Alzheimer’s disease brain-derived extracellular vesicles spread tau pathology in interneurons Z Ruan, D Pathak, S Venkatesan Kalavai, A Yoshii-Kitahara, S Muraoka, ... Brain 144 (1), 288-309, 2021 | 165 | 2021 |
Proteomic and biological profiling of extracellular vesicles from Alzheimer's disease human brain tissues S Muraoka, AM DeLeo, MK Sethi, K Yukawa‐Takamatsu, Z Yang, J Ko, ... Alzheimer's & Dementia 16 (6), 896-907, 2020 | 117 | 2020 |
The first potent subtype‐selective retinoid X receptor (RXR) agonist possessing a 3‐isopropoxy‐4‐isopropylphenylamino moiety, NEt‐3IP (RXRα/β‐dual agonist) K Takamatsu, A Takano, N Yakushiji, K Morohashi, K Morishita, ... ChemMedChem: Chemistry Enabling Drug Discovery 3 (5), 780-787, 2008 | 58 | 2008 |
Analgesic agents without gastric damage: Design and synthesis of structurally simple benzenesulfonanilide-type cyclooxygenase-1-selective inhibitors X Zheng, H Oda, K Takamatsu, Y Sugimoto, A Tai, E Akaho, HI Ali, ... Bioorganic & Medicinal Chemistry 15 (2), 1014-1021, 2007 | 47 | 2007 |
Replacing alkyl sulfonamide with aromatic sulfonamide in sulfonamide-type RXR agonists favors switch towards antagonist activity K Morishita, N Yakushiji, F Ohsawa, K Takamatsu, N Matsuura, ... Bioorganic & medicinal chemistry letters 19 (3), 1001-1003, 2009 | 25 | 2009 |
Reduction of lipophilicity at the lipophilic domain of RXR agonists enables production of subtype preference: RXRα‐preferential agonist possessing a sulfonamide moiety K Takamatsu, A Takano, N Yakushiji, K Morishita, N Matsuura, ... ChemMedChem: Chemistry Enabling Drug Discovery 3 (3), 454-460, 2008 | 25 | 2008 |
Proteomic Profiling of Extracellular Vesicles Separated from Plasma of Former National Football League Players at Risk for Chronic Traumatic Encephalopathy S Muraoka, AM DeLeo, Z Yang, H Tatebe, K Yukawa-Takamatsu, S Ikezu, ... Aging and disease, 10-100, 2020 | 15 | 2020 |
Rexinoid compound having alkoxy group H Kakuta, K Sasaki, K Takamatsu, A Takano, N Yakushiji, K Morohashi, ... US Patent 8,389,538, 2013 | 11 | 2013 |
Convenient retinoid X receptor binding assay based on fluorescence change of the antagonist NEt-C343 K Yukawa-Takamatsu, Y Wang, M Watanabe, Y Takamura, M Fujihara, ... Journal of medicinal chemistry 64 (1), 861-870, 2020 | 7 | 2020 |
Functional genome-wide short hairpin RNA library screening identifies key molecules for extracellular vesicle secretion from microglia Z Ruan, K Takamatsu-Yukawa, Y Wang, ML Ushman, AT Labadorf, ... Cell reports 39 (6), 2022 | 4 | 2022 |
Enrichment of Phosphorylated Tau (Thr181) and Functionally Interacting Molecules in Chronic Traumatic Encephalopathy Brain-derived Extracellular Vesicles S Muraoka, W Lin, K Takamatsu-Yukawa, J Hu, S Ikezu, MA DeTure, ... Aging and disease, 0, 2020 | 4 | 2020 |
GPR52 accelerates fatty acid biosynthesis in a ligand-dependent manner in hepatocytes and in response to excessive fat intake in mice M Wada, K Yukawa, H Ogasawara, K Suzawa, T Maekawa, Y Yamamoto, ... Iscience 24 (4), 2021 | 2 | 2021 |
Proteomic Profiling and Biological Characterization of Extracellular Vesicles Isolated from Human Alzheimer’s Disease Brain Tissues S Muraoka, AM DeLeo, MK Sethi, K Yukawa-Takamatsu, Z Yang, J Ko, ... bioRxiv, 733477, 2019 | 2 | 2019 |
Antisense oligonucleotide-based targeting of Tau-tubulin kinase 1 prevents hippocampal accumulation of phosphorylated tau in PS19 tauopathy mice K Yukawa, S Yamamoto-Mcguire, L Cafaro, C Hong, F Kamme, T Ikezu, ... Acta Neuropathologica Communications 11 (1), 166, 2023 | 1 | 2023 |
Elucidating the pathogenic mechanisms of AD brain-derived tau-containing extracellular vesicles: Highly transmissible and preferential propagation to GABAergic neurons Z Ruan, D Pathak, SV Kalavai, A Yoshii-Kitahara, S Muraoka, ... BioRxiv, 2020.03. 15.992719, 2020 | 1 | 2020 |
Alzheimer's disease brain-derived tau-containing extracellular vesicles: Pathobiology and GABAergic neuronal transmission Z Ruan, D Pathak, SV Kalavai, A Yoshii-Kitahara, S Muraoka, ... bioRxiv, 2020 | 1 | 2020 |
Antisense-oliognucleotides based targeting of Tau-tubulin kinase 1 reduces phosphorylated tau level in tauopathy mouse model S Ikezu, K Yukawa, S Yamamoto-Mcguire, L Cafaro, C Hong, F Kamme, ... Alzheimer's Association International Conference, 2023 | | 2023 |
" Alzheimer’s disease brain-derived extracellular vesicles spread tau pathology in interneurons": Erratum. Z Ruan, D Pathak, S Venkatesan Kalavai, A Yoshii-Kitahara, S Muraoka, ... Oxford University Press, 2021 | | 2021 |
Erratum to: Alzheimer’s disease brain-derived extracellular vesicles spread tau pathology in interneurons Z Ruan, D Pathak, SV Kalavai, A Yoshii-Kitahara, S Muraoka, N Bhatt, ... Brain 144 (1), e42, 2021 | | 2021 |
Evaluation of extracellular vesicles isolated from the cerebrospinal fluid and plasma from former National Football League players at risk for chronic traumatic encephalopathy … S Muraoka, MP Jedrychowski, Z Yang, H Tatebe, AM DeLeo, K Yukawa, ... Alzheimer's & Dementia 16, e042233, 2020 | | 2020 |