| DNA damage foci at dysfunctional telomeres H Takai, A Smogorzewska, T de Lange Current biology 13 (17), 1549-1556, 2003 | 1675 | 2003 |
| p53-and ATM-dependent apoptosis induced by telomeres lacking TRF2 J Karlseder, D Broccoli, Y Dai, S Hardy, T de Lange Science 283 (5406), 1321-1325, 1999 | 1415 | 1999 |
| Telomeres: protecting chromosomes against genome instability RJ O'sullivan, J Karlseder Nature reviews Molecular cell biology 11 (3), 171-181, 2010 | 1114 | 2010 |
| Mammalian telomeres resemble fragile sites and require TRF1 for efficient replication A Sfeir, ST Kosiyatrakul, D Hockemeyer, SL MacRae, J Karlseder, ... Cell 138 (1), 90-103, 2009 | 1086 | 2009 |
| Senescence induced by altered telomere state, not telomere loss J Karlseder, A Smogorzewska, T de Lange Science 295 (5564), 2446-2449, 2002 | 1009 | 2002 |
| Defective telomere lagging strand synthesis in cells lacking WRN helicase activity L Crabbe, RE Verdun, CI Haggblom, J Karlseder Science 306 (5703), 1951-1953, 2004 | 718 | 2004 |
| Replication and protection of telomeres RE Verdun, J Karlseder Nature 447 (7147), 924-931, 2007 | 594 | 2007 |
| The telomeric protein TRF2 binds the ATM kinase and can inhibit the ATM-dependent DNA damage response J Karlseder, K Hoke, OK Mirzoeva, C Bakkenist, MB Kastan, JHJ Petrini, ... PLoS biology 2 (8), e240, 2004 | 475 | 2004 |
| DNA ligase IV-dependent NHEJ of deprotected mammalian telomeres in G1 and G2 A Smogorzewska, J Karlseder, H Holtgreve-Grez, A Jauch, T de Lange Current Biology 12 (19), 1635-1644, 2002 | 463 | 2002 |
| Interaction of Sp1 with the growth-and cell cycle-regulated transcription factor E2F J Karlseder, H Rotheneder, E Wintersberger Molecular and cellular biology, 1996 | 463 | 1996 |
| Reduced histone biosynthesis and chromatin changes arising from a damage signal at telomeres RJ O'sullivan, S Kubicek, SL Schreiber, J Karlseder Nature structural & molecular biology 17 (10), 1218-1225, 2010 | 425 | 2010 |
| The DNA damage machinery and homologous recombination pathway act consecutively to protect human telomeres RE Verdun, J Karlseder Cell 127 (4), 709-720, 2006 | 404 | 2006 |
| TERRA and hnRNPA1 orchestrate an RPA-to-POT1 switch on telomeric single-stranded DNA RL Flynn, RC Centore, RJ O’Sullivan, R Rai, A Tse, Z Songyang, S Chang, ... Nature 471 (7339), 532-536, 2011 | 396 | 2011 |
| Autophagic cell death restricts chromosomal instability during replicative crisis J Nassour, R Radford, A Correia, JM Fusté, B Schoell, A Jauch, RJ Shaw, ... Nature 565 (7741), 659-663, 2019 | 364 | 2019 |
| Functional human telomeres are recognized as DNA damage in G2 of the cell cycle RE Verdun, L Crabbe, C Haggblom, J Karlseder Molecular cell 20 (4), 551-561, 2005 | 338 | 2005 |
| Telomere dysfunction as a cause of genomic instability in Werner syndrome L Crabbe, A Jauch, CM Naeger, H Holtgreve-Grez, J Karlseder Proceedings of the National Academy of Sciences 104 (7), 2205-2210, 2007 | 273 | 2007 |
| Rapid induction of alternative lengthening of telomeres by depletion of the histone chaperone ASF1 RJ O'sullivan, N Arnoult, DH Lackner, L Oganesian, C Haggblom, ... Nature structural & molecular biology 21 (2), 167-174, 2014 | 260 | 2014 |
| Regulation of DNA repair pathway choice in S and G2 phases by the NHEJ inhibitor CYREN N Arnoult, A Correia, J Ma, A Merlo, S Garcia-Gomez, M Maric, M Tognetti, ... Nature 549 (7673), 548-552, 2017 | 249 | 2017 |
| Targeted deletion reveals an essential function for the telomere length regulator Trf1 J Karlseder, L Kachatrian, H Takai, K Mercer, S Hingorani, T Jacks, ... Molecular and cellular biology, 2003 | 236 | 2003 |
| Complex interactions between the DNA-damage response and mammalian telomeres N Arnoult, J Karlseder Nature structural & molecular biology 22 (11), 859-866, 2015 | 233 | 2015 |
