Human beta cell mass and function in diabetes: Recent advances in knowledge and technologies to understand disease pathogenesis C Chen, CM Cohrs, J Stertmann, R Bozsak, S Speier Molecular metabolism 6 (9), 943-957, 2017 | 544 | 2017 |
Dysfunction of persisting β cells is a key feature of early type 2 diabetes pathogenesis CM Cohrs, JK Panzer, DM Drotar, SJ Enos, N Kipke, C Chen, R Bozsak, ... Cell reports 31 (1), 2020 | 129 | 2020 |
Vessel Network Architecture of Adult Human Islets Promotes Distinct Cell-Cell Interactions In Situ and Is Altered After Transplantation CM Cohrs, C Chen, SR Jahn, J Stertmann, H Chmelova, J Weitz, A Bähr, ... Endocrinology 158 (5), 1373-1385, 2017 | 89 | 2017 |
Alterations in β-cell calcium dynamics and efficacy outweigh islet mass adaptation in compensation of insulin resistance and prediabetes onset C Chen, H Chmelova, CM Cohrs, JA Chouinard, SR Jahn, J Stertmann, ... Diabetes 65 (9), 2676-2685, 2016 | 85 | 2016 |
Exendin-4 protects hypoxic islets from oxidative stress and improves islet transplantation outcome M Padmasekar, N Lingwal, B Samikannu, C Chen, H Sauer, T Linn Endocrinology 154 (4), 1424-1433, 2013 | 68 | 2013 |
Distinct roles of β-cell mass and function during type 1 diabetes onset and remission H Chmelova, CM Cohrs, JA Chouinard, C Petzold, M Kuhn, C Chen, ... Diabetes 64 (6), 2148-2160, 2015 | 60 | 2015 |
Improved intraportal islet transplantation outcome by systemic IKK-beta inhibition: NF-κB activity in pancreatic islets depends on oxygen availability C Chen, R Moreno, B Samikannu, RG Bretzel, ML Schmitz, T Linn American Journal of Transplantation 11 (2), 215-224, 2011 | 36 | 2011 |
Dipeptidyl peptidase IV inhibition activates CREB and improves islet vascularization through VEGF-A/VEGFR-2 signaling pathway B Samikannu, C Chen, N Lingwal, M Padmasekar, FB Engel, T Linn PLoS One 8 (12), e82639, 2013 | 33 | 2013 |
Activation of NFκB dependent apoptotic pathway in pancreatic islet cells by hypoxia Y Lai, H Brandhorst, H Hossain, A Bierhaus, C Chen, RG Bretzel, T Linn Islets 1 (1), 19-25, 2009 | 33 | 2009 |
Magnesium lithospermate B ameliorates renal cortical microperfusion in rats1 C CHEN, Y WANG Acta Pharmacologica Sinica 27 (2), 217-222, 2006 | 33 | 2006 |
Genetic modification of cells for transplantation Y Lai, I Drobinskaya, E Kolossov, C Chen, T Linn Advanced Drug Delivery Reviews 60 (2), 146-159, 2008 | 32 | 2008 |
The biomechanical properties of an epithelial tissue determine the location of its vasculature M Kragl, R Schubert, H Karsjens, S Otter, B Bartosinska, K Jeruschke, ... Nature communications 7 (1), 13560, 2016 | 22 | 2016 |
Innate immunity and heat shock response in islet transplantation Y Lai, C Chen, T Linn Clinical & Experimental Immunology 157 (1), 1-8, 2009 | 20 | 2009 |
Wnt4 is heterogeneously activated in maturing β-cells to control calcium signaling, metabolism and function K Katsumoto, S Yennek, C Chen, LFD Silva, S Traikov, D Sever, A Azad, ... Nature communications 13 (1), 6255, 2022 | 16 | 2022 |
Anti-inflammatory thalidomide improves islet grafts survival and functions in a xenogenic environment C Chen, C Kuehn, RG Bretzel, T Linn PLoS One 4 (7), e6312, 2009 | 16 | 2009 |
Bridging the gap: pancreas tissue slices from organ and tissue donors for the study of diabetes pathogenesis CM Cohrs, C Chen, MA Atkinson, DM Drotar, S Speier Diabetes 73 (1), 11-22, 2024 | 7 | 2024 |
Transplantation of islets of langerhans into the anterior chamber of the eye for longitudinal in vivo imaging CM Cohrs, C Chen, S Speier Animal Models of Diabetes: Methods and Protocols, 149-157, 2020 | 4 | 2020 |
Mechanisms of age-dependent amplification of insulin secretion C Henke, C Chen, SR Bornstein, R de Cabo, S Speier, AL Birkenfeld DIABETOLOGIA 62, S219-S220, 2019 | | 2019 |
High-purity magnesium lithospermate B and preparation method therefor L Xuan, Y Wang, S Weibin, C Chen, D Li, X Zhou, Y Gu, L Hu, J Zhao, ... US Patent 10,259,798, 2019 | | 2019 |