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Denis Belitškin, Ph.D.
Denis Belitškin, Ph.D.
Icosagen Cell Factory OÜ
Verified email at icosagen.ee - Homepage
Title
Cited by
Cited by
Year
Deregulated hepsin protease activity confers oncogenicity by concomitantly augmenting HGF/MET signalling and disrupting epithelial cohesion
TA Tervonen, D Belitškin, SM Pant, JI Englund, E Marques, ...
Oncogene 35 (14), 1832-1846, 2016
482016
Data integration to prioritize drugs using genomics and curated data
R Louhimo, M Laakso, D Belitskin, J Klefström, R Lehtonen, S Hautaniemi
BioData mining 9, 1-13, 2016
212016
Hepsin regulates TGFβ signaling via fibronectin proteolysis
KJ Belitškin D, Pant SM, Munne P, Suleymanova I, Belitškina K, Hongisto HA ...
EMBO Rep. 2021 Sep 13:e52532. doi: 10.15252/embr.202152532. Epub ahead of …, 2021
12*2021
Oncogenic Ras Disrupts Epithelial Integrity by Activating the Transmembrane Serine Protease Hepsin
TA Tervonen, SM Pant, D Belitškin, JI Englund, K Närhi, C Haglund, ...
Cancer Research 81 (6), 1513-1527, 2021
112021
Analyzing the type II transmembrane serine protease hepsin-dependent basement membrane remodeling in 3D cell culture
SM Pant, D Belitskin, H Ala-Hongisto, J Klefström, TA Tervonen
Proteases and Cancer: Methods and Protocols, 169-178, 2018
92018
The inhibition of Akt-Pdpk1 interaction efficiently suppresses the growth of murine primary liver tumor cells
K Mäemets-Allas, D Belitškin, V Jaks
Biochemical and Biophysical Research Communications 474 (1), 118-125, 2016
72016
A label-retaining but unipotent cell population resides in biliary compartment of mammalian liver
J Viil, M Klaas, K Valter, D Belitškin, S Ilmjärv, V Jaks
Scientific reports 7 (1), 40322, 2017
52017
Hepsin promotes breast tumor growth signaling via the TGFβ‐EGFR axis
D Belitškin, P Munne, SM Pant, JM Anttila, I Suleymanova, K Belitškina, ...
Molecular oncology 18 (3), 547-561, 2024
22024
Development of therapeutic antibodies targeting the GLUT-1 transporter to restrict cancer cell growth
S Tahk, K Virumae, K Anton, P Hermet, R Pau, M Plaas, M Abel, ...
Cancer Research 84 (6_Supplement), 1876-1876, 2024
2024
Functional antibodies against multi span transmembrane proteins-revisiting the Warburg effect in cancer cells
S Tahk, K Virumäe, P Hermet, K Anton, M Abel, D Belitškin, L Galdieri, ...
Cancer Research 83 (7_Supplement), 6036-6036, 2023
2023
Hepsin promotes breast tumor growth signaling via TGF beta-EGFR axis
T Tervonen, D Belitskin, P Munne, S Pant, J Anttila, K Belitskina, ...
European Journal of Cancer 174, S98, 2022
2022
Patient derived explant culture (PDEC) as a model for treatment resistant ERα positive breast cancers
P Munne, I Räty, A Peura, L Patrikainen, D Belitskin, J Klefstrom
Cancer Research 82 (12_Supplement), 286-286, 2022
2022
Serine protease hepsin regulates tumor growth via TGFbeta-EGFR signaling axis
TA Tervonen, D Belitškin, P Munne, SM Pant, I Suleymanova, K Belitškina, ...
Cancer Research 82 (12_Supplement), 834-834, 2022
2022
The role of type II serine protease hepsin in breast cancer signaling
D Belitškin
Helsingin yliopisto, 2022
2022
Abstract LB-204: Oncogenic Ras signaling requires serine protease hepsin to induce invasive breast cancer phenotype
SM Pant, T Tervonen, D Belitskin, J Englund, E Verschuren, P Kovanen, ...
Cancer Research 80 (16_Supplement), LB-204-LB-204, 2020
2020
Ras recruits oncogenic serine protease hepsin to disrupt mammary epithelial integrity
TA Tervonen, SM Pant, D Belitskin, J Englund, K Närhi, E Verschuren, ...
Cancer Research 79 (13_Supplement), 3484-3484, 2019
2019
The Cell‐Surface, Transmembrane Serine Protease Hepsin: Discovery, Function and Role in Cancer
D Belitškin, SM Pant, T Tervonen, J Klefström
Extracellular Targeting of Cell Signaling in Cancer: Strategies Directed at …, 2018
2018
REGULATION OF ADULT STEM CELLS IN MOUSE LIVER TUMORIGENESIS
D Belitškin
Supplementary documentation for” Data integration to prioritize drugs using genomics and curated data “
R Louhimo, M Laakso, D Belitskin, J Klefström, R Lehtonen, S Hautaniemi
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Articles 1–19