The metabolic effects of GDF15 are mediated by the orphan receptor GFRAL PJ Emmerson, F Wang, Y Du, Q Liu, RT Pickard, MD Gonciarz, T Coskun, ... Nature medicine 23 (10), 1215-1219, 2017 | 510 | 2017 |
Treating diabetes and obesity with an FGF21-mimetic antibody activating the βKlotho/FGFR1c receptor complex IN Foltz, S Hu, C King, X Wu, C Yang, W Wang, J Weiszmann, J Stevens, ... Science translational medicine 4 (162), 162ra153-162ra153, 2012 | 234 | 2012 |
FGF19-induced hepatocyte proliferation is mediated through FGFR4 activation X Wu, H Ge, B Lemon, S Vonderfecht, J Weiszmann, R Hecht, J Gupte, ... Journal of Biological Chemistry 285 (8), 5165-5170, 2010 | 222 | 2010 |
The neuronal PAS domain protein 3 transcription factor controls FGF-mediated adult hippocampal neurogenesis in mice AA Pieper, X Wu, TW Han, SJ Estill, Q Dang, LC Wu, S Reece-Fincanon, ... Proceedings of the National Academy of Sciences 102 (39), 14052-14057, 2005 | 214 | 2005 |
Behavioral and regulatory abnormalities in mice deficient in the NPAS1 and NPAS3 transcription factors C Erbel-Sieler, C Dudley, Y Zhou, X Wu, SJ Estill, T Han, R Diaz-Arrastia, ... Proceedings of the National Academy of Sciences 101 (37), 13648-13653, 2004 | 203 | 2004 |
Co-receptor requirements for fibroblast growth factor-19 signaling X Wu, H Ge, J Gupte, J Weiszmann, G Shimamoto, J Stevens, N Hawkins, ... Journal of Biological Chemistry 282 (40), 29069-29072, 2007 | 170 | 2007 |
GDF15 and growth control PJ Emmerson, KL Duffin, S Chintharlapalli, X Wu Frontiers in physiology 9, 1712, 2018 | 164 | 2018 |
Inhibition of lipolysis may contribute to the acute regulation of plasma FFA and glucose by FGF21 in ob/ob mice X Li, H Ge, J Weiszmann, R Hecht, Y Li, MM Véniant, J Xu, X Wu, ... FEBS letters 583 (19), 3230-3234, 2009 | 134 | 2009 |
Separating mitogenic and metabolic activities of fibroblast growth factor 19 (FGF19) X Wu, H Ge, B Lemon, S Vonderfecht, H Baribault, J Weiszmann, J Gupte, ... Proceedings of the National Academy of Sciences 107 (32), 14158-14163, 2010 | 133 | 2010 |
C-terminal tail of FGF19 determines its specificity toward Klotho co-receptors X Wu, B Lemon, XF Li, J Gupte, J Weiszmann, J Stevens, N Hawkins, ... Journal of biological chemistry 283 (48), 33304-33309, 2008 | 127 | 2008 |
Selective activation of FGFR4 by an FGF19 variant does not improve glucose metabolism in ob/ob mice X Wu, H Ge, B Lemon, J Weiszmann, J Gupte, N Hawkins, X Li, J Tang, ... Proceedings of the National Academy of Sciences 106 (34), 14379-14384, 2009 | 121 | 2009 |
Signaling property study of adhesion G-protein-coupled receptors J Gupte, G Swaminath, J Danao, H Tian, Y Li, X Wu FEBS letters 586 (8), 1214-1219, 2012 | 119 | 2012 |
Enzymatic deglycation of proteins X Wu, VM Monnier Archives of biochemistry and biophysics 419 (1), 16-24, 2003 | 109 | 2003 |
Protein aging by carboxymethylation of lysines generates sites for divalent metal and redox active copper binding: relevance to diseases of glycoxidative stress AK Saxena, P Saxena, X Wu, M Obrenovich, MF Weiss, VM Monnier Biochemical and biophysical research communications 260 (2), 332-338, 1999 | 101 | 1999 |
Dual actions of fibroblast growth factor 19 on lipid metabolism [S] X Wu, H Ge, H Baribault, J Gupte, J Weiszmann, B Lemon, J Gardner, ... Journal of lipid research 54 (2), 325-332, 2013 | 79 | 2013 |
FGF21 can be mimicked in vitro and in vivo by a novel anti-FGFR1c/β-Klotho bispecific protein R Smith, A Duguay, A Bakker, P Li, J Weiszmann, MR Thomas, BM Alba, ... PloS one 8 (4), e61432, 2013 | 71 | 2013 |
Chimeric polypeptides and uses thereof Y Li, X Wu, Z Wang US Patent 8,324,160, 2012 | 66 | 2012 |
Cloning of Amadoriase I Isoenzyme from Aspergillus sp.: Evidence of FAD Covalently Linked to Cys342, X Wu, M Takahashi, SG Chen, VM Monnier Biochemistry 39 (6), 1515-1521, 2000 | 59 | 2000 |
Trefoil factor 3 (TFF3) is regulated by food intake, improves glucose tolerance and induces mucinous metaplasia H Ge, J Gardner, X Wu, I Rulifson, J Wang, Y Xiong, J Ye, E Belouski, ... PloS one 10 (6), e0126924, 2015 | 51 | 2015 |
Characterization of a FGF19 variant with altered receptor specificity revealed a central role for FGFR1c in the regulation of glucose metabolism H Ge, H Baribault, S Vonderfecht, B Lemon, J Weiszmann, J Gardner, ... PLoS One 7 (3), e33603, 2012 | 44 | 2012 |