| BRAF Mutations in Thyroid Tumors Are Restricted to Papillary Carcinomas and Anaplastic or Poorly Differentiated Carcinomas Arising from Papillary Carcinomas MN Nikiforova, ET Kimura, M Gandhi, PW Biddinger, JA Knauf, F Basolo, ... The Journal of Clinical Endocrinology & Metabolism 88 (11), 5399-5404, 2003 | 1289 | 2003 |
| PTC is a novel rearranged form of the ret proto-oncogene and is frequently detected in vivo in human thyroid papillary carcinomas M Grieco, M Santoro, MT Berlingieri, RM Melillo, R Donghi, I Bongarzone, ... Cell 60 (4), 557-563, 1990 | 1142 | 1990 |
| Activation of RET as a Dominant Transforming Gene by Germline Mutations of MEN2A and MEN2B M Santoro, F Carlomagno, A Romano, DP Bottaro, NA Dathan, M Grieco, ... Science 267 (5196), 381-383, 1995 | 1006 | 1995 |
| Cytoplasmic relocalization and inhibition of the cyclin-dependent kinase inhibitor p27Kip1 by PKB/Akt-mediated phosphorylation in breast cancer G Viglietto, ML Motti, P Bruni, RM Melillo, A D'alessio, D Califano, F Vinci, ... Nature medicine 8 (10), 1136-1144, 2002 | 896 | 2002 |
| Roles of HMGA proteins in cancer A Fusco, M Fedele Nature Reviews Cancer 7 (12), 899-910, 2007 | 808 | 2007 |
| ZD6474, an orally available inhibitor of KDR tyrosine kinase activity, efficiently blocks oncogenic RET kinases F Carlomagno, D Vitagliano, T Guida, F Ciardiello, G Tortora, G Vecchio, ... Cancer research 62 (24), 7284-7290, 2002 | 712 | 2002 |
| MicroRNA deregulation in human thyroid papillary carcinomas P Pallante, R Visone, M Ferracin, A Ferraro, MT Berlingieri, G Troncone, ... Endocrine-related cancer 13 (2), 497-508, 2006 | 647 | 2006 |
| Regulation of Thyroid Cell Proliferation by TSH and Other Factors: A Critical Evaluation of in Vitro Models T Kimura, A Van Keymeulen, J Golstein, A Fusco, JE Dumont, PP Roger Endocrine reviews 22 (5), 631-656, 2001 | 626 | 2001 |
| MicroRNAs (miR)-221 and miR-222, both overexpressed in human thyroid papillary carcinomas, regulate p27Kip1 protein levels and cell cycle R Visone, L Russo, P Pallante, I De Martino, A Ferraro, V Leone, ... Endocrine-related cancer 14 (3), 791-798, 2007 | 562 | 2007 |
| Bioactive IL-18 expression is up-regulated in Crohn’s disease G Monteleone, F Trapasso, T Parrello, L Biancone, A Stella, R Iuliano, ... The Journal of Immunology 163 (1), 143-147, 1999 | 525 | 1999 |
| A new oncogene in human thyroid papillary carcinomas and their lymph-nodal metastases A Fusco, M Grieco, M Santoro, MT Berlingieri, S Pilotti, MA Pierotti, ... Nature 328 (6126), 170-172, 1987 | 517 | 1987 |
| Molecular characterization of RET/PTC3; a novel rearranged version of the RETproto-oncogene in a human thyroid papillary carcinoma. M Santoro, NA Dathan, MT Berlingieri, I Bongarzone, C Paulin, M Grieco, ... Oncogene 9 (2), 509-516, 1994 | 478 | 1994 |
| Specific microRNAs are downregulated in human thyroid anaplastic carcinomas R Visone, P Pallante, A Vecchione, R Cirombella, M Ferracin, A Ferraro, ... Oncogene 26 (54), 7590-7595, 2007 | 473 | 2007 |
| Mutation of the PIK3CA Gene in Anaplastic Thyroid Cancer G García-Rostán, AM Costa, I Pereira-Castro, G Salvatore, R Hernandez, ... Cancer research 65 (22), 10199-10207, 2005 | 430 | 2005 |
| The RET/PTC-RAS-BRAF linear signaling cascade mediates the motile and mitogenic phenotype of thyroid cancer cells RM Melillo, MD Castellone, V Guarino, V De Falco, AM Cirafici, ... The Journal of clinical investigation 115 (4), 1068-1081, 2005 | 423 | 2005 |
| Increased BDNF promoter methylation in the Wernicke area of suicide subjects S Keller, M Sarchiapone, F Zarrilli, A Videtič, A Ferraro, V Carli, ... Archives of general psychiatry 67 (3), 258-267, 2010 | 409 | 2010 |
| An increased high-mobility group A2 expression level is associated with malignant phenotype in pancreatic exocrine tissue N Abe, T Watanabe, Y Suzuki, N Matsumoto, T Masaki, T Mori, ... British journal of cancer 89 (11), 2104-2109, 2003 | 396 | 2003 |
| RET/PTC oncogene activation defines a subset of papillary thyroid carcinomas lacking evidence of progression to poorly differentiated or undifferentiated tumor phenotypes. G Tallini, M Santoro, M Helie, F Carlomagno, G Salvatore, G Chiappetta, ... Clinical cancer research: an official journal of the American Association …, 1998 | 391 | 1998 |
| High level expression of the HMGI (Y) gene during embryonic development. G Chiappetta, V Avantaggiato, R Visconti, M Fedele, S Battista, ... Oncogene 13 (11), 2439-2446, 1996 | 384 | 1996 |
| RET/PTC oncogene activation is an early event in thyroid carcinogenesis. G Viglietto, G Chiappetta, FJ Martinez-Tello, FH Fukunaga, G Tallini, ... Oncogene 11 (6), 1207-1210, 1995 | 350 | 1995 |
