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Kevin Bi
Kevin Bi
Computational Biologist, Dana Farber Cancer Institute
Verified email at broadinstitute.org
Title
Cited by
Cited by
Year
Subsets of exhausted CD8+ T cells differentially mediate tumor control and respond to checkpoint blockade
BC Miller, DR Sen, R Al Abosy, K Bi, YV Virkud, MW LaFleur, KB Yates, ...
Nature immunology 20 (3), 326-336, 2019
13682019
Normalizing the environment recapitulates adult human immune traits in laboratory mice
LK Beura, SE Hamilton, K Bi, JM Schenkel, OA Odumade, KA Casey, ...
Nature 532 (7600), 512-516, 2016
9992016
In vivo CRISPR screening identifies Ptpn2 as a cancer immunotherapy target
RT Manguso, HW Pope, MD Zimmer, FD Brown, KB Yates, BC Miller, ...
Nature 547 (7664), 413-418, 2017
9812017
Loss of ADAR1 in tumours overcomes resistance to immune checkpoint blockade
JJ Ishizuka, RT Manguso, CK Cheruiyot, K Bi, A Panda, A Iracheta-Vellve, ...
Nature 565 (7737), 43-48, 2019
5012019
Tumor and immune reprogramming during immunotherapy in advanced renal cell carcinoma
K Bi, MX He, Z Bakouny, A Kanodia, S Napolitano, J Wu, G Grimaldi, ...
Cancer cell 39 (5), 649-661. e5, 2021
3152021
Sequential infection with common pathogens promotes human-like immune gene expression and altered vaccine response
TA Reese, K Bi, A Kambal, A Filali-Mouhim, LK Beura, MC Bürger, ...
Cell host & microbe 19 (5), 713-719, 2016
2252016
Mixed signature of activation and dysfunction allows human decidual CD8+ T cells to provide both tolerance and immunity
A van der Zwan, K Bi, ER Norwitz, ÂC Crespo, FHJ Claas, JL Strominger, ...
Proceedings of the National Academy of Sciences 115 (2), 385-390, 2018
1332018
Transcriptional mediators of treatment resistance in lethal prostate cancer
MX He, MS Cuoco, J Crowdis, A Bosma-Moody, Z Zhang, K Bi, A Kanodia, ...
Nature medicine 27 (3), 426-433, 2021
1122021
Integrative molecular characterization of sarcomatoid and rhabdoid renal cell carcinoma
Z Bakouny, DA Braun, SA Shukla, W Pan, X Gao, Y Hou, A Flaifel, S Tang, ...
Nature communications 12 (1), 808, 2021
982021
Targeted reconstruction of T cell receptor sequence from single cell RNA-seq links CDR3 length to T cell differentiation state
S Afik, KB Yates, K Bi, S Darko, J Godec, U Gerdemann, L Swadling, ...
Nucleic acids research 45 (16), e148-e148, 2017
792017
Evolution of delayed resistance to immunotherapy in a melanoma responder
D Liu, JR Lin, EJ Robitschek, GG Kasumova, A Heyde, A Shi, A Kraya, ...
Nature medicine 27 (6), 985-992, 2021
772021
The T cell antigen receptor α transmembrane domain coordinates triggering through regulation of bilayer immersion and CD3 subunit associations
KN Brazin, RJ Mallis, A Boeszoermenyi, Y Feng, A Yoshizawa, PA Reche, ...
Immunity 49 (5), 829-841. e6, 2018
642018
Fibroblastic reticular cells enhance T cell metabolism and survival via epigenetic remodeling
FD Brown, DR Sen, MW LaFleur, J Godec, V Lukacs-Kornek, ...
Nature immunology 20 (12), 1668-1680, 2019
612019
Comparative transcriptome analysis reveals distinct genetic modules associated with Helios expression in intratumoral regulatory T cells
K Yates, K Bi, WN Haining, H Cantor, HJ Kim
Proceedings of the National Academy of Sciences 115 (9), 2162-2167, 2018
462018
TCR‐pMHC encounter differentially regulates transcriptomes of tissue‐resident CD8 T cells
A Yoshizawa, K Bi, DB Keskin, G Zhang, B Reinhold, EL Reinherz
European journal of immunology 48 (1), 128-150, 2018
352018
PI3K activation allows immune evasion by promoting an inhibitory myeloid tumor microenvironment
NB Collins, R Al Abosy, BC Miller, K Bi, Q Zhao, M Quigley, JJ Ishizuka, ...
Journal for ImmunoTherapy of Cancer 10 (3), 2022
262022
Recapitulating adult human immune traits in laboratory mice by normalizing environment
LK Beura, SE Hamilton, K Bi, JM Schenkel, OA Odumade, KA Casey, ...
Nature 532 (7600), 512, 2016
142016
PI3K activated tumors evade tumor immunity by promoting an inhibitory myeloid microenvironment
NB Collins, RA Abosy, B Miller, K Bi, R Manguso, K Yates, WN Haining
The Journal of Immunology 202 (1_Supplement), 58.17-58.17, 2019
62019
Targeted reconstruction of T cell receptor sequence from single cell RNA-sequencing links CDR3 length to T cell differentiation state
S Afik, KB Yates, K Bi, S Darko, J Godec, U Gerdemann, L Swadling, ...
bioRxiv, 072744, 2016
62016
Integrative Molecular Characterization of Sarcomatoid and Rhabdoid Renal Cell Carcinoma Reveals Determinants of Poor Prognosis and Response to Immune Checkpoint Inhibitors
Z Bakouny, DA Braun, SA Shukla, W Pan, X Gao, Y Hou, A Flaifel, S Tang, ...
bioRxiv, 2020.05. 28.121806, 2020
42020
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