| Monoculture-derived T lymphocytes specific for multiple viruses expand and produce clinically relevant effects in immunocompromised individuals AM Leen, GD Myers, U Sili, MH Huls, H Weiss, KS Leung, G Carrum, ... Nature medicine 12 (10), 1160-1166, 2006 | 643 | 2006 |
| Multicenter study of banked third-party virus-specific T cells to treat severe viral infections after hematopoietic stem cell transplantation AM Leen, CM Bollard, AM Mendizabal, EJ Shpall, P Szabolcs, JH Antin, ... Blood, The Journal of the American Society of Hematology 121 (26), 5113-5123, 2013 | 614 | 2013 |
| Off-the-shelf virus-specific T cells to treat BK virus, human herpesvirus 6, cytomegalovirus, Epstein-Barr virus, and adenovirus infections after allogeneic hematopoietic stem … I Tzannou, A Papadopoulou, S Naik, K Leung, CA Martinez, CA Ramos, ... Journal of Clinical Oncology 35 (31), 3547-3557, 2017 | 468 | 2017 |
| Activity of broad-spectrum T cells as treatment for AdV, EBV, CMV, BKV, and HHV6 infections after HSCT A Papadopoulou, U Gerdemann, UL Katari, I Tzannou, H Liu, C Martinez, ... Science translational medicine 6 (242), 242ra83-242ra83, 2014 | 438 | 2014 |
| Cytotoxic T lymphocyte therapy with donor T cells prevents and treats adenovirus and Epstein-Barr virus infections after haploidentical and matched unrelated stem cell … AM Leen, A Christin, GD Myers, H Liu, CR Cruz, PJ Hanley, ... Blood, The Journal of the American Society of Hematology 114 (19), 4283-4292, 2009 | 377 | 2009 |
| Complete responses of relapsed lymphoma following genetic modification of tumor-antigen presenting cells and T-lymphocyte transfer CM Bollard, S Gottschalk, AM Leen, H Weiss, KC Straathof, G Carrum, ... Blood, The Journal of the American Society of Hematology 110 (8), 2838-2845, 2007 | 347 | 2007 |
| Improving T cell therapy for cancer AM Leen, CM Rooney, AE Foster Annu. Rev. Immunol. 25 (1), 243-265, 2007 | 316 | 2007 |
| Functionally active virus-specific T cells that target CMV, adenovirus, and EBV can be expanded from naive T-cell populations in cord blood and will target a range of viral … PJ Hanley, CRY Cruz, B Savoldo, AM Leen, M Stanojevic, M Khalil, ... Blood, The Journal of the American Society of Hematology 114 (9), 1958-1967, 2009 | 298 | 2009 |
| Differential Immunogenicity of Epstein-Barr Virus Latent-Cycle Proteins for Human CD4+ T-Helper 1 Responses ANN Leen, P Meij, I Redchenko, J Middeldorp, E Bloemena, A Rickinson, ... Journal of virology 75 (18), 8649-8659, 2001 | 297 | 2001 |
| Improving chimeric antigen receptor-modified T cell function by reversing the immunosuppressive tumor microenvironment of pancreatic cancer S Mohammed, S Sukumaran, P Bajgain, N Watanabe, HE Heslop, ... Molecular therapy 25 (1), 249-258, 2017 | 294 | 2017 |
| Rapidly generated multivirus-specific cytotoxic T lymphocytes for the prophylaxis and treatment of viral infections U Gerdemann, JM Keirnan, UL Katari, R Yanagisawa, AS Christin, ... Molecular therapy 20 (8), 1622-1632, 2012 | 277 | 2012 |
| How I treat adenovirus in hematopoietic stem cell transplant recipients CA Lindemans, AM Leen, JJ Boelens Blood, The Journal of the American Society of Hematology 116 (25), 5476-5485, 2010 | 265 | 2010 |
| Safety and clinical efficacy of rapidly-generated trivirus-directed T cells as treatment for adenovirus, EBV, and CMV infections after allogeneic hematopoietic stem cell transplant U Gerdemann, UL Katari, A Papadopoulou, JM Keirnan, JA Craddock, ... Molecular Therapy 21 (11), 2113-2121, 2013 | 263 | 2013 |
| Allogeneic virus-specific T cells with HLA alloreactivity do not produce GVHD in human subjects JJ Melenhorst, AM Leen, CM Bollard, MF Quigley, DA Price, CM Rooney, ... Blood, The Journal of the American Society of Hematology 116 (22), 4700-4702, 2010 | 230 | 2010 |
| Fine-tuning the CAR spacer improves T-cell potency N Watanabe, P Bajgain, S Sukumaran, S Ansari, HE Heslop, CM Rooney, ... Oncoimmunology 5 (12), e1253656, 2016 | 217 | 2016 |
| Accelerated production of antigen-specific T cells for preclinical and clinical applications using gas-permeable rapid expansion cultureware (G-Rex) JF Vera, LJ Brenner, U Gerdemann, MC Ngo, U Sili, H Liu, J Wilson, ... Journal of Immunotherapy 33 (3), 305-315, 2010 | 197 | 2010 |
| Optimizing the production of suspension cells using the G-Rex “M” series P Bajgain, R Mucharla, J Wilson, D Welch, U Anurathapan, B Liang, X Lu, ... Molecular Therapy Methods & Clinical Development 1, 2014 | 189 | 2014 |
| Long-term outcome after haploidentical stem cell transplant and infusion of T cells expressing the inducible caspase 9 safety transgene X Zhou, A Di Stasi, SK Tey, RA Krance, C Martinez, KS Leung, AG Durett, ... Blood, The Journal of the American Society of Hematology 123 (25), 3895-3905, 2014 | 188 | 2014 |
| CD4+ T-Cell Responses to Epstein-Barr Virus (EBV) Latent-Cycle Antigens and the Recognition of EBV-Transformed Lymphoblastoid Cell Lines HM Long, TA Haigh, NH Gudgeon, AM Leen, CW Tsang, J Brooks, ... Journal of virology 79 (8), 4896-4907, 2005 | 182 | 2005 |
| Reversal of tumor immune inhibition using a chimeric cytokine receptor AM Leen, S Sukumaran, N Watanabe, S Mohammed, J Keirnan, ... Molecular Therapy 22 (6), 1211-1220, 2014 | 180 | 2014 |
