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James W. Checco
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α/β-Peptide foldamers targeting intracellular protein–protein interactions with activity in living cells
JW Checco, EF Lee, M Evangelista, NJ Sleebs, K Rogers, ...
Journal of the American Chemical Society 137 (35), 11365-11375, 2015
1322015
Targeting diverse protein–protein interaction interfaces with α/β-peptides derived from the Z-domain scaffold
JW Checco, DF Kreitler, NC Thomas, DG Belair, NJ Rettko, WL Murphy, ...
Proceedings of the National Academy of Sciences 112 (15), 4552-4557, 2015
1072015
Extending foldamer design beyond α-helix mimicry: α/β-peptide inhibitors of vascular endothelial growth factor signaling
HS Haase, KJ Peterson-Kaufman, SK Lan Levengood, JW Checco, ...
Journal of the American Chemical Society 134 (18), 7652-7655, 2012
1002012
Targeting recognition surfaces on natural proteins with peptidic foldamers
JW Checco, SH Gellman
Current opinion in structural biology 39, 96-105, 2016
872016
Structure‐guided rational design of α/β‐peptide foldamers with high affinity for BCL‐2 family prosurvival proteins
BJ Smith, EF Lee, JW Checco, M Evangelista, SH Gellman, WD Fairlie
ChemBioChem 14 (13), 1564-1572, 2013
742013
Molecular and Physiological Characterization of a Receptor for d-Amino Acid-Containing Neuropeptides
JW Checco, G Zhang, W Yuan, K Yu, S Yin, RH Roberts-Galbraith, ...
ACS chemical biology 13 (5), 1343-1352, 2018
302018
Aplysia allatotropin-related peptide and its newly identified d-amino acid–containing epimer both activate a receptor and a neuronal target
JW Checco, G Zhang, W Yuan, Z Le, J Jing, JV Sweedler
Journal of Biological Chemistry 293 (43), 16862-16873, 2018
292018
Iterative Nonproteinogenic Residue Incorporation Yields α/β‐Peptides with a Helix–Loop–Helix Tertiary Structure and High Affinity for VEGF
JW Checco, SH Gellman
ChemBioChem 18 (3), 291-299, 2017
252017
Differential Post-Translational Amino Acid Isomerization Found among Neuropeptides in Aplysia californica
DH Mast, JW Checco, JV Sweedler
ACS chemical biology 15 (1), 272-281, 2019
222019
Advancing d-amino acid-containing peptide discovery in the metazoan
DH Mast, JW Checco, JV Sweedler
Biochimica et Biophysica Acta (BBA)-Proteins and Proteomics 1869 (1), 140553, 2021
212021
Identifying receptors for neuropeptides and peptide hormones: Challenges and recent progress
MSR Abid, S Mousavi, JW Checco
ACS chemical biology 16 (2), 251-263, 2021
182021
Conformational investigation of the structure–activity relationship of GdFFD and its analogues on an achatin-like neuropeptide receptor of Aplysia californica involved in the …
TD Do, JW Checco, M Tro, JE Shea, MT Bowers, JV Sweedler
Physical Chemistry Chemical Physics 20 (34), 22047-22057, 2018
122018
Non-targeted Identification of d-Amino Acid-Containing Peptides Through Enzymatic Screening, Chiral Amino Acid Analysis, and LC-MS
HC Tai, JW Checco, JV Sweedler
Peptidomics: Methods and Strategies, 107-118, 2018
92018
Mass spectrometry approaches empowering neuropeptide discovery and therapeutics
KDB Anapindi, EV Romanova, JW Checco, JV Sweedler
Pharmacological Reviews 74 (3), 662-679, 2022
82022
Short-term administration of common anesthetics does not dramatically change the endogenous peptide profile in the rat pituitary
S Mousavi, H Qiu, FI Heinis, MSR Abid, MT Andrews, JW Checco
ACS chemical neuroscience 13 (19), 2888-2896, 2022
72022
Peptidomics analysis reveals changes in small urinary peptides in patients with interstitial cystitis/bladder pain syndrome
MSR Abid, H Qiu, BA Tripp, A de Lima Leite, HE Roth, J Adamec, ...
Scientific reports 12 (1), 8289, 2022
72022
Peptidomic analysis reveals seasonal neuropeptide and peptide hormone changes in the hypothalamus and pituitary of a hibernating mammal
S Mousavi, H Qiu, MT Andrews, JW Checco
ACS Chemical Neuroscience 14 (14), 2569-2581, 2023
52023
AI protein structure prediction-based modeling and mutagenesis of a protostome receptor and peptide ligands reveal key residues for their interaction
SQ Guo, YD Li, P Chen, G Zhang, HY Wang, HM Jiang, WJ Liu, JP Xu, ...
Journal of Biological Chemistry 298 (10), 2022
52022
Trimer-to-Monomer Disruption Mechanism for a Potent, Protease-Resistant Antagonist of Tumor Necrosis Factor-α Signaling
J Niu, AJ Cederstrand, GA Eddinger, B Yin, JW Checco, CA Bingman, ...
Journal of the American Chemical Society 144 (22), 9610-9617, 2022
52022
Tumor necrosis factor-α trimer disassembly and inactivation via peptide-small molecule synergy
JW Checco, GA Eddinger, NJ Rettko, AR Chartier, SH Gellman
ACS chemical biology 15 (8), 2116-2124, 2020
52020
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Articles 1–20