Metal-and UV-catalyzed oxidation results in trapped amyloid-β intermediates revealing that self-assembly is required for Aβ-induced cytotoxicity MB Maina, G Burra, YK Al-Hilaly, K Mengham, K Fennell, LC Serpell Iscience 23 (10), 2020 | 18 | 2020 |
Dityrosine Cross-links are Present in Alzheimer’s Disease-derived Tau Oligomers and Paired Helical Filaments (PHF) which Promotes the Stability of the PHF-core Tau (297–391) In … MB Maina, YK Al-Hilaly, S Oakley, G Burra, T Khanom, L Biasetti, ... Journal of Molecular Biology 434 (19), 167785, 2022 | 11 | 2022 |
An additive-free model for Tau self-assembly YK Al-Hilaly, KE Marshall, L Lutter, L Biasetti, K Mengham, CR Harrington, ... Protein Aggregation: Methods and Protocols, 163-188, 2022 | 2 | 2022 |
Dityrosine cross-link trapping of amyloid-β intermediates reveals that self-assembly is required for Aβ-induced cytotoxicity MB Maina, K Mengham, GK Burra, YA Al-Hilaly, LC Serpell bioRxiv, 2020.03. 25.007690, 2020 | 2 | 2020 |
Shapeshifting tau: from intrinsically disordered to paired-helical filaments K Mengham, Y Al-Hilaly, S Oakley, K Kasbi, MB Maina, LC Serpell Essays in Biochemistry 66 (7), 1001-1011, 2022 | 1 | 2022 |
Correlative cryo-soft X-ray tomography and cryo-structured illumination microscopy reveal changes to lysosomes in amyloid-β-treated neurons KE Marshall, K Mengham, MC Spink, L Vania, HJ Pollard, MC Darrow, ... Structure 32 (5), 585-593. e3, 2024 | | 2024 |
Investigating early-stage protein misfolding of Abeta and tau in neurodegenerative diseases K Mengham University of Sussex, 2023 | | 2023 |
Correlative cryo-soft X-ray tomography reveals defective lysosomes in amyloid-β oligomer treated hippocampal neurons KE Marshall, K Mengham, MC Spink, L Vania, HJ Pollard, MC Darrow, ... | | 2022 |