A unified model for apical caspase activation KM Boatright, M Renatus, FL Scott, S Sperandio, H Shin, IM Pedersen, ... Molecular cell 11 (2), 529-541, 2003 | 1362 | 2003 |
Structural basis for the inhibition of caspase-3 by XIAP SJ Riedl, M Renatus, R Schwarzenbacher, Q Zhou, C Sun, SW Fesik, ... Cell 104 (5), 791-800, 2001 | 1095 | 2001 |
Dimer formation drives the activation of the cell death protease caspase 9 M Renatus, HR Stennicke, FL Scott, RC Liddington, GS Salvesen Proceedings of the National Academy of Sciences 98 (25), 14250-14255, 2001 | 637 | 2001 |
Structural basis for the activation of flaviviral NS3 proteases from dengue and West Nile virus P Erbel, N Schiering, A D'Arcy, M Renatus, M Kroemer, SP Lim, Z Yin, ... Nature structural & molecular biology 13 (4), 372-373, 2006 | 636 | 2006 |
Crystal structure of the anthrax lethal factor AD Pannifer, TY Wong, R Schwarzenbacher, M Renatus, C Petosa, ... Nature 414 (6860), 229-233, 2001 | 567 | 2001 |
XIAP inhibits caspase‐3 and‐7 using two binding sites: evolutionarily conserved mechanism of IAPs FL Scott, JB Denault, SJ Riedl, H Shin, M Renatus, GS Salvesen The EMBO journal 24 (3), 645-655, 2005 | 528 | 2005 |
Internally quenched fluorescent peptide substrates disclose the subsite preferences of human caspases 1, 3, 6, 7 and 8 HR Stennicke, M RENATUS, M MELDAL, GS SALVESEN Biochemical Journal 350 (2), 563-568, 2000 | 376 | 2000 |
Structural basis for the activation of human procaspase-7 SJ Riedl, P Fuentes-Prior, M Renatus, N Kairies, S Krapp, R Huber, ... Proceedings of the National Academy of Sciences 98 (26), 14790-14795, 2001 | 287 | 2001 |
Structural basis of ubiquitin recognition by the deubiquitinating protease USP2 M Renatus, SG Parrado, A D'Arcy, U Eidhoff, B Gerhartz, U Hassiepen, ... Structure 14 (8), 1293-1302, 2006 | 235 | 2006 |
Crystal structure of the human COP9 signalosome GM Lingaraju, RD Bunker, S Cavadini, D Hess, U Hassiepen, M Renatus, ... Nature 512 (7513), 161-165, 2014 | 233 | 2014 |
Apoptosome: the seven-spoked death machine GS Salvesen, M Renatus Developmental Cell 2 (3), 256-257, 2002 | 149 | 2002 |
Targeted inhibition of the COP9 signalosome for treatment of cancer A Schlierf, E Altmann, J Quancard, AB Jefferson, R Assenberg, M Renatus, ... Nature communications 7 (1), 13166, 2016 | 141 | 2016 |
Lysine 156 promotes the anomalous proenzyme activity of tPA: X-ray crystal structure of single-chain human tPA M Renatus, RA Engh, MT Stubbs, R Huber, S Fischer, U Kohnert, W Bode The EMBO journal 16 (16), 4797-4805, 1997 | 141 | 1997 |
Structural and functional analyses of benzamidine-based inhibitors in complex with trypsin: implications for the inhibition of factor Xa, tPA, and urokinase M Renatus, W Bode, R Huber, J Stuerzebecher, MT Stubbs Journal of medicinal chemistry 41 (27), 5445-5456, 1998 | 134 | 1998 |
Structural determinants of MALT1 protease activity C Wiesmann, L Leder, J Blank, A Bernardi, S Melkko, A Decock, A D'Arcy, ... Journal of molecular biology 419 (1-2), 4-21, 2012 | 99 | 2012 |
Structural mapping of the active site specificity determinants of human tissue-type plasminogen activator: implications for the design of low molecular weight substrates and … M Renatus, W Bode, R Huber, J Stürzebecher, D Prasa, S Fischer, ... Journal of Biological Chemistry 272 (35), 21713-21719, 1997 | 87 | 1997 |
The BIR domain of IAP-like protein 2 is conformationally unstable: implications for caspase inhibition H Shin, M Renatus, BP Eckelman, VA Nunes, CAM Sampaio, ... Biochemical Journal 385 (1), 1-10, 2005 | 84 | 2005 |
3-Amidinophenylalanine-based inhibitors of urokinase J Stürzebecher, H Vieweg, T Steinmetzer, A Schweinitz, MT Stubbs, ... Bioorganic & medicinal chemistry letters 9 (21), 3147-3152, 1999 | 82 | 1999 |
Crystal structure of the apoptotic suppressor CrmA in its cleaved form M Renatus, Q Zhou, HR Stennicke, SJ Snipas, D Turk, LA Bankston, ... Structure 8 (7), 789-797, 2000 | 64 | 2000 |
Solution structure of PMP-C: a new fold in the group of small serine proteinase inhibitors G Mer, H Hietter, C Kellenberger, M Renatus, B Luu, JF Lefevre Journal of molecular biology 258 (1), 158-171, 1996 | 62 | 1996 |