, M Matsumoto, M Watanabe-Matsui, T Nakagawa, Y Nagasawa, ... International Journal of Molecular Sciences 25 (8), 4141, 2024 | | 2024 |
Cysteine restriction induces ferroptosis depending on the polyamine biosynthetic pathway in hepatic cancer cells K Tada, H Nishizawa, H Shima, A Muto, M Wada, K Igarashi bioRxiv, 2024.02. 29.582667, 2024 | | 2024 |
Altered Transcription By GATA1 Impairs Autophagy and Prevents Ferroptosis in X-Linked Sideroblastic Anemia K Ono, T Fujiwara, H Shima, H Nishizawa, C Suzuki, N Takahashi, H Kato, ... Blood 140 (Supplement 1), 2467-2468, 2022 | | 2022 |
NEW MARKER OF THE EPITHELIAL-MESENCHYMAL TRANSITION IN PANCREA CANCER K Igarashi, M Matsumoto, M Sato, H NISHIZAWA | | 2022 |