PSPC1 mediates TGF-β1 autocrine signalling and Smad2/3 target switching to promote EMT, stemness and metastasis HW Yeh, EC Hsu, SS Lee, YD Lang, YC Lin, CY Chang, SY Lee, DL Gu, ... Nature cell biology 20 (4), 479-491, 2018 | 165 | 2018 |
SLC25A39 is necessary for mitochondrial glutathione import in mammalian cells Y Wang, FS Yen, XG Zhu, RC Timson, R Weber, C Xing, Y Liu, B Allwein, ... Nature 599 (7883), 136-140, 2021 | 120 | 2021 |
A new switch for TGFβ in cancer HW Yeh, SS Lee, CY Chang, YD Lang, YS Jou Cancer research 79 (15), 3797-3805, 2019 | 101 | 2019 |
Pyrimidine metabolic rate limiting enzymes in poorly-differentiated hepatocellular carcinoma are signature genes of cancer stemness and associated with poor prognosis HW Yeh, SS Lee, CY Chang, CM Hu, YS Jou Oncotarget 8 (44), 77734, 2017 | 40 | 2017 |
PSPC1-interchanged interactions with PTK6 and β-catenin synergize oncogenic subcellular translocations and tumor progression YD Lang, HY Chen, CM Ho, JH Shih, EC Hsu, R Shen, YC Lee, JW Chen, ... Nature Communications 10 (1), 5716, 2019 | 31 | 2019 |
Metabolic-scale gene activation screens identify SLCO2B1 as a heme transporter that enhances cellular iron availability G Unlu, B Prizer, R Erdal, HW Yeh, EC Bayraktar, K Birsoy Molecular cell 82 (15), 2832-2843. e7, 2022 | 15 | 2022 |
PSPC1 potentiates TGF-β-dependent metastatic dissemination HW Yeh, YS Jou Molecular & Cellular Oncology 5 (4), e1472058, 2018 | 8 | 2018 |
Development of a mouse model expressing a bifunctional glutathione-synthesizing enzyme to study glutathione limitation in vivo RC Timson, A Khan, B Uygur, M Saad, HW Yeh, NL DelGaudio, R Weber, ... Journal of Biological Chemistry 300 (2), 2024 | 2 | 2024 |
A mouse model to study glutathione limitation in vivo RC Timson, A Khan, B Uygur, M Saad, HW Yeh, NL DelGaudio, R Weber, ... bioRxiv, 2024.01. 08.574722, 2024 | | 2024 |
PSPC1 is an activator to drive the epithelial-mesenchymal transition, stemness and TGF-beta metastatic switch Y Jou, H Yeh, Y Lang MOLECULAR BIOLOGY OF THE CELL 27, 2016 | | 2016 |