Opposing functions of interferon coordinate adaptive and innate immune responses to cancer immune checkpoint blockade JL Benci, LR Johnson, R Choa, Y Xu, J Qiu, Z Zhou, B Xu, D Ye, ... Cell 178 (4), 933-948. e14, 2019 | 355 | 2019 |
The immunostimulatory RNA RN7SL1 enables CAR-T cells to enhance autonomous and endogenous immune function LR Johnson, DY Lee, JS Eacret, D Ye, CH June, AJ Minn Cell 184 (19), 4981-4995. e14, 2021 | 109 | 2021 |
Gene expression–based discovery of atovaquone as a STAT3 inhibitor and anticancer agent M Xiang, H Kim, VT Ho, SR Walker, M Bar-Natan, M Anahtar, S Liu, ... Blood, The Journal of the American Society of Hematology 128 (14), 1845-1853, 2016 | 95 | 2016 |
Cancer cells resistant to immune checkpoint blockade acquire interferon-associated epigenetic memory to sustain T cell dysfunction J Qiu, B Xu, D Ye, D Ren, S Wang, JL Benci, Y Xu, H Ishwaran, JC Beltra, ... Nature cancer 4 (1), 43-61, 2023 | 39 | 2023 |
The kinases IKBKE and TBK1 regulate MYC-dependent survival pathways through YB-1 in AML and are targets for therapy S Liu, AE Marneth, G Alexe, SR Walker, HI Gandler, DQ Ye, K Labella, ... Blood advances 2 (23), 3428-3442, 2018 | 33 | 2018 |
Mutant KRAS downregulates the receptor for leukemia inhibitory factor (LIF) to enhance a signature of glycolysis in pancreatic cancer and lung cancer S Liu, HI Gandler, I Tošić, DQ Ye, ZT Giaccone, DA Frank Molecular Cancer Research 19 (8), 1283-1295, 2021 | 18 | 2021 |
Clinical and molecular features of acquired resistance to immunotherapy in non-small cell lung cancer D Memon, AJ Schoenfeld, D Ye, G Fromm, H Rizvi, X Zhang, MR Keddar, ... Cancer Cell, 2024 | 8 | 2024 |
Durable response and improved CD8 T cell plasticity in lung cancer patients after PD1 blockade and JAK inhibition D Mathew, ME Marmarelis, C Foley, JM Bauml, D Ye, R Ghinnagow, ... medRxiv, 2022.11. 05.22281973, 2022 | 5 | 2022 |
RUNX1 is required in granulocyte–monocyte progenitors to attenuate inflammatory cytokine production by neutrophils AU Zezulin, D Yen, D Ye, ED Howell, E Bresciani, J Diemer, J Ren, ... Genes & Development 37 (13-14), 605-620, 2023 | 3 | 2023 |
Enhanced immunotherapy of cancer using targeted transcriptional modulators D Frank, YE Darwin | 1 | 2019 |
Persistent Cancer Cells Alter Interferon Signaling After Immune Checkpoint Blockade D Ye University of Pennsylvania, 2023 | | 2023 |
P1. 15-07 Phase II Study of Pembrolizumab and Itacitinib for First Line Treatment of Metastatic NSCLC Expressing PD-L1 ME Marmarelis, D Mathew, JM Bauml, WT Hwang, J Zhang, A Singh, ... Journal of Thoracic Oncology 17 (9), S122-S123, 2022 | | 2022 |
Abstract B32: Mutant KRAS downregulates LIFR to enhance glycolysis in pancreatic cancer S Liu, HI Gandler, SR Walker, DQ Ye, ZT Giaccone, JA Nowak, AJ Aguirre, ... Cancer Research 79 (24_Supplement), B32-B32, 2019 | | 2019 |