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Holst M. Halsey
Holst M. Halsey
Analytical Research & Development, Merck & Co. Inc.
Verified email at merck.com
Title
Cited by
Cited by
Year
Design of an in vitro biocatalytic cascade for the manufacture of islatravir
MA Huffman, A Fryszkowska, O Alvizo, M Borra-Garske, KR Campos, ...
Science 366 (6470), 1255-1259, 2019
4832019
Multi-column ultra-high performance liquid chromatography screening with chaotropic agents and computer-assisted separation modeling enables process development of new drug …
IAH Ahmad, W Chen, HM Halsey, A Klapars, J Limanto, GF Pirrone, ...
Analyst 144 (9), 2872-2880, 2019
402019
Revealing the inner workings of the power function algorithm in Charged Aerosol Detection: A simple and effective approach to optimizing power function value for quantitative …
IAH Ahmad, A Blasko, J Tam, N Variankaval, HM Halsey, R Hartman, ...
Journal of Chromatography A 1603, 1-7, 2019
322019
Generic gas chromatography flame ionization detection method using hydrogen as the carrier gas for the analysis of solvents in pharmaceuticals
F Bernardoni, HM Halsey, R Hartman, T Nowak, EL Regalado
Journal of pharmaceutical and biomedical analysis 165, 366-373, 2019
292019
Generic gas chromatography-flame ionization detection method for quantitation of volatile amines in pharmaceutical drugs and synthetic intermediates
GC Graffius, BM Jocher, D Zewge, HM Halsey, G Lee, F Bernardoni, X Bu, ...
Journal of Chromatography A 1518, 70-77, 2017
232017
Development and validation of ion-pairing HPLC-CAD chromatography for measurement of Islatravir’s phosphorylated intermediates
MJ Gunsch, EL Schwalm, CM Ouimet, HM Halsey, SE Hamilton, ...
Journal of Pharmaceutical and Biomedical Analysis 213, 114684, 2022
62022
Industry-wide collaboration toward an efficient and systematic approach to quantitative solvent analysis in drug substances
BF Mann, HM Halsey, MA Al-Sayah, A Kumar, T Nguyen, K Crossley, ...
ACS Sustainable Chemistry & Engineering 7 (22), 18517-18523, 2019
62019
Generic GC-FID method for quantitation of volatile amines in pharmaceutical drugs and synthetic intermediates
GC Graffius, BM Jocher, D Zewge, HM Halsey, G Lee, F Bernardoni, X Bu, ...
J. Chromatogr. A 1518, 70-77, 2017
52017
Gefapixant citrate (MK-7264) sulfonamide step speciation study: Investigation into precipitation–dissolution events during addition of chlorosulfonic acid
NR Rivera, RD Cohen, SW Zhang, ZEX Dance, HM Halsey, S Song, X Bu, ...
Organic Process Research & Development 27 (2), 286-294, 2023
22023
Cluster Preface: Biocatalysis
TK Hyster
Synlett 31 (03), 223-223, 2020
12020
Development of a Green and Sustainable Manufacturing Process for a Key Intermediate to Nemtabrutinib (MK-1026): Sequential Deprotonation–Lithiation as a Batch–Flow Process
DAL Otte, RT Larson, E Alwedi, T Armiger, Y Chen, CK Chung, J Corry, ...
Organic Process Research & Development, 2024
2024
Challenges with retention and recovery of impurities containing acidic moieties during analytical UHPLC method development and validation for gefapixant freebase
H Halsey, J Hall, C Huang, W Liu, P Parganiha, S Song, A Duran-Capece, ...
Journal of Pharmaceutical and Biomedical Analysis 237, 115772, 2024
2024
Developing Around Uncertainty in the Scale up and Tech Transfer of Flow Reactions with Highly Reactive Reagents
R Franklin, T Armiger, P Patel, D Otte, J Hall, R Larson, V Rodrigues, ...
2022 AIChE Annual Meeting, 2022
2022
Design of an in vitro biocatalytic cascade for the manufacture of islatravir (vol 366, pg 1255, 2019)
A Fryszkowska, O Alvizo, M Borra-Garske, KR Campos, PN Devine, ...
Science 368 (6488), 2020
2020
Generic GC-FID method for high-throughput analysis of residual solvents in pharmaceutical substances
T Nowak, F Bernardoni, H Halsey, A Makarov, E Regalado
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 258, 2019
2019
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