| Orthogonal optical control of a G protein-coupled receptor with a SNAP-tethered photochromic ligand J Broichhagen, A Damijonaitis, J Levitz, KR Sokol, P Leippe, D Konrad, ... ACS central science 1 (7), 383-393, 2015 | 117 | 2015 |
| Synthesis of Photoswitchable Δ9-Tetrahydrocannabinol Derivatives Enables Optical Control of Cannabinoid Receptor 1 Signaling MV Westphal, MA Schafroth, RC Sarott, MA Imhof, CP Bold, P Leippe, ... Journal of the American Chemical Society 139 (50), 18206-18212, 2017 | 94 | 2017 |
| Dual optical control and mechanistic insights into photoswitchable group II and III metabotropic glutamate receptors J Levitz, J Broichhagen, P Leippe, D Konrad, D Trauner, EY Isacoff Proceedings of the National Academy of Sciences 114 (17), E3546-E3554, 2017 | 72 | 2017 |
| The RESOLUTE consortium: unlocking SLC transporters for drug discovery G Superti-Furga, D Lackner, T Wiedmer, A Ingles-Prieto, B Barbosa, ... Nature reviews Drug discovery 19 (7), 429-430, 2020 | 69 | 2020 |
| Oxidative approach enables efficient access to cyclic azobenzenes MS Maier, K Hüll, M Reynders, BS Matsuura, P Leippe, T Ko, ... Journal of the American Chemical Society 141 (43), 17295-17304, 2019 | 67 | 2019 |
| Specificity and speed: tethered photopharmacology P Leippe, J Koehler Leman, D Trauner Biochemistry 56 (39), 5214-5220, 2017 | 45 | 2017 |
| An overview of cell-based assay platforms for the solute carrier family of transporters V Dvorak, T Wiedmer, A Ingles-Prieto, P Altermatt, H Batoulis, F Bärenz, ... Frontiers in pharmacology 12, 722889, 2021 | 37 | 2021 |
| Designing azobenzene-based tools for controlling neurotransmission P Leippe, JA Frank Current Opinion in Structural Biology 57, 23-30, 2019 | 30 | 2019 |
| Photohormones enable optical control of the peroxisome proliferator-activated receptor γ (PPARγ) K Hinnah, S Willems, J Morstein, J Heering, FWW Hartrampf, ... Journal of Medicinal Chemistry 63 (19), 10908-10920, 2020 | 29 | 2020 |
| Conditional and reversible activation of class A and BG protein-coupled receptors using tethered pharmacology T Podewin, J Ast, J Broichhagen, NHF Fine, D Nasteska, P Leippe, ... ACS Central Science 4 (2), 166-179, 2018 | 26 | 2018 |
| Development of a photoswitchable antagonist of NMDA receptors FWW Hartrampf, DM Barber, K Gottschling, P Leippe, M Hollmann, ... Tetrahedron 73 (33), 4905-4912, 2017 | 24 | 2017 |
| Optical control of a delayed rectifier and a two-pore potassium channel with a photoswitchable bupivacaine P Leippe, N Winter, MP Sumser, D Trauner ACS Chemical Neuroscience 9 (12), 2886-2891, 2018 | 16 | 2018 |
| Transformation of receptor tyrosine kinases into glutamate receptors and photoreceptors P Leippe, J Broichhagen, K Cailliau, A Mougel, M Morel, C Dissous, ... Angewandte Chemie International Edition 59 (17), 6720-6723, 2020 | 14 | 2020 |
| Platform Reagents Enable Synthesis of Ligand-Directed Covalent Probes: Study of Cannabinoid Receptor 2 in Live Cells M Kosar, DA Sykes, AEG Viray, RM Vitale, RC Sarott, RL Ganzoni, ... Journal of the American Chemical Society 145 (28), 15094-15108, 2023 | 7 | 2023 |
| Engineering of a biosensor for intracellular aspartate L Hellweg, M Pfeifer, L Chang, M Tarnawski, A Bergner, J Kress, J Hiblot, ... bioRxiv, 2023.05. 04.537313, 2023 | 2 | 2023 |
| Tethered photopharmacology P Leippe lmu, 2018 | 1 | 2018 |
Dirk TraunerUniversity of PennsylvaniaVerified email at upenn.edu
