Design of an in vitro biocatalytic cascade for the manufacture of islatravir MA Huffman, A Fryszkowska, O Alvizo, M Borra-Garske, KR Campos, ... Science 366 (6470), 1255-1259, 2019 | 483 | 2019 |
Multi-column ultra-high performance liquid chromatography screening with chaotropic agents and computer-assisted separation modeling enables process development of new drug … IAH Ahmad, W Chen, HM Halsey, A Klapars, J Limanto, GF Pirrone, ... Analyst 144 (9), 2872-2880, 2019 | 40 | 2019 |
Revealing the inner workings of the power function algorithm in Charged Aerosol Detection: A simple and effective approach to optimizing power function value for quantitative … IAH Ahmad, A Blasko, J Tam, N Variankaval, HM Halsey, R Hartman, ... Journal of Chromatography A 1603, 1-7, 2019 | 32 | 2019 |
Generic gas chromatography flame ionization detection method using hydrogen as the carrier gas for the analysis of solvents in pharmaceuticals F Bernardoni, HM Halsey, R Hartman, T Nowak, EL Regalado Journal of pharmaceutical and biomedical analysis 165, 366-373, 2019 | 29 | 2019 |
Generic gas chromatography-flame ionization detection method for quantitation of volatile amines in pharmaceutical drugs and synthetic intermediates GC Graffius, BM Jocher, D Zewge, HM Halsey, G Lee, F Bernardoni, X Bu, ... Journal of Chromatography A 1518, 70-77, 2017 | 23 | 2017 |
Development and validation of ion-pairing HPLC-CAD chromatography for measurement of Islatravir’s phosphorylated intermediates MJ Gunsch, EL Schwalm, CM Ouimet, HM Halsey, SE Hamilton, ... Journal of Pharmaceutical and Biomedical Analysis 213, 114684, 2022 | 6 | 2022 |
Industry-wide collaboration toward an efficient and systematic approach to quantitative solvent analysis in drug substances BF Mann, HM Halsey, MA Al-Sayah, A Kumar, T Nguyen, K Crossley, ... ACS Sustainable Chemistry & Engineering 7 (22), 18517-18523, 2019 | 6 | 2019 |
Generic GC-FID method for quantitation of volatile amines in pharmaceutical drugs and synthetic intermediates GC Graffius, BM Jocher, D Zewge, HM Halsey, G Lee, F Bernardoni, X Bu, ... J. Chromatogr. A 1518, 70-77, 2017 | 5 | 2017 |
Gefapixant citrate (MK-7264) sulfonamide step speciation study: Investigation into precipitation–dissolution events during addition of chlorosulfonic acid NR Rivera, RD Cohen, SW Zhang, ZEX Dance, HM Halsey, S Song, X Bu, ... Organic Process Research & Development 27 (2), 286-294, 2023 | 2 | 2023 |
Cluster Preface: Biocatalysis TK Hyster Synlett 31 (03), 223-223, 2020 | 1 | 2020 |
Development of a Green and Sustainable Manufacturing Process for a Key Intermediate to Nemtabrutinib (MK-1026): Sequential Deprotonation–Lithiation as a Batch–Flow Process DAL Otte, RT Larson, E Alwedi, T Armiger, Y Chen, CK Chung, J Corry, ... Organic Process Research & Development, 2024 | | 2024 |
Challenges with retention and recovery of impurities containing acidic moieties during analytical UHPLC method development and validation for gefapixant freebase H Halsey, J Hall, C Huang, W Liu, P Parganiha, S Song, A Duran-Capece, ... Journal of Pharmaceutical and Biomedical Analysis 237, 115772, 2024 | | 2024 |
Developing Around Uncertainty in the Scale up and Tech Transfer of Flow Reactions with Highly Reactive Reagents R Franklin, T Armiger, P Patel, D Otte, J Hall, R Larson, V Rodrigues, ... 2022 AIChE Annual Meeting, 2022 | | 2022 |
Design of an in vitro biocatalytic cascade for the manufacture of islatravir (vol 366, pg 1255, 2019) A Fryszkowska, O Alvizo, M Borra-Garske, KR Campos, PN Devine, ... Science 368 (6488), 2020 | | 2020 |
Generic GC-FID method for high-throughput analysis of residual solvents in pharmaceutical substances T Nowak, F Bernardoni, H Halsey, A Makarov, E Regalado ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 258, 2019 | | 2019 |