| Amplification of the neu/erbB-2 oncogene in a mouse model of mammary tumorigenesis ER Andrechek, WR Hardy, PM Siegel, MA Rudnicki, RD Cardiff, ... Proceedings of the National Academy of Sciences 97 (7), 3444-3449, 2000 | 321 | 2000 |
| Temporal regulation of EGF signalling networks by the scaffold protein Shc1 Y Zheng, C Zhang, DR Croucher, MA Soliman, N St-Denis, A Pasculescu, ... Nature 499 (7457), 166-171, 2013 | 312 | 2013 |
| Novel Activating Mutations in the neu Proto-oncogene Involved in Induction of Mammary Tumors PM Siegel, DL Dankort, WR Hardy, WJ Muller Molecular and cellular biology 14 (11), 7068-7077, 1994 | 304 | 1994 |
| ShcA signalling is essential for tumour progression in mouse models of human breast cancer J Ursini‐Siegel, WR Hardy, D Zuo, SHL Lam, V Sanguin‐Gendreau, ... The EMBO journal 27 (6), 910-920, 2008 | 185 | 2008 |
| Strain-Dependent Myeloid Hyperplasia, Growth Deficiency, and Accelerated Cell Cycle in Mice Lacking the Rb-Related p107 Gene JE LeCouter, B Kablar, WR Hardy, C Ying, LA Megeney, LL May, ... Molecular and cellular biology 18 (12), 7455-7465, 1998 | 181 | 1998 |
| ErbB2 is required for muscle spindle and myoblast cell survival ER Andrechek, WR Hardy, AA Girgis-Gabardo, RLS Perry, R Butler, ... Molecular and cellular biology 22 (13), 4714-4722, 2002 | 154 | 2002 |
| Screening for PTB domain binding partners and ligand specificity using proteome-derived NPXY peptide arrays MJ Smith, WR Hardy, JM Murphy, N Jones, T Pawson Molecular and cellular biology 26 (22), 8461-8474, 2006 | 138 | 2006 |
| The catalytic activity of the ErbB-2 receptor tyrosine kinase is essential for embryonic development R Chan, WR Hardy, MA Laing, SE Hardy, WJ Muller Molecular and cellular biology, 2002 | 84 | 2002 |
| Analysis of a Shc family adaptor protein, ShcD/Shc4, that associates with muscle-specific kinase N Jones, WR Hardy, MB Friese, C Jorgensen, MJ Smith, NM Woody, ... Molecular and cellular biology 27 (13), 4759-4773, 2007 | 82 | 2007 |
| Neutralization against Omicron variant in transplant recipients after three doses of mRNA vaccine D Kumar, Q Hu, R Samson, VH Ferreira, VG Hall, M Ierullo, ... American Journal of Transplantation 22 (8), 2089-2093, 2022 | 74 | 2022 |
| Combinatorial ShcA docking interactions support diversity in tissue morphogenesis WR Hardy, L Li, Z Wang, J Sedy, J Fawcett, E Frank, J Kucera, T Pawson Science 317 (5835), 251-256, 2007 | 72 | 2007 |
| UNC-129 regulates the balance between UNC-40 dependent and independent UNC-5 signaling pathways LT MacNeil, WR Hardy, T Pawson, JL Wrana, JG Culotti Nature neuroscience 12 (2), 150-155, 2009 | 64 | 2009 |
| Modification of the Creator recombination system for proteomics applications–improved expression by addition of splice sites K Colwill, CD Wells, K Elder, M Goudreault, K Hersi, S Kulkarni, ... BMC biotechnology 6, 1-15, 2006 | 60 | 2006 |
| Mammary gland neoplasia: insights from transgenic mouse models PM Siegel, WR Hardy, WJ Muller Bioessays 22 (6), 554-563, 2000 | 54 | 2000 |
| Accelerated waning of immunity to SARS-CoV-2 mRNA vaccines in patients with immune-mediated inflammatory diseases RM Dayam, JC Law, RL Goetgebuer, GYC Chao, KT Abe, M Sutton, ... JCI insight 7 (11), 2022 | 41 | 2022 |
| An embryonic stem cell-specific NuRD complex functions through interaction with WDR5 LS Ee, KN McCannell, Y Tang, N Fernandes, WR Hardy, MR Green, ... Stem cell reports 8 (6), 1488-1496, 2017 | 41 | 2017 |
| Neutralizing antibody responses to SARS-CoV-2 variants in vaccinated Ontario long-term care home residents and workers KT Abe, Q Hu, M Mozafarihashjin, R Samson, K Manguiat, A Robinson, ... medRxiv, 2021.08. 06.21261721, 2021 | 36 | 2021 |
| Preclinical evaluation of a SARS-CoV-2 mRNA vaccine PTX-COVID19-B J Liu, P Budylowski, R Samson, BD Griffin, G Babuadze, B Rathod, ... Science Advances 8 (3), eabj9815, 2022 | 34 | 2022 |
| Distinct phosphotyrosine-dependent functions of the ShcA adaptor protein are required for transforming growth factor β (TGFβ)-induced breast cancer cell migration, invasion … JJ Northey, Z Dong, E Ngan, A Kaplan, WR Hardy, T Pawson, PM Siegel Journal of Biological Chemistry 288 (7), 5210-5222, 2013 | 34 | 2013 |
| Receptor tyrosine kinase signaling favors a protumorigenic state in breast cancer cells by inhibiting the adaptive immune response J Ursini-Siegel, S Cory, D Zuo, WR Hardy, E Rexhepaj, S Lam, B Schade, ... Cancer research 70 (20), 7776-7787, 2010 | 33 | 2010 |
