Dissection of the BCR-ABL signaling network using highly specific monobody inhibitors to the SHP2 SH2 domains F Sha, EB Gencer, S Georgeon, A Koide, N Yasui, S Koide, O Hantschel Proceedings of the National Academy of Sciences 110 (37), 14924-14929, 2013 | 103 | 2013 |
Mechanisms of resistance to BCR-ABL and other kinase inhibitors AJ Lamontanara, EB Gencer, O Kuzyk, O Hantschel Biochimica et Biophysica Acta (BBA)-Proteins and Proteomics 1834 (7), 1449-1459, 2013 | 80 | 2013 |
Mechanisms responsible for nilotinib resistance in human chronic myeloid leukemia cells and reversal of resistance A Camgoz, EB Gencer, AU Ural, Y Baran Leukemia & lymphoma 54 (6), 1279-1287, 2013 | 62 | 2013 |
A novel mechanism of dasatinib-induced apoptosis in chronic myeloid leukemia; ceramide synthase and ceramide clearance genes EB Gencer, AU Ural, F Avcu, Y Baran Annals of hematology 90, 1265-1275, 2011 | 61 | 2011 |
Roles of ceramide synthase and ceramide clearence genes in nilotinib-induced cell death in chronic myeloidleukemia cells A Camgoz, EB Gencer, AU Ural, F Avcu, Y Baran Leukemia & lymphoma 52 (8), 1574-1584, 2011 | 27 | 2011 |
Ethacrynic acid and cinnamic acid combination exhibits selective anticancer effects on K562 chronic myeloid leukemia cells M Yenigül, İ Akçok, EB Gencer Akçok Molecular Biology Reports 49 (8), 7521-7530, 2022 | 8 | 2022 |
Histone deacetylase inhibition and autophagy modulation induces a synergistic antiproliferative effect and cell death in cholangiocarcinoma cells M Yenigul, EB Gencer Akçok ACS omega 8 (24), 21755-21768, 2023 | 3 | 2023 |
A novel mechanism of nilotinib-induced apoptosis; bioactive sphingolipids Y Baran, A Camgöz, E Gençer, A Ural, F Avcu Haematologica, 2010 | 2 | 2010 |
The therapeutic potential of targeting HDAC6 with Tubastatin A in TFK-1 and EGI-1 cholangiocarcinoma cells M Yenigül, EG Akcok Cumhuriyet Science Journal 42 (4), 775-780, 2021 | 1 | 2021 |
Determination of promising inhibitors for N-SH2 domain of SHP2 tyrosine phosphatase: an in silico study EB Gencer Akçok, H Güner, İ Akçok Molecular Diversity, 1-15, 2024 | | 2024 |
Measurement of Autophagic Activity in Cancer Cells with Flow Cytometric Analysis Using Cyto-ID Staining M Şansaçar, EB Gencer Akçok | | 2024 |
Inhibition of PI3K-AKT-mTOR pathway and modulation of histone deacetylase enzymes reduce the growth of acute myeloid leukemia cells M Şansaçar, H Sağır, EB Gencer Akçok Medical Oncology 41 (1), 31, 2023 | | 2023 |
Cytotoxic and Cytostatic Effects of Targeting mTOR and Hedgehog Pathways in Acute Myeloid Leukemia E Cicek, FM KÜÇÜKTAŞ, M YENİGÜL, EG AKCOK Experimed 12 (3), 202-208, 2022 | | 2022 |
Poster: AML-240: Investigation of the Antitumor Effect of Targeting PI3K-AKT-mTOR Pathway and Histone Deacetylase Enzymes on Acute Myeloid Leukemia Cells M Sansacar, H Sagir, EG Akcok Clinical Lymphoma Myeloma and Leukemia 21, S214, 2021 | | 2021 |
AML-240: Investigation of the Antitumor Effect of Targeting PI3K-AKT-mTOR Pathway and Histone Deacetylase Enzymes on Acute Myeloid Leukemia Cells M Sansacar, H Sagir, EG Akcok Clinical Lymphoma Myeloma and Leukemia 21, S294, 2021 | | 2021 |
Functional Perturbation of the Gab2 Multiprotein Complex by High-affinity SH2-binding Monobodies in Chronic Myelogenous Leukemia G Akçok, E Başak EPFL, 2015 | | 2015 |
Increasing chemosensitivity of chronic myeloid leukemia cells to dasatinib by targeting bioactive sphingolipids EB Gencer PQDT-Global, 2010 | | 2010 |
Therapeutic potential of targeting sphingolipid signaling pathways in various types of cancers Y Baran, EY Başsoy, Z Çakır, A Camgöz, EB Gencer, M Kartal, G Can, ... ejc supplements, 2010 | | 2010 |
A Novel Mechanism of Nilotinib-Induced Apoptosis; Sphingolipids. Y Baran, EB Gencer, A Camgoz, F Avcu, AU Ural Blood 114 (22), 4246, 2009 | | 2009 |
Accumulation of apoptotic ceramides increased apoptotic effects of nilotinib in Philadelphia positive MEG-01 cells synergistically Y Baran, EB Gençer, AU Ural, F Avcu Haematologica, 2009 | | 2009 |