| Drug discovery targeting bromodomain-containing protein 4 Z Liu, P Wang, H Chen, EA Wold, B Tian, AR Brasier, J Zhou Journal of medicinal chemistry 60 (11), 4533-4558, 2017 | 269 | 2017 |
| An update on poly (ADP-ribose) polymerase-1 (PARP-1) inhibitors: opportunities and challenges in cancer therapy YQ Wang, PY Wang, YT Wang, GF Yang, A Zhang, ZH Miao Journal of medicinal chemistry 59 (21), 9575-9598, 2016 | 193 | 2016 |
| Discovery of potent and selective BRD4 inhibitors capable of blocking TLR3-induced acute airway inflammation Z Liu, B Tian, H Chen, P Wang, AR Brasier, J Zhou European journal of medicinal chemistry 151, 450-461, 2018 | 63 | 2018 |
| Discovery of orally bioavailable chromone derivatives as potent and selective BRD4 inhibitors: scaffold hopping, optimization, and pharmacological evaluation Z Liu, H Chen, P Wang, Y Li, EA Wold, PG Leonard, S Joseph, AR Brasier, ... Journal of medicinal chemistry 63 (10), 5242-5256, 2020 | 61 | 2020 |
| Proteolysis targeting chimera (PROTAC): a paradigm-shifting approach in small molecule drug discovery P Wang, J Zhou Current topics in medicinal chemistry 18 (16), 1354-1356, 2018 | 56 | 2018 |
| Exchange proteins directly activated by cAMP (EPACs): Emerging therapeutic targets P Wang, Z Liu, H Chen, N Ye, X Cheng, J Zhou Bioorganic & medicinal chemistry letters 27 (8), 1633-1639, 2017 | 53 | 2017 |
| Methylglyoxal and a spinal TRPA1-AC1-Epac cascade facilitate pain in the db/db mouse model of type 2 diabetes RB Griggs, DF Santos, DE Laird, S Doolen, RR Donahue, CR Wessel, ... Neurobiology of disease 127, 76-86, 2019 | 36 | 2019 |
| Regio-and stereospecific synthesis of oridonin D-ring aziridinated analogues for the treatment of triple-negative breast cancer via mediated irreversible covalent warheads Y Ding, D Li, C Ding, P Wang, Z Liu, EA Wold, N Ye, H Chen, MA White, ... Journal of medicinal chemistry 61 (7), 2737-2752, 2018 | 32 | 2018 |
| Small-molecule inhibitors targeting the canonical WNT signaling pathway for the treatment of cancer Z Liu, P Wang, EA Wold, Q Song, C Zhao, C Wang, J Zhou Journal of medicinal chemistry 64 (8), 4257-4288, 2021 | 28 | 2021 |
| Discovery, X-ray crystallography, and anti-inflammatory activity of bromodomain-containing protein 4 (BRD4) BD1 inhibitors targeting a distinct new binding site Z Liu, Y Li, H Chen, HT Lai, P Wang, SY Wu, EA Wold, PG Leonard, ... Journal of medicinal chemistry 65 (3), 2388-2408, 2022 | 26 | 2022 |
| InBr3-Mediated One-Pot Synthesis of 2-(Polyhydroxylatedalkyl)-N-aryl-/-alkylpyrroles from 1,2-Cyclopropa-3-pyranone and Amines P Wang, S Song, Z Miao, G Yang, A Zhang Organic letters 15 (15), 3852-3855, 2013 | 26 | 2013 |
| Synthesis and pharmacological evaluation of noncatechol G protein biased and unbiased dopamine D1 receptor agonists P Wang, DE Felsing, H Chen, SR Raval, JA Allen, J Zhou ACS Medicinal Chemistry Letters 10 (5), 792-799, 2019 | 21 | 2019 |
| Exchange proteins directly activated by cAMP and their roles in respiratory syncytial virus infection EJ Choi, Y Ren, Y Chen, S Liu, W Wu, J Ren, P Wang, RP Garofalo, ... Journal of virology 92 (22), 10.1128/jvi. 01200-18, 2018 | 21 | 2018 |
| Discovery of potent and brain-penetrant GPR52 agonist that suppresses psychostimulant behavior P Wang, DE Felsing, H Chen, SJ Stutz, RE Murphy, KA Cunningham, ... Journal of medicinal chemistry 63 (22), 13951-13972, 2020 | 17 | 2020 |
| Mechanism of action of an EPAC1-selective competitive partial agonist H Shao, H Mohamed, S Boulton, J Huang, P Wang, H Chen, J Zhou, ... Journal of medicinal chemistry 63 (9), 4762-4775, 2020 | 16 | 2020 |
| Palladium-catalyzed N-arylation of 2-aminobenzothiazole-4-carboxylates/carboxamides: facile synthesis of PARP14 inhibitors P Wang, J Li, X Jiang, Z Liu, N Ye, Y Xu, G Yang, Y Xu, A Zhang Tetrahedron 70 (35), 5666-5673, 2014 | 16 | 2014 |
| Small‐Molecule Neuromedin U Receptor 2 Agonists Suppress Food Intake and Decrease Visceral Fat in Animal Models CM Sampson, JM Kasper, DE Felsing, SR Raval, N Ye, P Wang, ... Pharmacology Research & Perspectives 6 (5), e00425, 2018 | 15 | 2018 |
| Synthesis and biochemical evaluation of noncyclic nucleotide exchange proteins directly activated by cAMP 1 (EPAC1) regulators P Wang, U Luchowska-Stanska, B Van Basten, H Chen, Z Liu, J Wiejak, ... Journal of medicinal chemistry 63 (10), 5159-5184, 2020 | 13 | 2020 |
| Identification of peptidomimetics as novel chemical probes modulating fibroblast growth factor 14 (FGF14) and voltage-gated sodium channel 1.6 (Nav1. 6) protein-protein … Z Liu, P Wadsworth, AK Singh, H Chen, P Wang, O Folorunso, P Scaduto, ... Bioorganic & medicinal chemistry letters 29 (3), 413-419, 2019 | 12 | 2019 |
| Structure-activity relationships of 2-substituted phenyl-N-phenyl-2-oxoacetohydrazonoyl cyanides as novel antagonists of exchange proteins directly activated by cAMP (EPACs) Z Liu, Y Zhu, H Chen, P Wang, FC Mei, N Ye, X Cheng, J Zhou Bioorganic & medicinal chemistry letters 27 (23), 5163-5166, 2017 | 12 | 2017 |
