| Kinetically inert transition metal complexes that reversibly bind to DNA C Metcalfe, JA Thomas Chemical Society Reviews 32 (4), 215-224, 2003 | 811 | 2003 |
| Neutron cryo-crystallography captures the protonation state of ferryl heme in a peroxidase CM Casadei, A Gumiero, CL Metcalfe, EJ Murphy, J Basran, MG Concilio, ... Science 345 (6193), 193-197, 2014 | 144* | 2014 |
| Nature of the ferryl heme in compounds I and II A Gumiero, CL Metcalfe, AR Pearson, EL Raven, PCE Moody Journal of biological chemistry 286 (2), 1260-1268, 2011 | 119 | 2011 |
| The tuberculosis prodrug isoniazid bound to activating peroxidases C Metcalfe, IK Macdonald, EJ Murphy, KA Brown, EL Raven, PCE Moody Journal of biological chemistry 283 (10), 6193-6200, 2008 | 103 | 2008 |
| Electrochemical and photophysical properties of DNA metallo-intercalators containing the ruthenium (II) tris (1-pyrazolyl) methane unit SP Foxon, C Metcalfe, H Adams, M Webb, JA Thomas Inorganic chemistry 46 (2), 409-416, 2007 | 92 | 2007 |
| Labile disulfide bonds are common at the leucocyte cell surface C Metcalfe, P Cresswell, L Ciaccia, B Thomas, AN Barclay Open biology 1 (3), 110010, 2011 | 90 | 2011 |
| Studies on the interaction of extended terpyridyl and triazine metal complexes with DNA C Metcalfe, C Rajput, JA Thomas Journal of inorganic biochemistry 100 (8), 1314-1319, 2006 | 83 | 2006 |
| An analysis of substrate binding interactions in the heme peroxidase enzymes: a structural perspective A Gumiero, EJ Murphy, CL Metcalfe, PCE Moody, EL Raven Archives of biochemistry and biophysics 500 (1), 13-20, 2010 | 78 | 2010 |
| Structures of CD6 and its ligand CD166 give insight into their interaction PE Chappell, LI Garner, J Yan, C Metcalfe, D Hatherley, S Johnson, ... Structure 23 (8), 1426-1436, 2015 | 77 | 2015 |
| Autocatalytic Formation of Green Heme: Evidence for H2O2-Dependent Formation of a Covalent Methionine−Heme Linkage in Ascorbate Peroxidase CL Metcalfe, M Ott, N Patel, K Singh, SC Mistry, HM Goff, EL Raven Journal of the American Chemical Society 126 (49), 16242-16248, 2004 | 50 | 2004 |
| Interleukin-2 signalling is modulated by a labile disulfide bond in the CD132 chain of its receptor C Metcalfe, P Cresswell, AN Barclay Open biology 2 (1), 110036, 2012 | 49 | 2012 |
| A ruthenium dipyridophenazine complex that binds preferentially to GC sequences C Metcalfe, H Adams, I Haq, JA Thomas Chemical communications, 1152-1153, 2003 | 49 | 2003 |
| A facile route to bimetallic ruthenium dipyridophenazine complexes C Metcalfe, I Haq, JA Thomas Inorganic chemistry 43 (1), 317-323, 2004 | 42 | 2004 |
| Engineering the Substrate Specificity and Reactivity of a Heme Protein: Creation of an Ascorbate Binding Site in Cytochrome c Peroxidase EJ Murphy, CL Metcalfe, J Basran, PCE Moody, EL Raven Biochemistry 47 (52), 13933-13941, 2008 | 40 | 2008 |
| A facile synthetic route to bimetallic Re I complexes containing two dppz DNA intercalating ligands C Metcalfe, M Webb, JA Thomas Chemical communications, 2026-2027, 2002 | 40 | 2002 |
| CD44 binding to hyaluronic acid is redox regulated by a labile disulfide bond in the hyaluronic acid binding site H Kellett-Clarke, M Stegmann, AN Barclay, C Metcalfe PloS one 10 (9), e0138137, 2015 | 37 | 2015 |
| Homodimerization of the lymph vessel endothelial receptor LYVE-1 through a redox-labile disulfide is critical for hyaluronan binding in lymphatic endothelium S Banerji, W Lawrance, C Metcalfe, DC Briggs, A Yamauchi, O Dushek, ... Journal of Biological Chemistry 291 (48), 25004-25018, 2016 | 36 | 2016 |
| Crystal structure of guaiacol and phenol bound to a heme peroxidase EJ Murphy, CL Metcalfe, C Nnamchi, PCE Moody, EL Raven The FEBS Journal 279 (9), 1632-1639, 2012 | 36 | 2012 |
| Proton delivery to ferryl heme in a heme peroxidase: enzymatic use of the Grotthuss mechanism I Efimov, SK Badyal, CL Metcalfe, I Macdonald, A Gumiero, EL Raven, ... Journal of the American Chemical Society 133 (39), 15376-15383, 2011 | 36 | 2011 |
| MG Concilio, SCM Teixeira, TE Schrader, AJ Fielding, A. Ostermann, MP Blakeley, EL Raven and PCE Moody CM Casadei, A Gumiero, CL Metcalfe, EJ Murphy, J Basran Science 345 (6193), 193-197, 2014 | 32 | 2014 |
Jim A ThomasUniversity of SheffieldVerified email at sheffield.ac.uk
