| Tocilizumab in patients admitted to hospital with COVID-19 (RECOVERY): a randomised, controlled, open-label, platform trial RECOVERY Collaborative Group Lancet (London, England) 397 (10285), 1637, 2021 | 1987* | 2021 |
| Synthetic lethal targeting of PTEN mutant cells with PARP inhibitors AM Mendes‐Pereira, SA Martin, R Brough, A McCarthy, JR Taylor, JS Kim, ... EMBO molecular medicine 1 (6‐7), 315-322, 2009 | 730 | 2009 |
| Word-frequency effects on short-term memory tasks: evidence for a redintegration process in immediate serial recall. C Hulme, S Roodenrys, R Schweickert, GDA Brown, S Martin, G Stuart Journal of Experimental Psychology: Learning, Memory, and Cognition 23 (5), 1217, 1997 | 634 | 1997 |
| RVX-208, an inhibitor of BET transcriptional regulators with selectivity for the second bromodomain S Picaud, C Wells, I Felletar, D Brotherton, S Martin, P Savitsky, ... Proceedings of the National Academy of Sciences 110 (49), 19754-19759, 2013 | 478 | 2013 |
| Dual kinase-bromodomain inhibitors for rationally designed polypharmacology P Ciceri, S Müller, A O'mahony, O Fedorov, P Filippakopoulos, JP Hunt, ... Nature chemical biology 10 (4), 305-312, 2014 | 367 | 2014 |
| Discovery and optimization of small-molecule ligands for the CBP/p300 bromodomains DA Hay, O Fedorov, S Martin, DC Singleton, C Tallant, C Wells, S Picaud, ... Journal of the American Chemical Society 136 (26), 9308-9319, 2014 | 325 | 2014 |
| Aspirin in patients admitted to hospital with COVID-19 (RECOVERY): a randomised, controlled, open-label, platform trial RECOVERY Collaborative Group Lancet (London, England) 399 (10320), 143, 2022 | 307* | 2022 |
| Functional genomic landscape of cancer-intrinsic evasion of killing by T cells KA Lawson, CM Sousa, X Zhang, E Kim, R Akthar, JJ Caumanns, Y Yao, ... Nature 586 (7827), 120-126, 2020 | 274 | 2020 |
| Mismatch repair deficient colorectal cancer in the era of personalized treatment M Hewish, CJ Lord, SA Martin, D Cunningham, A Ashworth Nature reviews Clinical oncology 7 (4), 197-208, 2010 | 263 | 2010 |
| Generation of a selective small molecule inhibitor of the CBP/p300 bromodomain for leukemia therapy S Picaud, O Fedorov, A Thanasopoulou, K Leonards, K Jones, J Meier, ... Cancer research 75 (23), 5106-5119, 2015 | 239 | 2015 |
| DNA polymerases as potential therapeutic targets for cancers deficient in the DNA mismatch repair proteins MSH2 or MLH1 SA Martin, N McCabe, M Mullarkey, R Cummins, DJ Burgess, ... Cancer cell 17 (3), 235-248, 2010 | 236 | 2010 |
| Methotrexate induces oxidative DNA damage and is selectively lethal to tumour cells with defects in the DNA mismatch repair gene MSH2 SA Martin, A McCarthy, LJ Barber, DJ Burgess, S Parry, CJ Lord, ... EMBO molecular medicine 1 (6‐7), 323-337, 2009 | 210 | 2009 |
| DNA repair deficiency as a therapeutic target in cancer SA Martin, CJ Lord, A Ashworth Current opinion in genetics & development 18 (1), 80-86, 2008 | 208 | 2008 |
| Therapeutic targeting of the DNA mismatch repair pathway SA Martin, CJ Lord, A Ashworth Clinical cancer research 16 (21), 5107-5113, 2010 | 186 | 2010 |
| Optimization of 3, 5-dimethylisoxazole derivatives as potent bromodomain ligands DS Hewings, O Fedorov, P Filippakopoulos, S Martin, S Picaud, A Tumber, ... Journal of medicinal chemistry 56 (8), 3217-3227, 2013 | 159 | 2013 |
| Discovery of novel small-molecule inhibitors of BRD4 using structure-based virtual screening LR Vidler, P Filippakopoulos, O Fedorov, S Picaud, S Martin, M Tomsett, ... Journal of medicinal chemistry 56 (20), 8073-8088, 2013 | 158 | 2013 |
| DNA mismatch repair and oxidative DNA damage: implications for cancer biology and treatment G Bridge, S Rashid, SA Martin Cancers 6 (3), 1597-1614, 2014 | 153 | 2014 |
| Selective targeting of the BRG/PB1 bromodomains impairs embryonic and trophoblast stem cell maintenance O Fedorov, J Castex, C Tallant, DR Owen, S Martin, M Aldeghi, ... Science advances 1 (10), e1500723, 2015 | 143 | 2015 |
| A Series of Potent CREBBP Bromodomain Ligands Reveals an Induced‐Fit Pocket Stabilized by a Cation–π Interaction TPC Rooney, P Filippakopoulos, O Fedorov, S Picaud, WA Cortopassi, ... Angewandte Chemie International Edition 53 (24), 6126-6130, 2014 | 131 | 2014 |
| Must boys be boys?: Ending sexual exploitation & abuse in UN Peacekeeping missions S Martin Refugees International, 2005 | 123 | 2005 |
