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Madelé van Dyk
Madelé van Dyk
Verified email at flinders.edu.au
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Cited by
Cited by
Year
Therapeutic drug monitoring of oral targeted antineoplastic drugs
A Mueller-Schoell, SL Groenland, O Scherf-Clavel, M van Dyk, ...
European journal of clinical pharmacology 77, 441-464, 2021
1622021
Plasma extracellular nanovesicle (exosome)‐derived biomarkers for drug metabolism pathways: a novel approach to characterize variability in drug exposure
A Rowland, W Ruanglertboon, M Van Dyk, D Wijayakumara, LS Wood, ...
British journal of clinical pharmacology 85 (1), 216-226, 2019
762019
Kinase inhibitor pharmacokinetics: comprehensive summary and roadmap for addressing inter-individual variability in exposure
A Rowland, M Van Dyk, AA Mangoni, JO Miners, RA McKinnon, ...
Expert Opinion on Drug Metabolism & Toxicology 13 (1), 31-49, 2017
632017
Perspectives on model‐informed precision dosing in the digital health era: challenges, opportunities, and recommendations
F Kluwe, R Michelet, A Mueller‐Schoell, C Maier, L Klopp‐Schulze, ...
Clinical Pharmacology & Therapeutics 109 (1), 29-36, 2021
462021
Exploring the use of serum‐derived small extracellular vesicles as liquid biopsy to study the induction of hepatic cytochromes P450 and organic anion transporting polypeptides
AD Rodrigues, M Van Dyk, MJ Sorich, A Fahmy, Z Useckaite, LA Newman, ...
Clinical Pharmacology & Therapeutics 110 (1), 248-258, 2021
432021
Physiologically based pharmacokinetic modeling to identify physiological and molecular characteristics driving variability in drug exposure
A Rowland, M Van Dyk, AM Hopkins, R Mounzer, TM Polasek, ...
Clinical Pharmacology & Therapeutics 104 (6), 1219-1228, 2018
332018
Efficacy and safety of NSAIDs in infants: a comprehensive review of the literature of the past 20 years
VC Ziesenitz, T Welzel, M van Dyk, P Saur, M Gorenflo, JN van den Anker
Pediatric Drugs 24 (6), 603-655, 2022
302022
Assessment of inter-racial variability in CYP3A4 activity and inducibility among healthy adult males of Caucasian and South Asian ancestries
M Van Dyk, JC Marshall, MJ Sorich, LS Wood, A Rowland
European journal of clinical pharmacology 74, 913-920, 2018
242018
A novel approach for the simultaneous quantification of 18 small molecule kinase inhibitors in human plasma: a platform for optimised KI dosing
M Van Dyk, JO Miners, G Kichenadasse, RA McKinnon, A Rowland
Journal of Chromatography B 1033, 17-26, 2016
212016
Targeted arginine metabolomics: A rapid, simple UPLC-QToF-MSE based approach for assessing the involvement of arginine metabolism in human disease
M Van Dyk, AA Mangoni, M McEvoy, JR Attia, MJ Sorich, A Rowland
Clinica Chimica Acta 447, 59-65, 2015
182015
Evaluation of modafinil as a perpetrator of metabolic drug–drug interactions using a model informed cocktail reaction phenotyping trial protocol
A Rowland, M Van Dyk, D Warncken, AA Mangoni, MJ Sorich, A Rowland
British journal of clinical pharmacology 84 (3), 501-509, 2018
152018
Effect of early adverse events on response and survival outcomes of advanced melanoma patients treated with vemurafenib or vemurafenib plus cobimetinib: A pooled analysis of …
AM Hopkins, M Van Dyk, A Rowland, MJ Sorich
Pigment cell & melanoma research 32 (4), 576-583, 2019
122019
Use of physiologically based pharmacokinetic modeling to identify physiological and molecular characteristics driving variability in axitinib exposure: a fresh approach to …
MJ Sorich, F Mutlib, M van Dyk, AM Hopkins, TM Polasek, JC Marshall, ...
The Journal of Clinical Pharmacology 59 (6), 872-879, 2019
122019
Steady-state pharmacokinetics of phentermine extended-release capsules.
G Groenewoud, R Schall, HK Hundt, FO Müller, M Van Dyk
International Journal of Clinical Pharmacology, Therapy, and Toxicology 31 …, 1993
101993
Combining therapeutic drug monitoring and pharmacokinetic modelling deconvolutes physiological and environmental sources of variability in clozapine exposure
KH Wills, SJ Behan, MJ Nance, JL Dawson, TM Polasek, AM Hopkins, ...
Pharmaceutics 14 (1), 47, 2021
92021
Validation of a 3-h sampling interval to assess variability in cytochrome P450 3A phenotype and the impact of induction and mechanism-based inhibition using midazolam as a …
M Van Dyk, AJ Kapetas, AM Hopkins, AD Rodrigues, M Vourvahis, ...
Frontiers in Pharmacology 10, 1120, 2019
62019
Physiologically-based pharmacokinetic modeling as an approach to evaluate the effect of covariates and drug-drug interactions on variability in epidermal growth factor receptor …
M Van Dyk, A Rowland
Translational Cancer Research 6 (Suppl 10), 2017
62017
PBPK modeling as an approach to evaluate the effect of covariates and drug-drug interactions on variability in EGFR kinase inhibitor exposure. Transl
M Van Dyk, A Rowland
Cancer Res 6, S1600-S1615, 2017
62017
Investigation of a possible pharmacokinetic interaction between nisoldipine and quinidine in healthy volunteers
R Schall, FO Müller, G Groenewoud, HKL Hundt, HG Luus, M van Dyk, ...
Drug Investigation 8, 162-170, 1994
61994
Simulation-based assessment of the impact of non-adherence on endoxifen target attainment in different tamoxifen dosing strategies
A Mueller-Schoell, L Klopp-Schulze, R Michelet, M van Dyk, TE Mürdter, ...
Pharmaceuticals 14 (2), 115, 2021
52021
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