Developmental origin, functional maintenance and genetic rescue of osteoclasts CE Jacome-Galarza, GI Percin, JT Muller, E Mass, T Lazarov, J Eitler, ... Nature 568 (7753), 541-545, 2019 | 391 | 2019 |
“UniCAR”-modified off-the-shelf NK-92 cells for targeting of GD2-expressing tumour cells N Mitwasi, A Feldmann, C Arndt, S Koristka, N Berndt, J Jureczek, ... Scientific reports 10 (1), 2141, 2020 | 82 | 2020 |
1, 2-propanediol-trehalose mixture as a potent quantitative real-time PCR enhancer H Horáková, I Polakovičová, GM Shaik, J Eitler, V Bugajev, L Dráberová, ... Bmc Biotechnology 11, 1-16, 2011 | 54 | 2011 |
Inability of granule polarization by NK cells defines tumor resistance and can be overcome by CAR or ADCC mediated targeting J Eitler, N Wotschel, N Miller, L Boissel, HG Klingemann, W Wels, T Tonn Journal for immunotherapy of cancer 9 (1), 2021 | 23 | 2021 |
CSF1R regulates the dendritic cell pool size in adult mice via embryo-derived tissue-resident macrophages GI Percin, J Eitler, A Kranz, J Fu, JW Pollard, R Naumann, C Waskow Nature communications 9 (1), 5279, 2018 | 22 | 2018 |
Engineering NK-CAR.19 cells with the IL-15/IL-15Rα complex improved proliferation and anti-tumor effect in vivo RN Silvestre, J Eitler, JTC de Azevedo, MC Tirapelle, DMC Fantacini, ... Frontiers in Immunology 14, 1226518, 2023 | 9 | 2023 |
Preclinical assessment of CAR-NK cell-mediated killing efficacy and pharmacokinetics in a rapid zebrafish xenograft model of metastatic breast cancer N Murali Shankar, P Ortiz-Montero, A Kurzyukova, W Rackwitz, SR Künzel, ... Frontiers in Immunology 14, 1254821, 2023 | 3 | 2023 |
CAR-mediated targeting of NK cells overcomes tumor immune escape caused by ICAM-1 downregulation J Eitler, W Rackwitz, N Wotschel, V Gudipati, NM Shankar, A Sidorenkova, ... Journal for Immunotherapy of Cancer 12 (2), 2024 | 2 | 2024 |
216 Dual targeting of CAR-NK cells to PD-L1 and ErbB2 facilitates specific elimination of cancer cells of solid tumor origin and overcomes immune escape by antigen loss J Eitler, K Freudenberg, PO Montero, W Rackwitz, W Wels, T Tonn Journal for ImmunoTherapy of Cancer 10 (Suppl 2), 2022 | 2 | 2022 |
Immunotherapy: Late breaking abstract: CD19-CAR NK cells co-expressing IL15/IL15Rα show enhanced cytotoxicity against B-cell leukemia RN Silvestre, J Eitler, JTTC de Azevedo, T Tonn, V Picanço-Castro Cytotherapy 24 (5), S39-S40, 2022 | 1 | 2022 |
Live cell imaging of lytic granule motility in anti-erbb2 car nk cells and fcr nk cells plus herceptin towards erbb2+ breast cancer cells J Eitler, N Wotschel, H Klingemann, WS Wels, T Tonn Cytotherapy 22 (5), S199, 2020 | 1 | 2020 |
FAPα-TARGETED IMMUNOTHERAPY WITH SIBROTUZUMAB AND HIGH AFFINITY FC-RECEPTOR EXPRESSING NK92 CELLS: A PROMISING APPROACH TO REVERSE FIBROSIS SR Kuenzel, M Arriens, W Rackwitz, J Pappermann, J Thiel, ... Cytotherapy 26 (6), S177, 2024 | | 2024 |
Application of chimeric antigen receptor-natural killer cells for the treatment of type 1 diabetes C Steenblock, J Eitler, IT Oikonomakos, M Arriens, SR Künzel, T Tonn, ... Exploration of Endocrine and Metabolic Diseases 1 (1), 4-11, 2024 | | 2024 |
DUAL TARGETING OF PD-L1 AND ERBB2 BY CAR-NK CELLS ENABLES SPECIFIC ELIMINATION OF SOLID TUMOR CELLS AND OVERCOMES IMMUNE ESCAPE VIA ANTIGEN LOSS J Eitler, K Freudenberg, I Ben-Horin, P Montero, W Rackwitz, W Wels, ... HUMAN GENE THERAPY 34 (21-22), A15-A16, 2023 | | 2023 |
442-Q CAR-mediated targeting of NK cells overcomes tumor immune escape caused by ICAM-1 downregulation J Eitler, W Rackwitz, N Wotschel, V Gudipati, J Huppa, PO Montero, ... Journal for ImmunoTherapy of Cancer 11 (Suppl 2), 2023 | | 2023 |
Preclinical assessment of CAR-NK cell-mediated killing efficacy and pharmacokinetics in a rapid zebrafish xenograft model of metastatic breast cancer A Kurzyukova, W Rackwitz, S Künzel, WS Wels, T Tonn, F Knopf, J Eitler | | 2023 |
Immunotherapy: DUAL TARGETING OF CAR-NK CELLS TO PD-L1 AND HER2 FACILITATES SPECIFIC ELIMINATION OF CANCER CELLS OF SOLID TUMOR ORIGIN AND OVERCOMES IMMUNE ESCAPE BY ANTIGEN LOSS J Eitler, K Freudenberg, PO Montero, W Rackwitz, WS Wels, T Tonn Cytotherapy 25 (6), S221-S222, 2023 | | 2023 |
Live-cell imaging for analysis of the NK cell immunological synapse N Wotschel, PO Montero, WS Wels, T Tonn, J Eitler Methods in Cell Biology 178, 1-12, 2023 | | 2023 |
KTeXpand–a novel microfluidic device for advanced cell based cross matching D Schneider, S Behrens, J Philipp, J Eitler, J Stumpf, T Tonn, F Sonntag, ... Current Directions in Biomedical Engineering 8 (2), 501-504, 2022 | | 2022 |
PARP inhibitors render ovarian and breast carcinoma cells otherwise resistant to NK cell-mediated lysis sensitive J Eitler, T Gutbrod, A Sidorenkova, MP Ortiz, M Bornhauser, WS Wels, ... ONCOLOGY RESEARCH AND TREATMENT 45 (SUPPL 2), 212-212, 2022 | | 2022 |