Regulation of organic anion transporting polypeptides (OATP) 1B1-and OATP1B3-mediated transport: an updated review in the context of OATP-mediated drug-drug interactions K Alam, A Crowe, X Wang, P Zhang, K Ding, L Li, W Yue International journal of molecular sciences 19 (3), 855, 2018 | 95 | 2018 |
In vitro antimicrobial activities of four medicinally important plants in Bangladesh MR Islam, R Ahamed, MO Rahman, MA Akbar, M Al-Amin, KD Alam, ... Eur J Sci Res 39 (Suppl 2), 199-206, 2010 | 69 | 2010 |
Pretreatment with rifampicin and tyrosine kinase inhibitor dasatinib potentiates the inhibitory effects toward OATP1B1-and OATP1B3-mediated transport S Pahwa, K Alam, A Crowe, T Farasyn, S Neuhoff, O Hatley, K Ding, ... Journal of pharmaceutical sciences 106 (8), 2123-2135, 2017 | 61 | 2017 |
In vitro antimicrobial activities of different fractions of Swertia chirata ethanolic extract. KD Alam, MS Ali, S Parvin, S Mahjabeen, MA Akbar, R Ahamed Pakistan journal of biological sciences: PJBS 12 (19), 1334-1337, 2009 | 41 | 2009 |
Downregulation of organic anion transporting polypeptide (OATP) 1B1 transport function by lysosomotropic drug chloroquine: implication in OATP-mediated drug-drug interactions K Alam, S Pahwa, X Wang, P Zhang, K Ding, AH Abuznait, L Li, W Yue Molecular pharmaceutics 13 (3), 839-851, 2016 | 40 | 2016 |
Characterization of plasma membrane localization and phosphorylation status of organic anion transporting polypeptide (OATP) 1B1 c. 521 T> C nonsynonymous single-nucleotide … A Crowe, W Zheng, J Miller, S Pahwa, K Alam, KM Fung, E Rubin, F Yin, ... Pharmaceutical research 36, 1-18, 2019 | 37 | 2019 |
Preincubation with everolimus and sirolimus reduces organic anion-transporting polypeptide (OATP) 1B1-and 1B3-mediated transport independently of mTOR kinase inhibition … T Farasyn, A Crowe, O Hatley, S Neuhoff, K Alam, J Kanyo, TKT Lam, ... Journal of pharmaceutical sciences 108 (10), 3443-3456, 2019 | 28 | 2019 |
Treatment with proteasome inhibitor bortezomib decreases organic anion transporting polypeptide (OATP) 1B3-mediated transport in a substrate-dependent manner K Alam, T Farasyn, A Crowe, K Ding, W Yue PLoS One 12 (11), e0186924, 2017 | 28 | 2017 |
Physiologically‐based pharmacokinetic modeling to support determination of bioequivalence for dermatological drug products: scientific and regulatory considerations E Tsakalozou, K Alam, A Babiskin, L Zhao Clinical Pharmacology & Therapeutics 111 (5), 1036-1049, 2022 | 26 | 2022 |
Potential hypoglycemic effect of Swertia chirayita—An Indian subcontinent herb with important medicinal value KD Alam, MS Ali, S Mahjabeen, MR Hassan, MF Rahman, R Chowdhury Pharmacologyonline 2, 642-647, 2011 | 26 | 2011 |
In vitro cytotoxic properties of ethanolic extracts of various parts of Swietenia mahagoni MA Akbar, R Ahamed, KD Alam, MS Ali European Journal of Scientific Research 32 (4), 541-544, 2009 | 22 | 2009 |
Analgesic activities of ethanol extract of leaf, stem and their different fractions of Swertia chirata KD Alam, MS Ali, S Mahjabeen, S Parvin, MA Akbar, R Ahamed Pakistan journal of pharmaceutical sciences 23 (4), 455-458, 2010 | 21 | 2010 |
Characterization of liver-and cancer-type-organic anion transporting polypeptide (OATP) 1B3 messenger RNA expression in normal and cancerous human tissues K Alam, T Farasyn, K Ding, W Yue Drug metabolism letters 12 (1), 24-32, 2018 | 20 | 2018 |
Assessing OATP1B1-and OATP1B3-mediated drug-drug interaction potential of vemurafenib using R-value and physiologically-based pharmacokinetic models R Kayesh, T Farasyn, A Crowe, Q Liu, S Pahwa, K Alam, S Neuhoff, ... Journal of pharmaceutical sciences 110 (1), 314-324, 2021 | 16 | 2021 |
Multi‐phase multi‐layer mechanistic dermal absorption (MPML MechDermA) model to predict local and systemic exposure of drug products applied on skin N Patel, JF Clarke, F Salem, T Abdulla, F Martins, S Arora, E Tsakalozou, ... CPT: Pharmacometrics & Systems Pharmacology 11 (8), 1060-1084, 2022 | 11 | 2022 |
Mechanistic modeling of in vitro skin permeation and extrapolation to in vivo for topically applied metronidazole drug products using a physiologically based pharmacokinetic model S Arora, J Clarke, E Tsakalozou, P Ghosh, K Alam, JE Grice, MS Roberts, ... Molecular Pharmaceutics 19 (9), 3139-3152, 2022 | 6 | 2022 |
Amphotericin B release rate is the link between drug status in the liposomal bilayer and toxicity Y Svirkin, J Lee, R Marx, S Yoon, N Landrau, MA Kaisar, B Qin, JH Park, ... Asian Journal of Pharmaceutical Sciences 17 (4), 544-556, 2022 | 4 | 2022 |
Free radical scavenging potential of methanol extract of Smilax roxburghiana MR Hasan, KD Alam, S Mahjabeen, MF Rahman, N Akter, MU Bushra Pharmacologyonline 2, 774-783, 2011 | 4 | 2011 |
In vitro binding chemistry of Amlodipine Besylate (Calcium Channel Blocker) and Atorvastatin Calcium (HMG-CoA Reductase Inhibitor) to serum albumin and their mutual effect to … KD Alam, MK Hosain, S Kabir, R Chowdhury, S Mehjabeen, MS Mondal, ... Am. J. Drug Discov. Dev 1 (4), 220-230, 2011 | 4 | 2011 |
Mechanistic modeling of ophthalmic, nasal, injectable, and implant generic drug products: a workshop summary report ML Tan, S Chandran, R Jereb, K Alam, R Bies, D Kozak, R Walenga, ... CPT: Pharmacometrics & Systems Pharmacology 12 (5), 631-638, 2023 | 2 | 2023 |