In vitro modulatory effects of Andrographis paniculata, Centella asiatica and Orthosiphon stamineus on cytochrome P450 2C19 (CYP2C19) Y Pan, BA Abd-Rashid, Z Ismail, R Ismail, JW Mak, PCK Pook, HM Er, ... Journal of ethnopharmacology 133 (2), 881-887, 2011 | 72 | 2011 |
In vitro modulatory effects on three major human cytochrome P450 enzymes by multiple active constituents and extracts of Centella asiatica Y Pan, BA Abd-Rashid, Z Ismail, R Ismail, JW Mak, PCK Pook, HM Er, ... Journal of ethnopharmacology 130 (2), 275-283, 2010 | 71 | 2010 |
Recent insights on anti-dengue virus (DENV) medicinal plants: review on in vitro, in vivo and in silico discoveries SYM Lim, JY Chieng, Y Pan All Life 14 (1), 1-33, 2021 | 49 | 2021 |
In vitro determination of the effect of Andrographis paniculata extracts and andrographolide on human hepatic cytochrome P450 activities Y Pan, BA Abd-Rashid, Z Ismail, R Ismail, JW Mak, PCK Pook, HM Er, ... Journal of natural medicines 65, 440-447, 2011 | 42 | 2011 |
Current high-throughput approaches of screening modulatory effects of xenobiotics on cytochrome P450 (CYP) enzymes YT Ung, CE Ong, Y Pan High-throughput 7 (4), 29, 2018 | 41 | 2018 |
Current updates on the in vivo assessment of zinc oxide nanoparticles toxicity using animal models CL Chong, CM Fang, SY Pung, CE Ong, YF Pung, C Kong, Y Pan BioNanoScience 11 (2), 590-620, 2021 | 39 | 2021 |
Khat (Catha edulis) and Obesity: A Scoping Review of Animal and Human Studies MA Alshagga, MA Alshawsh, A Seyedan, A Alsalahi, Y Pan, ... Annals of Nutrition and Metabolism 69 (3-4), 200-211, 2017 | 35 | 2017 |
Heterologous Expression of Human Cytochromes P450 2D6 and CYP3A4 in Escherichia coli and Their Functional Characterization Y Pan, BA Abd-Rashid, Z Ismail, R Ismail, JW Mak, CE Ong The protein journal 30, 581-591, 2011 | 35 | 2011 |
Cytochrome P450 genotypeguided drug therapies: an update on current states AN Dong, BH Tan, Y Pan, CE Ong Clinical and Experimental Pharmacology and Physiology 45 (10), 991-1001, 2018 | 33 | 2018 |
In vitro effects of active constituents and extracts of Orthosiphon stamineus on the activities of three major human cDNA-expressed cytochrome P450 enzymes Y Pan, BA Abd-Rashid, Z Ismail, R Ismail, JW Mak, PCK Pook, HM Er, ... Chemico-biological interactions 190 (1), 1-8, 2011 | 30 | 2011 |
Functional role of Ile264 in CYP2C8: mutations affect haem incorporation and catalytic activity R Singh, JG Ting, Y Pan, LK Teh, R Ismail, CE Ong Drug metabolism and pharmacokinetics 23 (3), 165-174, 2008 | 30 | 2008 |
Functional and structural characterisation of common cytochrome P450 2D6 allelic variants—roles of Pro34 and Thr107 in catalysis and inhibition AN Dong, N Ahemad, Y Pan, UD Palanisamy, BC Yiap, CE Ong Naunyn-Schmiedeberg's Archives of Pharmacology 392, 1015-1029, 2019 | 23 | 2019 |
In vitro approaches to investigate cytochrome P450 activities: update on current status and their applicability CE Ong, Y Pan, JW Mak, R Ismail Expert opinion on drug metabolism & toxicology 9 (9), 1097-1113, 2013 | 22 | 2013 |
Effect of 95% ethanol khat extract and cathinone on in vitro human recombinant cytochrome P450 (CYP) 2C9, CYP2D6, and CYP3A4 activity SYM Lim, AR Binti Azidin, YT Ung, M Al-Shagga, MA Alshawsh, ... European journal of drug metabolism and pharmacokinetics 44, 423-431, 2019 | 21 | 2019 |
Effect of eurycomanone on cytochrome P450 isoforms CYP1A2, CYP2A6, CYP2C8, CYP2C9, CYP2C19, CYP2E1 and CYP3A4 in vitro Y Pan, KH Tiong, BA Abd-Rashid, Z Ismail, R Ismail, JW Mak, CE Ong Journal of natural medicines 68, 402-406, 2014 | 20 | 2014 |
Inhibitory effects of cytochrome P450 enzymes CYP2C8, CYP2C9, CYP2C19 and CYP3A4 by Labisia pumila extracts Y Pan, KH Tiong, BA Abd-Rashid, Z Ismail, R Ismail, JW Mak, CE Ong Journal of ethnopharmacology 143 (2), 586-591, 2012 | 20 | 2012 |
Cytochrome P450 4B1 (CYP4B1) as a target in cancer treatment SYM Lim, M Alshagga, CE Ong, JY Chieng, Y Pan Human & experimental toxicology 39 (6), 785-796, 2020 | 19 | 2020 |
In vitro effect of important herbal active constituents on human cytochrome P450 1A2 (CYP1A2) activity Y Pan, KH Tiong, BA Abd-Rashid, Z Ismail, R Ismail, JW Mak, CE Ong Phytomedicine 21 (12), 1645-1650, 2014 | 18 | 2014 |
In vitro and In silico studies of interactions of cathinone with human recombinant cytochrome P450 CYP (1A2), CYP2A6, CYP2B6, CYP2C8, CYP2C19, CYP2E1, CYP2J2, and CYP3A5 SYM Lim, JSE Loo, M Alshagga, MA Alshawsh, CE Ong, Y Pan Toxicology Reports 9, 759-768, 2022 | 17 | 2022 |
The Cyp2r1 enzyme: structure, function, enzymatic properties and genetic polymorphism AN Dong, BH Tan, Y Pan, CE Ong Journal of Pharmacy & Pharmaceutical Sciences 24, 94-112, 2021 | 17 | 2021 |