Role and therapeutic targeting of the PI3K/Akt/mTOR signaling pathway in skin cancer: a review of current status and future trends on natural and synthetic agents therapy JC Chamcheu, T Roy, MB Uddin, S Banang-Mbeumi, RCN Chamcheu, ... Cells 8 (8), 803, 2019 | 172 | 2019 |
Fisetin, a 3, 7, 3′, 4′-tetrahydroxyflavone inhibits the PI3K/Akt/mTOR and MAPK pathways and ameliorates psoriasis pathology in 2D and 3D organotypic human inflammatory skin … JC Chamcheu, S Esnault, VM Adhami, AL Noll, S Banang-Mbeumi, T Roy, ... Cells 8 (9), 1089, 2019 | 72 | 2019 |
Synthesis, inverse docking-assisted identification and in vitro biological characterization of Flavonol-based analogs of fisetin as c-Kit, CDK2 and mTOR inhibitors against … T Roy, ST Boateng, S Banang-Mbeumi, PK Singh, P Basnet, ... Bioorganic chemistry 107, 104595, 2021 | 31 | 2021 |
The PI3K-Akt-mTOR and Associated Signaling Pathways as Molecular Drivers of Immune-Mediated Inflammatory Skin Diseases: Update on Therapeutic Strategy Using Natural and … T Roy, ST Boateng, MB Uddin, S Banang-Mbeumi, RK Yadav, CR Bock, ... Cells 12 (12), 1671, 2023 | 28 | 2023 |
Dual targeting of mTOR/IL-17A and autophagy by fisetin alleviates psoriasis-like skin inflammation T Roy, S Banang-Mbeumi, ST Boateng, EM Ruiz, RCN Chamcheu, ... Frontiers in immunology 13, 1075804, 2023 | 14 | 2023 |
Chronic metabolic acidosis elicits hypertension via upregulation of intrarenal angiotensin II and induction of oxidative stress D Aryal, T Roy, JC Chamcheu, KE Jackson Antioxidants 10 (1), 2, 2020 | 12 | 2020 |
Identification of new fisetin analogs as kinase inhibitors: Data on synthesis and anti-skin cancer activities evaluation T Roy, ST Boateng, S Banang-Mbeumi, PK Singh, P Basnet, ... Data in brief 35, 106858, 2021 | 7 | 2021 |
Nutritional and pharmaceutical applications of under-explored knottin peptide-rich phytomedicines FA Attah, BA Lawal, AB Yusuf, OJ Adedeji, JT Folahan, KO Akhigbe, ... Plants 11 (23), 3271, 2022 | 6 | 2022 |
Synthesis, in silico modelling, and in vitro biological evaluation of substituted pyrazole derivatives as potential anti-skin cancer, anti-tyrosinase, and antioxidant … ST Boateng, T Roy, K Torrey, U Owunna, S Banang-Mbeumi, D Basnet, ... Journal of Enzyme Inhibition and Medicinal Chemistry 38 (1), 2205042, 2023 | 5 | 2023 |
Standardized Pomegranate (Pomella®) and Red Maple (Maplifa®) Extracts and Their Phenolics Protect Type I Collagen by the Inhibition of Matrix … H Li, T Roy, ST Boateng, H He, C Liu, W Liu, D Li, P Wu, NP Seeram, ... Molecules 27 (22), 7919, 2022 | 5 | 2022 |
Role and therapeutic targeting of the PI3K/Akt/mTOR signaling pathway in skin cancer: a review of current status and future trends on natural and synthetic agents therapy … JC Chamcheu, T Roy, MB Uddin, S Banang-Mbeumi, RCN Chamcheu, ... | 5 | |
Identification of potential inhibitors of cutaneous melanoma and non-melanoma skin cancer cells through in-vitro and in-silico screening of a small library of phenolic compounds ST Boateng, T Roy, ME Agbo, S Banang-Mbeumi, RCN Chamcheu, ... bioRxiv, 2022.02. 28.482167, 2022 | 2 | 2022 |
LB1121 Prodifferentiative and anti-inflammatory effects of fisetin in 2D and 3D human skin model of psoriasis are associated with inhibition of PI3K/Akt/mTOR and MAPKásignaling J Chamcheu, S Esnault, S Banang-Mbeumi, T Roy, H Mukhtar Journal of Investigative Dermatology 139 (9), B19, 2019 | 2 | 2019 |
591 Dual targeting mTOR and autophagy by fisetin alleviates psoriasis-like responses induced by TNF-α and IL-17A in vitro and imiquimod-induced dermatitis in vivo T Roy, S Banang-Mbeumi, ST Boateng, R Chamcheu, L Kang, S Huang, ... Journal of Investigative Dermatology 142 (8), S101, 2022 | 1 | 2022 |
The Role of the Central mTOR Signaling Pathway in Psoriasis Pathogenesis and Its Therapeutic Targeting with Fisetin T Roy University of Louisiana at Monroe, 2022 | 1 | 2022 |
In Silico Screening for Novel Inhibitors of Invasion Protein Antigen IpaD of Shigella Flexneri—An Agent of Shigellosis J Alam, T Roy Int. J. Comput. Bioinform. Silico Model 3, 497-501, 2015 | 1 | 2015 |
828 Assessment of the role of IGF2BP1 in basal cell carcinoma development F Noubissi, J Herron, C Harris, M Hajahmed, C Yedjou, J Chamcheu, ... Journal of Investigative Dermatology 144 (8), S144, 2024 | | 2024 |
Multifaceted approach toward mapping out the anticancer properties of small molecules via in vitro evaluation on melanoma and nonmelanoma skin cancer cells, and in silico … ST Boateng, T Roy, ME Agbo, MA Mahmud, S Banang‐Mbeumi, ... Chemical Biology & Drug Design 103 (1), e14418, 2024 | | 2024 |
1135 Identification of novel derivatives of fisetin with anti-inflammatory and antioxidant activities in cutaneous keratinocytes and macrophage RK Yadav, T Roy, ST Boateng, M Mahmud, JT Folahan, ... Journal of Investigative Dermatology 143 (5), S194, 2023 | | 2023 |
1110 Bioassay-guided fractions of garcinia kola nuts inhibit cell proliferation via modulation of PI3K/Akt/mTOR pathway in melanoma and non-melanoma skin cancers JT Folahan, ST Boateng, T Roy, RK Yadav, M Mahmud, J Chamcheu Journal of Investigative Dermatology 143 (5), S190, 2023 | | 2023 |