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Kelsey Nassar
Kelsey Nassar
Senior Scientist, Cogent Biosciences
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Cited by
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Year
Whole-exome sequencing identifies recurrent SF3B1 R625 mutation and comutation of NF1 and KIT in mucosal melanoma
JD Hintzsche, NT Gorden, CM Amato, J Kim, KE Wuensch, SE Robinson, ...
Melanoma research 27 (3), 189-199, 2017
1412017
The mutational landscape of mucosal melanoma
KW Nassar, AC Tan
Seminars in cancer biology 61, 139-148, 2020
1392020
MCL1 inhibitors S63845/MIK665 plus Navitoclax synergistically kill difficult-to-treat melanoma cells
N Mukherjee, J Skees, KJ Todd, DA West, KA Lambert, WA Robinson, ...
Cell death & disease 11 (6), 443, 2020
512020
Src-mediated regulation of the PI3K pathway in advanced papillary and anaplastic thyroid cancer
TC Beadnell, KW Nassar, MM Rose, EG Clark, BP Danysh, MC Hofmann, ...
Oncogenesis 7 (2), 23, 2018
442018
Targeting the NF-κB pathway as a combination therapy for advanced thyroid cancer
N Pozdeyev, A Berlinberg, Q Zhou, K Wuensch, H Shibata, WM Wood, ...
PloS one 10 (8), e0134901, 2015
392015
The mitogen-activated protein kinase pathway facilitates resistance to the src inhibitor dasatinib in thyroid cancer
TC Beadnell, KM Mishall, Q Zhou, SM Riffert, KE Wuensch, BE Kessler, ...
Molecular cancer therapeutics 15 (8), 1952-1963, 2016
312016
Targeting CDK4/6 Represents a Therapeutic Vulnerability in Acquired BRAF/MEK Inhibitor–Resistant Melanoma
KW Nassar, JD Hintzsche, SM Bagby, V Espinoza, C Langouët-Astrié, ...
Molecular cancer therapeutics 20 (10), 2049-2060, 2021
192021
Pre-treatment mutational and transcriptomic landscape of responding metastatic melanoma patients to anti-PD1 immunotherapy
CM Amato, JD Hintzsche, K Wells, A Applegate, NT Gorden, VM Vorwald, ...
Cancers 12 (7), 1943, 2020
192020
Trunk or branch? Identifying and targeting intratumoral heterogeneity in hepatocellular carcinoma using genomics and patient derived primary cancer cells
KE Wuensch, AC Tan
Translational Cancer Research 5 (Suppl 7), 2016
22016
Abstract PO3-26-01: Preclinical in vitro and in vivo characterization of a novel, wild-type-sparing, PI3Kα H1047R mutant-selective inhibitor
AC Smith, B Arwood-Levine, A Born, R Brizendine, P Chatterjee, ...
Cancer Research 84 (9_Supplement), PO3-26-01-PO3-26-01, 2024
2024
AKT-independent signaling in PIK3CA-mutant thyroid cancer mediates resistance to dual SRC and MEK1/2 inhibition
MM Rose, KW Nassar, V Sharma, RE Schweppe
Medical Oncology 40 (10), 299, 2023
2023
Chemokine Receptor 1 and its associated immune pathway are downregulated in SF3B1MT blood and non-blood cancers
M Dastpak, H Kim, CL Paraggio, CE Leonard, S Yin, B Chi, KW Nassar, ...
bioRxiv, 2022.03. 31.485699, 2022
2022
Defining Oncogenic Drivers in Therapy Resistant Melanoma and Rare Melanoma Subtypes
KW Nassar
University of Colorado Denver, Anschutz Medical Campus, 2021
2021
674 The effective killing of the difficult-to-treat melanomas with the combinations of MCL1 inhibitors S63845/MIK665 plus Navitoclax
N Mukherjee, J Skees, K Todd, D West, K Lambert, W Robinson, C Amato, ...
Journal of Investigative Dermatology 140 (7), S91, 2020
2020
Abstract B076: Uncoupling of the cell cycle pathway from the MAPK pathway in BRAF/MEK inhibitor resistant melanoma
KW Nassar, J Hintzsche, S Bagby, C Langouet-Astrie, J Samson, C Amato, ...
Molecular Cancer Therapeutics 18 (12_Supplement), B076-B076, 2019
2019
Targeting Hsp90 in Thyroid Cancer
K Wuensch, TC Beadnell, Q Zhou, KM Mishall, LA Pike, RE Schweppe
Thyroid Hormone Action, Cancer and Clinical Thyroid, THR-062-THR-062, 2015
2015
The NF-kappa b Pathway Is Activated By Chemotherapy and Radiation in Thyroid Cancer
N Pozdeyev, WM Wood, LA Pike, K Wuensch, H Shibata, BR Haugen
ENDOCRINE REVIEWS 35 (3), 2014
2014
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