Subsets of exhausted CD8+ T cells differentially mediate tumor control and respond to checkpoint blockade BC Miller, DR Sen, R Al Abosy, K Bi, YV Virkud, MW LaFleur, KB Yates, ... Nature immunology 20 (3), 326-336, 2019 | 1368 | 2019 |
Normalizing the environment recapitulates adult human immune traits in laboratory mice LK Beura, SE Hamilton, K Bi, JM Schenkel, OA Odumade, KA Casey, ... Nature 532 (7600), 512-516, 2016 | 999 | 2016 |
In vivo CRISPR screening identifies Ptpn2 as a cancer immunotherapy target RT Manguso, HW Pope, MD Zimmer, FD Brown, KB Yates, BC Miller, ... Nature 547 (7664), 413-418, 2017 | 981 | 2017 |
Loss of ADAR1 in tumours overcomes resistance to immune checkpoint blockade JJ Ishizuka, RT Manguso, CK Cheruiyot, K Bi, A Panda, A Iracheta-Vellve, ... Nature 565 (7737), 43-48, 2019 | 501 | 2019 |
Tumor and immune reprogramming during immunotherapy in advanced renal cell carcinoma K Bi, MX He, Z Bakouny, A Kanodia, S Napolitano, J Wu, G Grimaldi, ... Cancer cell 39 (5), 649-661. e5, 2021 | 315 | 2021 |
Sequential infection with common pathogens promotes human-like immune gene expression and altered vaccine response TA Reese, K Bi, A Kambal, A Filali-Mouhim, LK Beura, MC Bürger, ... Cell host & microbe 19 (5), 713-719, 2016 | 225 | 2016 |
Mixed signature of activation and dysfunction allows human decidual CD8+ T cells to provide both tolerance and immunity A van der Zwan, K Bi, ER Norwitz, ÂC Crespo, FHJ Claas, JL Strominger, ... Proceedings of the National Academy of Sciences 115 (2), 385-390, 2018 | 133 | 2018 |
Transcriptional mediators of treatment resistance in lethal prostate cancer MX He, MS Cuoco, J Crowdis, A Bosma-Moody, Z Zhang, K Bi, A Kanodia, ... Nature medicine 27 (3), 426-433, 2021 | 112 | 2021 |
Integrative molecular characterization of sarcomatoid and rhabdoid renal cell carcinoma Z Bakouny, DA Braun, SA Shukla, W Pan, X Gao, Y Hou, A Flaifel, S Tang, ... Nature communications 12 (1), 808, 2021 | 98 | 2021 |
Targeted reconstruction of T cell receptor sequence from single cell RNA-seq links CDR3 length to T cell differentiation state S Afik, KB Yates, K Bi, S Darko, J Godec, U Gerdemann, L Swadling, ... Nucleic acids research 45 (16), e148-e148, 2017 | 79 | 2017 |
Evolution of delayed resistance to immunotherapy in a melanoma responder D Liu, JR Lin, EJ Robitschek, GG Kasumova, A Heyde, A Shi, A Kraya, ... Nature medicine 27 (6), 985-992, 2021 | 77 | 2021 |
The T cell antigen receptor α transmembrane domain coordinates triggering through regulation of bilayer immersion and CD3 subunit associations KN Brazin, RJ Mallis, A Boeszoermenyi, Y Feng, A Yoshizawa, PA Reche, ... Immunity 49 (5), 829-841. e6, 2018 | 64 | 2018 |
Fibroblastic reticular cells enhance T cell metabolism and survival via epigenetic remodeling FD Brown, DR Sen, MW LaFleur, J Godec, V Lukacs-Kornek, ... Nature immunology 20 (12), 1668-1680, 2019 | 61 | 2019 |
Comparative transcriptome analysis reveals distinct genetic modules associated with Helios expression in intratumoral regulatory T cells K Yates, K Bi, WN Haining, H Cantor, HJ Kim Proceedings of the National Academy of Sciences 115 (9), 2162-2167, 2018 | 46 | 2018 |
TCR‐pMHC encounter differentially regulates transcriptomes of tissue‐resident CD8 T cells A Yoshizawa, K Bi, DB Keskin, G Zhang, B Reinhold, EL Reinherz European journal of immunology 48 (1), 128-150, 2018 | 35 | 2018 |
PI3K activation allows immune evasion by promoting an inhibitory myeloid tumor microenvironment NB Collins, R Al Abosy, BC Miller, K Bi, Q Zhao, M Quigley, JJ Ishizuka, ... Journal for ImmunoTherapy of Cancer 10 (3), 2022 | 26 | 2022 |
Recapitulating adult human immune traits in laboratory mice by normalizing environment LK Beura, SE Hamilton, K Bi, JM Schenkel, OA Odumade, KA Casey, ... Nature 532 (7600), 512, 2016 | 14 | 2016 |
PI3K activated tumors evade tumor immunity by promoting an inhibitory myeloid microenvironment NB Collins, RA Abosy, B Miller, K Bi, R Manguso, K Yates, WN Haining The Journal of Immunology 202 (1_Supplement), 58.17-58.17, 2019 | 6 | 2019 |
Targeted reconstruction of T cell receptor sequence from single cell RNA-sequencing links CDR3 length to T cell differentiation state S Afik, KB Yates, K Bi, S Darko, J Godec, U Gerdemann, L Swadling, ... bioRxiv, 072744, 2016 | 6 | 2016 |
Integrative Molecular Characterization of Sarcomatoid and Rhabdoid Renal Cell Carcinoma Reveals Determinants of Poor Prognosis and Response to Immune Checkpoint Inhibitors Z Bakouny, DA Braun, SA Shukla, W Pan, X Gao, Y Hou, A Flaifel, S Tang, ... bioRxiv, 2020.05. 28.121806, 2020 | 4 | 2020 |