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Hironari Nishizawa
Hironari Nishizawa
Department of Biochemistry, Tohoku University Graduate School of Medicine
Verified email at med.tohoku.ac.jp
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Cited by
Year
Ferroptosis is controlled by the coordinated transcriptional regulation of glutathione and labile iron metabolism by the transcription factor BACH1
H Nishizawa, M Matsumoto, T Shindo, D Saigusa, H Kato, K Suzuki, ...
Journal of Biological Chemistry 295 (1), 69-82, 2020
1632020
BACH1 promotes pancreatic cancer metastasis by repressing epithelial genes and enhancing epithelial–mesenchymal transition
M Sato, M Matsumoto, Y Saiki, M Alam, H Nishizawa, M Rokugo, ...
Cancer Research 80 (6), 1279-1292, 2020
822020
Lipid peroxidation and the subsequent cell death transmitting from ferroptotic cells to neighboring cells
H Nishizawa, M Matsumoto, G Chen, Y Ishii, K Tada, M Onodera, H Kato, ...
Cell death & disease 12 (4), 332, 2021
582021
Ferroptosis: regulation by competition between NRF2 and BACH1 and propagation of the death signal
H Nishizawa, M Yamanaka, K Igarashi
The FEBS Journal 290 (7), 1688-1704, 2023
542023
The transcription factor BACH1 at the crossroads of cancer biology: from epithelial–mesenchymal transition to ferroptosis
K Igarashi, H Nishizawa, Y Saiki, M Matsumoto
Journal of Biological Chemistry 297 (3), 2021
532021
Pemetrexed and cisplatin for advanced non-squamous non-small cell lung cancer in Japanese patients: phase II study
Y Kawano, F Ohyanagi, N Yanagitani, K Kudo, A Horiike, A Tanimoto, ...
Anticancer research 33 (8), 3327-3333, 2013
392013
Infection perturbs Bach2-and Bach1-dependent erythroid lineage ‘choice’to cause anemia
H Kato, A Itoh-Nakadai, M Matsumoto, Y Ishii, M Watanabe-Matsui, ...
Nature immunology 19 (10), 1059-1070, 2018
322018
Phosphorylation of BACH1 switches its function from transcription factor to mitotic chromosome regulator and promotes its interaction with HMMR
J Li, H Shima, H Nishizawa, M Ikeda, A Brydun, M Matsumoto, H Kato, ...
Biochemical Journal 475 (5), 981-1002, 2018
252018
Phase II study of docetaxel-plus-bevacizumab combination therapy in patients previously treated for advanced non-squamous non-small cell lung cancer
F Ohyanagi, N Yanagitani, K Kudo, Y Kawano, T Sakatani, A Tanimoto, ...
Anticancer Research 34 (9), 5153-5158, 2014
162014
Bach1‐mediated suppression of p53 is inhibited by p19ARF independently of MDM2
H Nishizawa, K Ota, Y Dohi, T Ikura, K Igarashi
Cancer Science 103 (5), 897-903, 2012
142012
Congenital sideroblastic anemia model due to ALAS2 mutation is susceptible to ferroptosis
K Ono, T Fujiwara, K Saito, H Nishizawa, N Takahashi, C Suzuki, T Ochi, ...
Scientific Reports 12 (1), 9024, 2022
72022
BACH1 Expression Is Promoted by Tank Binding Kinase 1 (TBK1) in Pancreatic Cancer Cells to Increase Iron and Reduce the Expression of E-Cadherin
L Liu, M Matsumoto, M Matsui-Watanabe, K Ochiai, BKK Callens, ...
Antioxidants 11 (8), 1460, 2022
62022
Ferroptosis model system by the re-expression of BACH1
R Irikura, H Nishizawa, K Nakajima, M Yamanaka, G Chen, K Tanaka, ...
The Journal of Biochemistry 174 (3), 239-252, 2023
32023
Iron in Cancer Progression: Does BACH1 Promote Metastasis by Altering Iron Homeostasis?
K Igarashi, H Nishizawa, M Matsumoto
Metabolism and Epigenetic Regulation: Implications in Cancer, 67-80, 2022
12022
A phase II study of carboplatin and pemetrexed for elderly patients with advanced non-squamous non-small cell lung cancer
H Nishizawa, A Horiike, R Saito, F Ohyanagi, K Kudo, N Yanagitani, ...
Cancer Treatment and Research Communications 9, 100-105, 2016
12016
Phase II trial of bevacizumab, cisplatin, and pemetrexed in Japanese patients with advanced nonsquamous non-small cell lung cancer.
N Yanagitani, F Ohyanagi, H Nishizawa, H Gyotoku, T Uenami, ...
Journal of Clinical Oncology 32 (15_suppl), e19135-e19135, 2014
12014
TANK binding kinase 1 promotes BACH1 degradation through both phosphorylation-dependent and-independent mechanisms without relying on heme and FBXO22
L Liu, M Matsumoto, M Watanabe-Matsui, T Nakagawa, Y Nagasawa, ...
International Journal of Molecular Sciences 25 (8), 4141, 2024
2024
Cysteine restriction induces ferroptosis depending on the polyamine biosynthetic pathway in hepatic cancer cells
K Tada, H Nishizawa, H Shima, A Muto, M Wada, K Igarashi
bioRxiv, 2024.02. 29.582667, 2024
2024
Altered Transcription By GATA1 Impairs Autophagy and Prevents Ferroptosis in X-Linked Sideroblastic Anemia
K Ono, T Fujiwara, H Shima, H Nishizawa, C Suzuki, N Takahashi, H Kato, ...
Blood 140 (Supplement 1), 2467-2468, 2022
2022
NEW MARKER OF THE EPITHELIAL-MESENCHYMAL TRANSITION IN PANCREA CANCER
K Igarashi, M Matsumoto, M Sato, H NISHIZAWA
2022
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