| Small-molecule targeting of brachyury transcription factor addiction in chordoma T Sharifnia, MJ Wawer, T Chen, QY Huang, BA Weir, A Sizemore, ... Nature medicine 25 (2), 292-300, 2019 | 141 | 2019 |
| IRF2 is a master regulator of human keratinocyte stem cell fate N Mercado, G Schutzius, C Kolter, D Estoppey, S Bergling, G Roma, ... Nature communications 10 (1), 4676, 2019 | 29 | 2019 |
| Targeted brachyury degradation disrupts a highly specific autoregulatory program controlling chordoma cell identity HE Sheppard, A Dall’Agnese, WD Park, MH Shamim, J Dubrulle, ... Cell Reports Medicine 2 (1), 100188, 2021 | 24 | 2021 |
| Computational drug repositioning identifies potentially active therapies for chordoma JI Traylor, HE Sheppard, V Ravikumar, J Breshears, SM Raza, CY Lin, ... Neurosurgery 88 (2), 428-436, 2021 | 8 | 2021 |
| Democratizing clinical-genomic data: How federated platforms can promote benefits sharing in genomics M Alvarellos, HE Sheppard, I Knarston, C Davison, N Raine, T Seeger, ... Frontiers in Genetics 13, 1045450, 2023 | 7 | 2023 |
| Nuclear relocalization of mutant NPM1 induces downregulation of Hox/Meis1, terminal differentiation, and cell cycle arrest M Gundry, L Brunetti, H Sheppard, A Guzman, M Goodell Experimental Hematology 53, S45, 2017 | 1 | 2017 |
| Structures of the human transcription factor brachyury offer insights into DNA recognition, and identify small molecule binders for the development of degraders for cancer therapy JA Newman, AE Gavard, N Imprachim, H Aitkenhead, HE Sheppard, ... bioRxiv, 2024.06. 06.597736, 2024 | | 2024 |
| Could federated data analysis be the catalyst accelerating the introduction of newborn genome screening for the detection of genetic disease? P Tsipouras, M Chatzou Dunford, H Sheppard, H Gaimster, T Zaoutis Rare Disease and Orphan Drugs Journal 2, 17, 2023 | | 2023 |
| A characterisation of direct and indirect transcription factor inhibition to target brachyury in chordoma HE Sheppard, A Dall’Agnese, WD Park, MS Shamim, J Dubrulle, ... Cancer Research 82 (12_Supplement), 6355-6355, 2022 | | 2022 |
| Abstract LB216: Targeted brachyury degradation disrupts a highly specific autoregulatory program controlling chordoma cell identity HE Sheppard, A Dall'Agnese, WD Park, H Shamim, J Dubrulle, ... Cancer Research 81 (13_Supplement), LB216-LB216, 2021 | | 2021 |
| One year of ABHD2–Where are we now? A Ramsey, CUNCC Hill, C Arrowsmith, CMD Oxford, M Taylor, NG EBI, ... | | |
| A systematic review of drug-like ligands bound to helicases in the PDB A Ramsey, CUNCC Hill, C Arrowsmith, CMD Oxford, M Taylor, NG EBI, ... | | |
| A promising target for non-hormonal contraception–The α/β Hydrolase Domain 2 A Ramsey, CUNCC Hill, C Arrowsmith, CMD Oxford, M Taylor, NG EBI, ... | | |
| An Introduction to developing assays for HDACs A Ramsey, CUNCC Hill, C Arrowsmith, CMD Oxford, M Taylor, NG EBI, ... | | |
| Structure-Based PROTAC Design: Project Overview A Ramsey, CUNCC Hill, C Arrowsmith, CMD Oxford, M Taylor, NG EBI, ... | | |
| Interrogating PR/SET domains for the ability to bind SAH A Ramsey, CUNCC Hill, C Arrowsmith, CMD Oxford, M Taylor, NG EBI, ... | | |
| Plasmodium falciparum asymptomatic infections: in search of the elephant in the room A Ramsey, CUNCC Hill, C Arrowsmith, CMD Oxford, M Taylor, NG EBI, ... | | |
| The next target: SARS-CoV-2 Macrodomain and Its Druggability–Post 13 A Ramsey, CUNCC Hill, C Arrowsmith, CMD Oxford, M Taylor, NG EBI, ... | | |
| Mapping the genetic variations of SARS-CoV-2 onto its proteins’ crystal structures–Post A Ramsey, CUNCC Hill, C Arrowsmith, CMD Oxford, M Taylor, NG EBI, ... | | |
| Mur ligases as targets for new antibiotics A Ramsey, CUNCC Hill, C Arrowsmith, CMD Oxford, M Taylor, NG EBI, ... | | |
