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Tithi Roy
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Role and therapeutic targeting of the PI3K/Akt/mTOR signaling pathway in skin cancer: a review of current status and future trends on natural and synthetic agents therapy
JC Chamcheu, T Roy, MB Uddin, S Banang-Mbeumi, RCN Chamcheu, ...
Cells 8 (8), 803, 2019
1722019
Fisetin, a 3, 7, 3′, 4′-tetrahydroxyflavone inhibits the PI3K/Akt/mTOR and MAPK pathways and ameliorates psoriasis pathology in 2D and 3D organotypic human inflammatory skin …
JC Chamcheu, S Esnault, VM Adhami, AL Noll, S Banang-Mbeumi, T Roy, ...
Cells 8 (9), 1089, 2019
722019
Synthesis, inverse docking-assisted identification and in vitro biological characterization of Flavonol-based analogs of fisetin as c-Kit, CDK2 and mTOR inhibitors against …
T Roy, ST Boateng, S Banang-Mbeumi, PK Singh, P Basnet, ...
Bioorganic chemistry 107, 104595, 2021
312021
The PI3K-Akt-mTOR and Associated Signaling Pathways as Molecular Drivers of Immune-Mediated Inflammatory Skin Diseases: Update on Therapeutic Strategy Using Natural and …
T Roy, ST Boateng, MB Uddin, S Banang-Mbeumi, RK Yadav, CR Bock, ...
Cells 12 (12), 1671, 2023
282023
Dual targeting of mTOR/IL-17A and autophagy by fisetin alleviates psoriasis-like skin inflammation
T Roy, S Banang-Mbeumi, ST Boateng, EM Ruiz, RCN Chamcheu, ...
Frontiers in immunology 13, 1075804, 2023
142023
Chronic metabolic acidosis elicits hypertension via upregulation of intrarenal angiotensin II and induction of oxidative stress
D Aryal, T Roy, JC Chamcheu, KE Jackson
Antioxidants 10 (1), 2, 2020
122020
Identification of new fisetin analogs as kinase inhibitors: Data on synthesis and anti-skin cancer activities evaluation
T Roy, ST Boateng, S Banang-Mbeumi, PK Singh, P Basnet, ...
Data in brief 35, 106858, 2021
72021
Nutritional and pharmaceutical applications of under-explored knottin peptide-rich phytomedicines
FA Attah, BA Lawal, AB Yusuf, OJ Adedeji, JT Folahan, KO Akhigbe, ...
Plants 11 (23), 3271, 2022
62022
Synthesis, in silico modelling, and in vitro biological evaluation of substituted pyrazole derivatives as potential anti-skin cancer, anti-tyrosinase, and antioxidant …
ST Boateng, T Roy, K Torrey, U Owunna, S Banang-Mbeumi, D Basnet, ...
Journal of Enzyme Inhibition and Medicinal Chemistry 38 (1), 2205042, 2023
52023
Standardized Pomegranate (Pomella®) and Red Maple (Maplifa®) Extracts and Their Phenolics Protect Type I Collagen by the Inhibition of Matrix …
H Li, T Roy, ST Boateng, H He, C Liu, W Liu, D Li, P Wu, NP Seeram, ...
Molecules 27 (22), 7919, 2022
52022
Role and therapeutic targeting of the PI3K/Akt/mTOR signaling pathway in skin cancer: a review of current status and future trends on natural and synthetic agents therapy …
JC Chamcheu, T Roy, MB Uddin, S Banang-Mbeumi, RCN Chamcheu, ...
5
Identification of potential inhibitors of cutaneous melanoma and non-melanoma skin cancer cells through in-vitro and in-silico screening of a small library of phenolic compounds
ST Boateng, T Roy, ME Agbo, S Banang-Mbeumi, RCN Chamcheu, ...
bioRxiv, 2022.02. 28.482167, 2022
22022
LB1121 Prodifferentiative and anti-inflammatory effects of fisetin in 2D and 3D human skin model of psoriasis are associated with inhibition of PI3K/Akt/mTOR and MAPKásignaling
J Chamcheu, S Esnault, S Banang-Mbeumi, T Roy, H Mukhtar
Journal of Investigative Dermatology 139 (9), B19, 2019
22019
591 Dual targeting mTOR and autophagy by fisetin alleviates psoriasis-like responses induced by TNF-α and IL-17A in vitro and imiquimod-induced dermatitis in vivo
T Roy, S Banang-Mbeumi, ST Boateng, R Chamcheu, L Kang, S Huang, ...
Journal of Investigative Dermatology 142 (8), S101, 2022
12022
The Role of the Central mTOR Signaling Pathway in Psoriasis Pathogenesis and Its Therapeutic Targeting with Fisetin
T Roy
University of Louisiana at Monroe, 2022
12022
In Silico Screening for Novel Inhibitors of Invasion Protein Antigen IpaD of Shigella Flexneri—An Agent of Shigellosis
J Alam, T Roy
Int. J. Comput. Bioinform. Silico Model 3, 497-501, 2015
12015
828 Assessment of the role of IGF2BP1 in basal cell carcinoma development
F Noubissi, J Herron, C Harris, M Hajahmed, C Yedjou, J Chamcheu, ...
Journal of Investigative Dermatology 144 (8), S144, 2024
2024
Multifaceted approach toward mapping out the anticancer properties of small molecules via in vitro evaluation on melanoma and nonmelanoma skin cancer cells, and in silico …
ST Boateng, T Roy, ME Agbo, MA Mahmud, S Banang‐Mbeumi, ...
Chemical Biology & Drug Design 103 (1), e14418, 2024
2024
1135 Identification of novel derivatives of fisetin with anti-inflammatory and antioxidant activities in cutaneous keratinocytes and macrophage
RK Yadav, T Roy, ST Boateng, M Mahmud, JT Folahan, ...
Journal of Investigative Dermatology 143 (5), S194, 2023
2023
1110 Bioassay-guided fractions of garcinia kola nuts inhibit cell proliferation via modulation of PI3K/Akt/mTOR pathway in melanoma and non-melanoma skin cancers
JT Folahan, ST Boateng, T Roy, RK Yadav, M Mahmud, J Chamcheu
Journal of Investigative Dermatology 143 (5), S190, 2023
2023
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