K.C. Allen Chan
K.C. Allen Chan
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Noninvasive prenatal diagnosis of fetal chromosomal aneuploidy by massively parallel genomic sequencing of DNA in maternal plasma
RWK Chiu, KCA Chan, Y Gao, VYM Lau, W Zheng, TY Leung, CHF Foo, ...
Proceedings of the National Academy of Sciences 105 (51), 20458-20463, 2008
Maternal plasma DNA sequencing reveals the genome-wide genetic and mutational profile of the fetus
YMD Lo, KCA Chan, H Sun, EZ Chen, P Jiang, FMF Lun, YW Zheng, ...
Science translational medicine 2 (61), 61ra91-61ra91, 2010
Non-invasive prenatal assessment of trisomy 21 by multiplexed maternal plasma DNA sequencing: large scale validity study
RWK Chiu, R Akolekar, YWL Zheng, TY Leung, H Sun, KCA Chan, ...
Bmj 342, 2011
Size distributions of maternal and fetal DNA in maternal plasma
KCA Chan, J Zhang, ABY Hui, N Wong, TK Lau, TN Leung, KW Lo, ...
Clinical chemistry 50 (1), 88-92, 2004
Convalescent plasma treatment reduced mortality in patients with severe pandemic influenza A (H1N1) 2009 virus infection
IFN Hung, KKW To, CK Lee, KL Lee, K Chan, WW Yan, R Liu, CL Watt, ...
Clinical Infectious Diseases 52 (4), 447-456, 2011
Effects of early corticosteroid treatment on plasma SARS-associated Coronavirus RNA concentrations in adult patients
N Lee, KCA Chan, DS Hui, EKO Ng, A Wu, RWK Chiu, VWS Wong, ...
Journal of clinical virology 31 (4), 304-309, 2004
Digital PCR for the molecular detection of fetal chromosomal aneuploidy
YMD Lo, FMF Lun, KCA Chan, NBY Tsui, KC Chong, TK Lau, TY Leung, ...
Proceedings of the National Academy of Sciences 104 (32), 13116-13121, 2007
Microfluidics digital PCR reveals a higher than expected fraction of fetal DNA in maternal plasma
FMF Lun, RWK Chiu, KC Allen Chan, T Yeung Leung, T Kin Lau, ...
Clinical chemistry 54 (10), 1664-1672, 2008
Lengthening and shortening of plasma DNA in hepatocellular carcinoma patients
P Jiang, CWM Chan, KCA Chan, SH Cheng, J Wong, VWS Wong, ...
Proceedings of the National Academy of Sciences 112 (11), E1317-E1325, 2015
Plasma DNA tissue mapping by genome-wide methylation sequencing for noninvasive prenatal, cancer, and transplantation assessments
K Sun, P Jiang, KCA Chan, J Wong, YKY Cheng, RHS Liang, W Chan, ...
Proceedings of the National Academy of Sciences 112 (40), E5503-E5512, 2015
Cancer genome scanning in plasma: detection of tumor-associated copy number aberrations, single-nucleotide variants, and tumoral heterogeneity by massively parallel sequencing
KCA Chan, P Jiang, YWL Zheng, GJW Liao, H Sun, J Wong, SSN Siu, ...
Clinical chemistry 59 (1), 211-224, 2013
Analysis of plasma Epstein–Barr virus DNA to screen for nasopharyngeal cancer
KCA Chan, JKS Woo, A King, BCY Zee, WKJ Lam, SL Chan, SWI Chu, ...
New England Journal of Medicine 377 (6), 513-522, 2017
Single-molecule detection of epidermal growth factor receptor mutations in plasma by microfluidics digital PCR in non–small cell lung cancer patients
TKF Yung, KC Chan, TSK Mok, J Tong, KF To, YM Lo
Clinical Cancer Research 15 (6), 2076-2084, 2009
Noninvasive prenatal diagnosis of monogenic diseases by digital size selection and relative mutation dosage on DNA in maternal plasma
FMF Lun, NBY Tsui, KCA Chan, TY Leung, TK Lau, P Charoenkwan, ...
Proceedings of the National Academy of Sciences 105 (50), 19920-19925, 2008
Noninvasive prenatal diagnosis of fetal trisomy 18 and trisomy 13 by maternal plasma DNA sequencing
EZ Chen, RWK Chiu, H Sun, R Akolekar, KCA Chan, TY Leung, P Jiang, ...
PloS one 6 (7), e21791, 2011
Hypermethylated RASSF1A in Maternal Plasma: A Universal Fetal DNA Marker that Improves the Reliability of Noninvasive Prenatal Diagnosis
KCA Chan, C Ding, A Gerovassili, SW Yeung, RWK Chiu, TN Leung, ...
Clinical chemistry 52 (12), 2211-2218, 2006
Noninvasive detection of cancer-associated genome-wide hypomethylation and copy number aberrations by plasma DNA bisulfite sequencing
KCA Chan, P Jiang, CWM Chan, K Sun, J Wong, EP Hui, SL Chan, ...
Proceedings of the National Academy of Sciences 110 (47), 18761-18768, 2013
Plasma Epstein-Barr viral deoxyribonucleic acid quantitation complements tumor-node-metastasis staging prognostication in nasopharyngeal carcinoma
S Leung, B Zee, BB Ma, EP Hui, F Mo, M Lai, KCA Chan, LYS Chan, ...
Journal of clinical oncology 24 (34), 5414-5418, 2006
Hyperimmune IV immunoglobulin treatment: a multicenter double-blind randomized controlled trial for patients with severe 2009 influenza A (H1N1) infection
IFN Hung, KKW To, CK Lee, KL Lee, WW Yan, K Chan, WM Chan, ...
Chest 144 (2), 464-473, 2013
Size-based molecular diagnostics using plasma DNA for noninvasive prenatal testing
SCY Yu, KCA Chan, YWL Zheng, P Jiang, GJW Liao, H Sun, R Akolekar, ...
Proceedings of the National Academy of Sciences 111 (23), 8583-8588, 2014
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