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Jerzy Michal Dziekan
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Declining Efficacy of Artemisinin Combination Therapy Against P. Falciparum Malaria on the Thai–Myanmar Border (2003–2013): The Role of Parasite Genetic …
AP Phyo, EA Ashley, TJC Anderson, Z Bozdech, VI Carrara, K Sriprawat, ...
Clinical infectious diseases 63 (6), 784-791, 2016
2302016
Identifying purine nucleoside phosphorylase as the target of quinine using cellular thermal shift assay
JM Dziekan, H Yu, D Chen, L Dai, G Wirjanata, A Larsson, N Prabhu, ...
Science translational medicine 11 (473), eaau3174, 2019
1802019
Cellular thermal shift assay for the identification of drug–target interactions in the Plasmodium falciparum proteome
JM Dziekan, G Wirjanata, L Dai, KD Go, H Yu, YT Lim, L Chen, LC Wang, ...
Nature Protocols 15 (6), 1881-1921, 2020
812020
Human peroxiredoxin 6 is essential for malaria parasites and provides a host-based drug target
MP Wagner, P Formaglio, O Gorgette, JM Dziekan, C Huon, I Berneburg, ...
Cell Reports 39 (11), 110923, 2022
102022
Genomic, transcriptomic, and metabolomic analysis of Oldenlandia corymbosa reveals the biosynthesis and mode of action of anti‐cancer metabolites
I Julca, D Mutwil‐Anderwald, V Manoj, Z Khan, SK Lai, LK Yang, IT Beh, ...
Journal of Integrative Plant Biology 65 (6), 1442-1466, 2023
92023
Identification of an inhibitory pocket in falcilysin provides a new avenue for malaria drug development
G Wirjanata, J Lin, JM Dziekan, A El Sahili, Z Chung, S Tjia, NEB Zulkifli, ...
bioRxiv, 2021.04. 08.438947, 2021
32021
Short tandem repeat polymorphism in the promoter region of cyclophilin 19B drives its transcriptional upregulation and contributes to drug resistance in the malaria parasite …
M Kucharski, G Wirjanata, S Nayak, J Boentoro, JM Dziekan, C Assisi, ...
PLoS pathogens 19 (1), e1011118, 2023
22023
Aryl amino acetamides prevent the development of Plasmodium falciparum rings via inhibition of the lipid transfer protein PfSTART1
MG Dans, C Boulet, GM Watson, W Nguyen, JM Dziekan, C Evelyn, ...
bioRxiv, 2023.11. 02.565411, 2023
12023
Identification and structural validation of purine nucleoside phosphorylase from Plasmodium falciparum as a target of MMV000848
Z Chung, J Lin, G Wirjanata, JM Dziekan, A El Sahili, PR Preiser, ...
Journal of Biological Chemistry 300 (1), 2024
2024
Genetic validation of PfFKBP35 as an antimalarial drug target
BT Thommen, JM Dziekan, F Achcar, S Tjia, A Passecker, K Buczak, C Gumpp, A ...
eLife, https://doi.org/10.7554/eLife.86975.4, 2023
2023
Plasmodium falciparum Eukaryotic Translation Initiation Factor 3 is Stabilized by Quinazoline-Quinoline Bisubstrate Inhibitors
I Dobrescu, E Hammam, JM Dziekan, A Claës, L Halby, P Preiser, ...
ACS Infectious Diseases 9 (6), 1257-1266, 2023
2023
Peroxiredoxin 6
MP Wagner, P Formaglio, O Gorgette, JM Dziekan, C Huon, I Berneburg, ...
Cell reports 39 (11), 110923-110923, 2022
2022
Molecular analysis of antimalarial therapies: from drug development to mode of action
JM Dziekan
Nanyang Technological University, 2019
2019
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Articles 1–13