| Intra-arterial prourokinase for acute ischemic stroke: the PROACT II study: a randomized controlled trial A Furlan, R Higashida, L Wechsler, M Gent, H Rowley, C Kase, M Pessin, ... Jama 282 (21), 2003-2011, 1999 | 4144 | 1999 |
| Stenting versus endarterectomy for treatment of carotid-artery stenosis TG Brott, RW Hobson, G Howard, GS Roubin, WM Clark, W Brooks, ... New England Journal of Medicine 363 (1), 11-23, 2010 | 3554 | 2010 |
| Endovascular therapy after intravenous t-PA versus t-PA alone for stroke JP Broderick, YY Palesch, AM Demchuk, SD Yeatts, P Khatri, MD Hill, ... New England Journal of Medicine 368 (10), 893-903, 2013 | 2329 | 2013 |
| Recombinant tissue-type plasminogen activator (alteplase) for ischemic stroke 3 to 5 hours after symptom onset: the ATLANTIS study: a randomized controlled trial WM Clark, S Wissman, GW Albers, JH Jhamandas, KP Madden, ... Jama 282 (21), 2019-2026, 1999 | 1700 | 1999 |
| Solitaire flow restoration device versus the Merci Retriever in patients with acute ischaemic stroke (SWIFT): a randomised, parallel-group, non-inferiority trial JL Saver, R Jahan, EI Levy, TG Jovin, B Baxter, RG Nogueira, W Clark, ... The Lancet 380 (9849), 1241-1249, 2012 | 1654 | 2012 |
| Pioglitazone after ischemic stroke or transient ischemic attack WN Kernan, CM Viscoli, KL Furie, LH Young, SE Inzucchi, M Gorman, ... New England Journal of Medicine 374 (14), 1321-1331, 2016 | 1161 | 2016 |
| Intravenous tissue-type plasminogen activator for treatment of acute stroke: the Standard Treatment with Alteplase to Reverse Stroke (STARS) study GW Albers, VE Bates, WM Clark, R Bell, P Verro, SA Hamilton Jama 283 (9), 1145-1150, 2000 | 991 | 2000 |
| Combined intravenous and intra-arterial r-TPA versus intra-arterial therapy of acute ischemic stroke: Emergency Management of Stroke (EMS) Bridging Trial CA Lewandowski, M Frankel, TA Tomsick, J Broderick, J Frey, W Clark, ... Stroke 30 (12), 2598-2605, 1999 | 891 | 1999 |
| Long-term results of stenting versus endarterectomy for carotid-artery stenosis TG Brott, G Howard, GS Roubin, JF Meschia, A Mackey, W Brooks, ... New England Journal of Medicine 374 (11), 1021-1031, 2016 | 778 | 2016 |
| The rtPA (Alteplase) 0-to 6-hour acute stroke trial, part A (A0276g) Results of a double-blind, placebo-controlled, multicenter study WM Clark, GW Albers, KP Madden, S Hamilton Stroke 31 (4), 811-816, 2000 | 598 | 2000 |
| Use of anti-ICAM-1 therapy in ischemic stroke: results of the Enlimomab Acute Stroke Trial Enlimomab Acute Stroke Trial Investigators Neurology 57 (8), 1428-1434, 2001 | 544 | 2001 |
| Oral citicoline in acute ischemic stroke: an individual patient data pooling analysis of clinical trials A Dávalos, J Castillo, J Álvarez-Sabín, JJ Secades, J Mercadal, S López, ... Stroke 33 (12), 2850-2857, 2002 | 526 | 2002 |
| A randomized dose-response trial of citicoline in acute ischemic stroke patients WM Clark, SJ Warach, LC Pettigrew, RE Gammans, LA Sabounjian, ... Neurology 49 (3), 671-678, 1997 | 427 | 1997 |
| Safety and efficacy of NA-1 in patients with iatrogenic stroke after endovascular aneurysm repair (ENACT): a phase 2, randomised, double-blind, placebo-controlled trial MD Hill, RH Martin, D Mikulis, JH Wong, FL Silver, G Milot, WM Clark, ... The Lancet Neurology 11 (11), 942-950, 2012 | 419 | 2012 |
| Safety of stenting and endarterectomy by symptomatic status in the Carotid Revascularization Endarterectomy Versus Stenting Trial (CREST) FL Silver, A Mackey, WM Clark, W Brooks, CH Timaran, D Chiu, ... Stroke 42 (3), 675-680, 2011 | 398 | 2011 |
| A randomized efficacy trial of citicoline in patients with acute ischemic stroke WM Clark, BJ Williams, KA Selzer, RM Zweifler, LAA Sabounjian, ... Stroke 30 (12), 2592-2597, 1999 | 384 | 1999 |
| Interleukin‐6 and interleukin‐1 receptor antagonist in acute stroke NB Beamer, BM Coull, WM Clark, JS Hazel, JR Silberger Annals of Neurology: Official Journal of the American Neurological …, 1995 | 384 | 1995 |
| A phase III randomized efficacy trial of 2000 mg citicoline in acute ischemic stroke patients WM Clark, LR Wechsler, LA Sabounjian, UE Schwiderski Neurology 57 (9), 1595-1602, 2001 | 366 | 2001 |
| Imaging features and safety and efficacy of endovascular stroke treatment: a meta-analysis of individual patient-level data L San Román, BK Menon, J Blasco, M Hernández-Pérez, A Dávalos, ... The Lancet Neurology 17 (10), 895-904, 2018 | 354 | 2018 |
| Safety and efficacy of multipotent adult progenitor cells in acute ischaemic stroke (MASTERS): a randomised, double-blind, placebo-controlled, phase 2 trial DC Hess, LR Wechsler, WM Clark, SI Savitz, GA Ford, D Chiu, ... The Lancet Neurology 16 (5), 360-368, 2017 | 340 | 2017 |
