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Samantha B Bremner
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Incorporation of sensing modalities into de novo designed fluorescence-activating proteins
JC Klima, LA Doyle, JD Lee, M Rappleye, LA Gagnon, MY Lee, EP Barros, ...
Nature Communications 12 (1), 856, 2021
392021
Identification of variable lymphocyte receptors that can target therapeutics to pathologically exposed brain extracellular matrix
BJ Umlauf, PA Clark, JM Lajoie, JV Georgieva, S Bremner, BR Herrin, ...
Science advances 5 (5), eaau4245, 2019
232019
Full-length dystrophin deficiency leads to contractile and calcium transient defects in human engineered heart tissues
SB Bremner, CJ Mandrycky, A Leonard, RM Padgett, AR Levinson, ...
Journal of Tissue Engineering 13, 20417314221119628, 2022
162022
A Change of Heart: Human Cardiac Tissue Engineering as a Platform for Drug Development
SB Bremner, KS Gaffney, NJ Sniadecki, DL Mack
Current Cardiology Reports 24 (5), 473-486, 2022
132022
Engineered heart tissues for contractile, structural, and transcriptional assessment of human pluripotent stem cell-derived cardiomyocytes in a three-dimensional, auxotonic …
S Bremner, AJ Goldstein, T Higashi, NJ Sniadecki
Cardiac Tissue Engineering: Methods and Protocols, 87-97, 2022
52022
Structure-guided engineering of a fast genetically encoded sensor for real-time H2O2 monitoring
JD Lee, W Won, K Kimball, Y Wang, F Yeboah, KM Evitts, C Neiswanger, ...
bioRxiv, 2024
32024
A yeast display immunoprecipitation screen for targeted discovery of antibodies against membrane protein complexes
JM Lajoie, YK Cho, D Frost, S Bremner, L Li, EV Shusta
Protein Engineering, Design and Selection 32 (5), 219-230, 2019
32019
Multi-scale models reveal hypertrophic cardiomyopathy MYH7 G256E mutation drives hypercontractility and elevated mitochondrial respiration
S Lee, AS Vander Roest, C Blair, K Kao, SB Bremner, MC Childers, ...
bioRxiv, 2023.06. 08.544276, 2023
12023
Incomplete-penetrant hypertrophic cardiomyopathy MYH7 G256E mutation causes hypercontractility and elevated mitochondrial respiration
S Lee, AS Vander Roest, CA Blair, K Kao, SB Bremner, MC Childers, ...
Proceedings of the National Academy of Sciences 121 (19), e2318413121, 2024
2024
Far-red and sensitive sensor for monitoring real time H2O2 dynamics with subcellular resolution and in multi-parametric imaging applications.
A Berndt, J Lee, A Nguyen, Z Jin, A Moghadasi, C Gibbs, S Wait, K Evitts, ...
2024
Ultra-fast genetically encoded sensor for precise real-time monitoring of physiological and pathophysiological peroxide dynamics
A Berndt, J Lee, W Won, K Kimball, C Neiswanger, S Schattauer, Y Wang, ...
2024
Far-red and sensitive sensor for monitoring real-time H2O2 dynamics with subcellular resolution and in multi-parametric imaging applications.
JD Lee, A Nguyen, ZR Jin, A Moghadasi, CE Gibbs, SJ Wait, KM Evitts, ...
bioRxiv, 2024.02. 06.579232, 2024
2024
Human Engineered Heart Tissues as an In Vitro Model of Duchenne Muscular Dystrophy
S Bremner
University of Washington, 2022
2022
SCIDOT-05. DEVELOPING VARIABLE LYMPHOCYTE RECEPTORS THAT TARGET PATHOLOGICALLY EXPOSED NEURAL ECM TO TREAT GLIOBLASTOMA
B J Umlauf, P A Clark, J M Lajoie, J V Georgieva, S Bremner, B R Herrin, ...
Neuro-Oncology 21 (Supplement_6), vi273-vi273, 2019
2019
EXTH-67. IDENTIFICATION AND DEVELOPMENT OF NEURAL ECM-BINDING LAMPREY ANTIBODIES (VARIABLE LYMPHOCYTE RECEPTORS) THAT TARGET GLIOBLASTOMA
B Umlauf, P Clark, J Lajoie, J Georgieva, S Bremner, B Herrin, E Shusta, ...
Neuro-Oncology 21 (Suppl 6), vi96, 2019
2019
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