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Lekha Jain
Lekha Jain
Research Fellow, University of Auckland
Verified email at auckland.ac.nz
Title
Cited by
Cited by
Year
TNF-α differentially regulates cell cycle genes in promyelocytic and granulocytic HL-60/S4 cells
EC Jacobson, L Jain, MH Vickers, AL Olins, DE Olins, JK Perry, ...
G3: Genes, Genomes, Genetics 9 (8), 2775-2786, 2019
102019
Differential expression of steroid hormone receptors and ten eleven translocation proteins in endometrial cancer cells
V Mahajan, P Gujral, L Jain, AP Ponnampalam
Frontiers in Oncology 12, 763464, 2022
72022
Re-thinking osteoarthritis pathogenesis: what can we learn (and what do we need to unlearn) from mouse models about the mechanisms involved in disease development
RC Poulsen, L Jain, N Dalbeth
Arthritis Research & Therapy 25 (1), 59, 2023
62023
IL-1β induces changes in expression of core circadian clock components PER2 and BMAL1 in primary human chondrocytes through the NMDA receptor/CREB and NF-κB signalling pathways
M Alhilali, JI Hearn, J Rong, L Jain, SM Bolam, AP Monk, JT Munro, ...
Cellular signalling 87, 110143, 2021
62021
Monosodium urate crystals alter the circadian clock in macrophages leading to loss of NLRP3 inflammasome repression: Implications for timing of the gout flare
D Popov, L Jain, M Alhilali, N Dalbeth, RC Poulsen
The FASEB Journal 37 (6), e22940, 2023
52023
Differential effects of hypoxia versus hyperoxia or physoxia on phenotype and energy metabolism in human chondrocytes from osteoarthritic compared to macroscopically normal …
L Jain, SM Bolam, AP Monk, JT Munro, E Chen, J Tamatea, N Dalbeth, ...
International Journal of Molecular Sciences 24 (8), 7532, 2023
52023
3D interactions with the growth hormone locus in cellular signalling and cancer-related pathways
L Jain, T Fadason, W Schierding, MH Vickers, JM O’Sullivan, JK Perry
Journal of Molecular Endocrinology 64 (4), 209-222, 2020
52020
REST, RCOR1 and RCOR2 expression is reduced in osteoarthritic chondrocytes and contributes to increasing MMP13 and ADAMTS5 expression through upregulating HES1
JGB Primrose, L Jain, M Alhilali, SM Bolam, AP Monk, JT Munro, ...
Cellular Signalling 109, 110800, 2023
22023
Phenotype and energy metabolism differ between osteoarthritic chondrocytes from male compared to female patients: Implications for sexual dimorphism in osteoarthritis development?
L Jain, CA Jardim, R Yulo, SM Bolam, AP Monk, JT Munro, R Pitto, ...
Osteoarthritis and Cartilage, 2023
12023
Concentration-dependent effects of leptin on osteoarthritis-associated changes in phenotype of human chondrocytes
JGB Primrose, L Jain, SM Bolam, AP Monk, JT Munro, N Dalbeth, ...
Connective Tissue Research 64 (5), 457-468, 2023
12023
Elevated glucose promotes MMP13 and ADAMTS5 production by osteoarthritic chondrocytes under oxygenated but not hypoxic conditions
L Jain, SM Bolam, P Monk, JT Munro, J Tamatea, N Dalbeth, RC Poulsen
Journal of Cellular Physiology, 2024
2024
OR01-04 The Growth Hormone Receptor Interacts With Transcriptional Regulator, HMGN1, Upon GH-induced Nuclear Translocation
L Jain, MH Vickers, B Jacob, MJ Middleditch, DA Chudakova, ...
Journal of the Endocrine Society 7 (Supplement_1), bvad114. 1086, 2023
2023
The growth hormone receptor interacts with transcriptional regulator HMGN1 upon GH-induced nuclear translocation
L Jain, MH Vickers, B Jacob, MJ Middleditch, DA Chudakova, ...
Journal of Cell Communication and Signaling 17 (3), 925-937, 2023
2023
SAT-303 3D Mapping of the Human Growth Hormone Locus Identifies Putative Regulatory Hubs for Genes Involved in Cellular Signalling and Cancer-Related Pathways
L Jain, T Fadason, W Schierding, MH Vickers, JM O’Sullivan, JK Perry
Journal of the Endocrine Society 4 (Supplement_1), SAT-303, 2020
2020
A genomic, proteomic and transcriptomic investigation into growth hormone actions
L Jain
PhD Thesis-University of Auckland, 2020
2020
Characterisation of growth hormone signal transduction in primary melanoma cell lines
KS Sousa, K Tran, S Kolekar, L Jain, Y Wang, PR Shepherd, J Perry
Annals of Oncology 30, v9, 2019
2019
TNF-α Differentially Regulates Cell Cycle Genes In Promyelocytic TNF-Differentially Regulates Cell Cycle Genes In Promyelocytic And Granulocytic HL-60/S4 Cells
EC Jacobson, L Jain, MH Vickers, AL Olins, DE Olins
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Articles 1–17