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Kurtis Mengham
Kurtis Mengham
Verified email at sussex.ac.uk
Title
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Cited by
Year
Metal-and UV-catalyzed oxidation results in trapped amyloid-β intermediates revealing that self-assembly is required for Aβ-induced cytotoxicity
MB Maina, G Burra, YK Al-Hilaly, K Mengham, K Fennell, LC Serpell
Iscience 23 (10), 2020
182020
Dityrosine Cross-links are Present in Alzheimer’s Disease-derived Tau Oligomers and Paired Helical Filaments (PHF) which Promotes the Stability of the PHF-core Tau (297–391) In …
MB Maina, YK Al-Hilaly, S Oakley, G Burra, T Khanom, L Biasetti, ...
Journal of Molecular Biology 434 (19), 167785, 2022
112022
An additive-free model for Tau self-assembly
YK Al-Hilaly, KE Marshall, L Lutter, L Biasetti, K Mengham, CR Harrington, ...
Protein Aggregation: Methods and Protocols, 163-188, 2022
22022
Dityrosine cross-link trapping of amyloid-β intermediates reveals that self-assembly is required for Aβ-induced cytotoxicity
MB Maina, K Mengham, GK Burra, YA Al-Hilaly, LC Serpell
bioRxiv, 2020.03. 25.007690, 2020
22020
Shapeshifting tau: from intrinsically disordered to paired-helical filaments
K Mengham, Y Al-Hilaly, S Oakley, K Kasbi, MB Maina, LC Serpell
Essays in Biochemistry 66 (7), 1001-1011, 2022
12022
Correlative cryo-soft X-ray tomography and cryo-structured illumination microscopy reveal changes to lysosomes in amyloid-β-treated neurons
KE Marshall, K Mengham, MC Spink, L Vania, HJ Pollard, MC Darrow, ...
Structure 32 (5), 585-593. e3, 2024
2024
Investigating early-stage protein misfolding of Abeta and tau in neurodegenerative diseases
K Mengham
University of Sussex, 2023
2023
Correlative cryo-soft X-ray tomography reveals defective lysosomes in amyloid-β oligomer treated hippocampal neurons
KE Marshall, K Mengham, MC Spink, L Vania, HJ Pollard, MC Darrow, ...
2022
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