| Genetic evidence that β-arrestins are dispensable for the initiation of β2-adrenergic receptor signaling to ERK M O’Hayre, K Eichel, S Avino, X Zhao, DJ Steffen, X Feng, K Kawakami, ... Science signaling 10 (484), eaal3395, 2017 | 209 | 2017 |
| GNASR201C induces pancreatic cystic neoplasms in mice that express activated KRAS by inhibiting YAP1 signaling N Ideno, H Yamaguchi, B Ghosh, S Gupta, T Okumura, DJ Steffen, ... Gastroenterology 155 (5), 1593-1607. e12, 2018 | 68 | 2018 |
| 4E-BP1 is a tumor suppressor protein reactivated by mTOR inhibition in head and neck cancer Z Wang, X Feng, AA Molinolo, D Martin, L Vitale-Cross, N Nohata, M Ando, ... Cancer research 79 (7), 1438-1450, 2019 | 63 | 2019 |
| Expression of an active Gαs mutant in skeletal stem cells is sufficient and necessary for fibrous dysplasia initiation and maintenance X Zhao, P Deng, R Iglesias-Bartolome, P Amornphimoltham, DJ Steffen, ... Proceedings of the National Academy of Sciences 115 (3), E428-E437, 2018 | 62 | 2018 |
| Mass spectrometry-based visualization of molecules associated with human habitats D Petras, LF Nothias, RA Quinn, T Alexandrov, N Bandeira, A Bouslimani, ... Analytical chemistry 88 (22), 10775-10784, 2016 | 51 | 2016 |
| A protein network map of head and neck cancer reveals PIK3CA mutant drug sensitivity DL Swaney, DJ Ramms, Z Wang, J Park, Y Goto, M Soucheray, N Bhola, ... Science 374 (6563), eabf2911, 2021 | 39 | 2021 |
| Interpretation of cancer mutations using a multiscale map of protein systems F Zheng, MR Kelly, DJ Ramms, ML Heintschel, K Tao, B Tutuncuoglu, ... Science 374 (6563), eabf3067, 2021 | 33 | 2021 |
| Gαs–Protein Kinase A (PKA) Pathway Signalopathies: The Emerging Genetic Landscape and Therapeutic Potential of Human Diseases Driven by Aberrant Gαs-PKA Signaling DJ Ramms, F Raimondi, N Arang, FW Herberg, SS Taylor, JS Gutkind Pharmacological Reviews 73 (4), 1326-1368, 2021 | 33 | 2021 |
| Microneedle-mediated intratumoral delivery of anti-CTLA-4 promotes cDC1-dependent eradication of oral squamous cell carcinoma with limited irAEs M Gilardi, R Saddawi-Konefka, VH Wu, MA Lopez-Ramirez, Z Wang, ... Molecular Cancer Therapeutics, 2022 | 23 | 2022 |
| Evaluating the Anticancer Properties of Liposomal Copper in a Nude Xenograft Mouse Model of Human Prostate Cancer: Formulation, In Vitro, In Vivo, Histology … Y Wang, S Zeng, TM Lin, L Krugner-Higby, D Lyman, D Steffen, MP Xiong Pharmaceutical research 31 (11), 3106-3119, 2014 | 18 | 2014 |
| A reversible SRC-relayed COX2 inflammatory program drives resistance to BRAF and EGFR inhibition in BRAFV600E colorectal tumors A Ruiz-Saenz, CE Atreya, C Wang, B Pan, CA Dreyer, D Brunen, ... Nature Cancer 4 (2), 240-256, 2023 | 16 | 2023 |
| Iron complexation to histone deacetylase inhibitors SAHA and LAQ824 in PEGylated liposomes can considerably improve pharmacokinetics in rats Y Wang, S Tu, D Steffen, M Xiong Journal of pharmacy & pharmaceutical sciences 17 (4), 583-602, 2014 | 12 | 2014 |
| GNAS-PKA Oncosignaling Network in Colorectal Cancer DJ Steffen, P Amornphimoltham, JLC Valera, S Taylor, T Hunter, ... The FASEB Journal 32 (1_supplement), 695.9-695.9, 2018 | 3 | 2018 |
| Gαs (GNAS) suppression of the p53 genomic‐stability checkpoint unleashes RAS‐driven oncogenesis DJ Steffen, H Tiriac, JLC Valera, P Amornphimoltham, W Kim, S Taylor, ... The FASEB Journal 34 (S1), 1-1, 2020 | 1 | 2020 |
| Gαs is dispensable for β-arrestin coupling but dictates GRK selectivity and is predominant for gene expression regulation by β2-adrenergic receptor V Burghi, JS Paradis, A Officer, SR Adame-Garcia, X Wu, ESF Matthees, ... Journal of Biological Chemistry 299 (11), 2023 | | 2023 |
| Abstract B023: A reversible SRC-relayed COX2-inflammatory program drives therapeutic resistance in BRAF (V600E) colorectal tumors CE Atreya, A Ruiz-Saenz, C Wang, B Pan, CA Dreyer, D Brunen, ... Molecular Cancer Therapeutics 18 (12_Supplement), B023-B023, 2019 | | 2019 |
| Mass Spectrometry-Based 3D Cartography Displays the Chemistry Associated with Modern Human Habitats D Petras, LF Nothias, RA Quinn, T Alexandrov, N Bandeira, A Bouslimani, ... Analytical chemistry 88 (22), 10775, 2016 | | 2016 |
Zhiyong WangUC San DiegoVerified email at ucsd.edu
Zhiyong WangUC San DiegoVerified email at ucsd.edu