Cinnamic acid activates PPARα to stimulate Lysosomal biogenesis and lower Amyloid plaque pathology in an Alzheimer's disease mouse model S Chandra, A Roy, M Jana, K Pahan Neurobiology of disease 124, 379-395, 2019 | 113 | 2019 |
Selective disruption of TLR2-MyD88 interaction inhibits inflammation and attenuates Alzheimer’s pathology SB Rangasamy, M Jana, A Roy, GT Corbett, M Kundu, S Chandra, ... The Journal of clinical investigation 128 (10), 4297-4312, 2018 | 112 | 2018 |
Aspirin induces lysosomal biogenesis and attenuates amyloid plaque pathology in a mouse model of Alzheimer's disease via PPARα S Chandra, M Jana, K Pahan Journal of Neuroscience 38 (30), 6682-6699, 2018 | 112 | 2018 |
Multi-omics analysis of microglial extracellular vesicles from human Alzheimer's Disease brain reveals disease-associated signatures SW Cohn, M Melnik, C Huang, B Teter, S Chandra, LB Mcintire, V John, ... Frontiers in Pharmacology, 3078, 0 | 60 | |
Gemfibrozil, a lipid-lowering drug, lowers amyloid plaque pathology and enhances memory in a mouse model of Alzheimer’s disease via peroxisome proliferator-activated receptor α S Chandra, K Pahan Journal of Alzheimer's disease reports 3 (1), 149-168, 2019 | 48 | 2019 |
Dual neutral sphingomyelinase-2/acetylcholinesterase inhibitors for the treatment of Alzheimer’s disease T Bilousova, BJ Simmons, RR Knapp, CJ Elias, J Campagna, M Melnik, ... ACS chemical biology 15 (6), 1671-1684, 2020 | 23 | 2020 |
Pharmacological inhibition of nSMase2 reduces brain exosome release and α-synuclein pathology in a Parkinson’s disease model C Zhu, T Bilousova, S Focht, M Jun, CJ Elias, M Melnik, S Chandra, ... Molecular brain 14, 1-8, 2021 | 18 | 2021 |
PPAR α Between Aspirin and Plaque Clearance S Chandra, A Roy, DR Patel, K Pahan Journal of Alzheimer's Disease 71 (2), 389-397, 2019 | 17 | 2019 |
Treadmill exercise reduces α-synuclein spreading via PPARα D Dutta, RK Paidi, S Raha, A Roy, S Chandra, K Pahan Cell reports 40 (2), 111058, 2022 | 16 | 2022 |
Upregulation of tripeptidyl-peptidase 1 by 3-hydroxy-(2, 2)-dimethyl butyrate, a brain endogenous ligand of PPARα: Implications for late-infantile Batten disease therapy S Chakrabarti, S Chandra, A Roy, S Dasarathi, M Kundu, K Pahan Neurobiology of disease 127, 362-373, 2019 | 5 | 2019 |
A mitochondrial inside-out iron-calcium signal reveals drug targets for Parkinson’s disease V Bharat, AS Durairaj, R Vanhauwaert, L Li, CM Muir, S Chandra, ... Cell reports 42 (12), 2023 | 4 | 2023 |
Correction to: Pharmacological inhibition of nSMase2 reduces brain exosome release and α-synuclein pathology in a Parkinson’s disease model C Zhu, T Bilousova, S Focht, M Jun, CJ Elias, M Melnik, S Chandra, ... Molecular Brain 14 (1), 1-1, 2021 | 3 | 2021 |
O5‐05‐02: GEMFIBROZIL, A LIPID‐LOWERING DRUG, ATTENUATES AMYLOID PLAQUE PATHOLOGY AND ENHANCES MEMORY VIA PPARα S Chandra, K Pahan Alzheimer's & Dementia 14 (7S_Part_31), P1655-P1656, 2018 | 1 | 2018 |
Cinnamic acid stimulates lysosomal biogenesis and enhances memory in an animal model of Alzheimer's Disease via PPAR alpha S Chandra, M Jana, K Pahan JOURNAL OF NEUROIMMUNE PHARMACOLOGY 13, S13-S13, 2018 | 1 | 2018 |
Mitochondrial calcium transport during autophagy initiation S Chandra, P Katiyar, AS Durairaj, X Wang Mitochondrial Communications, 2024 | | 2024 |
Dual Neutral Sphingomyelinase2/Acetylcholinesterase Inhibitors as a novel approach in Alzheimer’s disease therapeutics development T Bilousova, B Simmons, RR Knapp, CJ Elias, JJ Campagna, M Melnik, ... 2021 Alzheimer's Association International Conference, 2021 | | 2021 |