Inborn errors of type I IFN immunity in patients with life-threatening COVID-19 Q Zhang, P Bastard, Z Liu, J Le Pen, M Moncada-Velez, J Chen, M Ogishi, ... Science 370 (6515), eabd4570, 2020 | 2139 | 2020 |
Heterozygous STAT1 gain-of-function mutations underlie an unexpectedly broad clinical phenotype J Toubiana, S Okada, J Hiller, M Oleastro, M Lagos Gomez, ... Blood, The Journal of the American Society of Hematology 127 (25), 3154-3164, 2016 | 491 | 2016 |
Autoantibodies neutralizing type I IFNs are present in~ 4% of uninfected individuals over 70 years old and account for~ 20% of COVID-19 deaths P Bastard, A Gervais, T Le Voyer, J Rosain, Q Philippot, J Manry, ... Science immunology 6 (62), eabl4340, 2021 | 441 | 2021 |
Multisystem inflammatory syndrome in children related to COVID-19: a systematic review L Hoste, R Van Paemel, F Haerynck European journal of pediatrics 180, 2019-2034, 2021 | 428 | 2021 |
X-linked recessive TLR7 deficiency in~ 1% of men under 60 years old with life-threatening COVID-19 T Asano, B Boisson, F Onodi, D Matuozzo, M Moncada-Velez, ... Science immunology 6 (62), eabl4348, 2021 | 333 | 2021 |
The risk of COVID-19 death is much greater and age dependent with type I IFN autoantibodies J Manry, P Bastard, A Gervais, T Le Voyer, J Rosain, Q Philippot, ... Proceedings of the National Academy of Sciences 119 (21), 2022 | 128 | 2022 |
Effect of anti-interleukin drugs in patients with COVID-19 and signs of cytokine release syndrome (COV-AID): a factorial, randomised, controlled trial J Declercq, KFA Van Damme, E De Leeuw, B Maes, C Bosteels, ... The Lancet Respiratory Medicine 9 (12), 1427-1438, 2021 | 105 | 2021 |
TIM3+ TRBV11-2 T cells and IFNγ signature in patrolling monocytes and CD16+ NK cells delineate MIS-C L Hoste, L Roels, L Naesens, V Bosteels, S Vanhee, S Dupont, ... Journal of Experimental Medicine 219 (2), 2022 | 65 | 2022 |
Case report: convalescent plasma, a targeted therapy for patients with CVID and severe COVID-19 KFA Van Damme, S Tavernier, N Van Roy, E De Leeuw, J Declercq, ... Frontiers in immunology 11, 596761, 2020 | 54 | 2020 |
Evaluation of humoral and cellular responses in SARS-CoV-2 mRNA vaccinated immunocompromised patients M Oyaert, MA De Scheerder, S Van Herrewege, G Laureys, S Van Assche, ... Frontiers in immunology 13, 858399, 2022 | 52 | 2022 |
Essentials in saline pharmacology for nasal or respiratory hygiene in times of COVID-19 S Huijghebaert, L Hoste, G Vanham European journal of clinical pharmacology 77, 1275-1293, 2021 | 47 | 2021 |
A CARD9 Founder Mutation Disrupts NF-κB Signaling by Inhibiting BCL10 and MALT1 Recruitment and Signalosome Formation M De Bruyne, L Hoste, DJ Bogaert, L Van den Bossche, SJ Tavernier, ... Frontiers in Immunology 9, 2366, 2018 | 36 | 2018 |
Immunoglobulin, glucocorticoid, or combination therapy for multisystem inflammatory syndrome in children: a propensity-weighted cohort study S Channon-Wells, O Vito, AJ McArdle, EG Seaby, H Patel, P Shah, ... The Lancet Rheumatology 5 (4), e184-e199, 2023 | 20 | 2023 |
Severe acute respiratory syndrome coronavirus 2 vaccination in children with a history of multisystem inflammatory syndrome in children: an international survey L Hoste, A Soriano-Arandes, EP Buddingh, E Whittaker, A Belot, ... The Journal of Pediatrics 248, 114-118, 2022 | 18* | 2022 |
MultiNicheNet: a flexible framework for differential cell-cell communication analysis from multi-sample multi-condition single-cell transcriptomics data R Browaeys, J Gilis, C Sang-Aram, P De Bleser, L Hoste, SJ Tavernier, ... BioRxiv, 2023.06. 13.544751, 2023 | 16 | 2023 |
Loss of GM-CSF-dependent instruction of alveolar macrophages in COVID-19 provides a rationale for inhaled GM-CSF treatment C Bosteels, KFA Van Damme, E De Leeuw, J Declercq, B Maes, ... Cell Reports Medicine 3 (12), 2022 | 16 | 2022 |
Mutations in RNU7-1 Weaken Secondary RNA Structure, Induce MCP-1 and CXCL10 in CSF, and Result in Aicardi-Goutières Syndrome with Severe End-Organ … L Naesens, J Nemegeer, F Roelens, L Vallaeys, M Meuwissen, ... Journal of clinical immunology 42 (5), 962-974, 2022 | 9 | 2022 |
Plasma C3d levels as a diagnostic marker for complete complement factor I deficiency L Naesens, J Smet, SJ Tavernier, P Schelstraete, L Hoste, S Lambrecht, ... Journal of Allergy and Clinical Immunology 147 (2), 749-753. e2, 2021 | 7 | 2021 |
Ranitidine-induced thrombocytopenia in a neonate–a case report and review of literature L Hoste, I George The Journal of Pediatric Pharmacology and Therapeutics 24 (1), 66-71, 2019 | 7 | 2019 |
COVID-19 vaccination in patients with primary immunodeficiencies: an international survey on patient vaccine hesitancy and self-reported adverse events M Pergent, F Haerynck, L Hoste, A Gardulf Frontiers in Immunology 14, 1166198, 2023 | 3 | 2023 |