Search-and-replace genome editing without double-strand breaks or donor DNA AV Anzalone, PB Randolph, JR Davis, AA Sousa, LW Koblan, JM Levy, ... Nature 576 (7785), 149-157, 2019 | 3404 | 2019 |
Genome editing with CRISPR–Cas nucleases, base editors, transposases and prime editors AV Anzalone, LW Koblan, DR Liu Nature biotechnology 38 (7), 824-844, 2020 | 1543 | 2020 |
Prime genome editing in rice and wheat Q Lin, Y Zong, C Xue, S Wang, S Jin, Z Zhu, Y Wang, AV Anzalone, ... Nature biotechnology 38 (5), 582-585, 2020 | 649 | 2020 |
Super-multiplex vibrational imaging L Wei, Z Chen, L Shi, R Long, AV Anzalone, L Zhang, F Hu, R Yuste, ... Nature 544 (7651), 465-470, 2017 | 427 | 2017 |
Engineered pegRNAs improve prime editing efficiency JW Nelson, PB Randolph, SP Shen, KA Everette, PJ Chen, AV Anzalone, ... Nature biotechnology 40 (3), 402-410, 2022 | 363 | 2022 |
Programmable deletion, replacement, integration and inversion of large DNA sequences with twin prime editing AV Anzalone, XD Gao, CJ Podracky, AT Nelson, LW Koblan, A Raguram, ... Nature biotechnology 40 (5), 731-740, 2022 | 283 | 2022 |
Efficient C• G-to-G• C base editors developed using CRISPRi screens, target-library analysis, and machine learning LW Koblan, M Arbab, MW Shen, JA Hussmann, AV Anzalone, JL Doman, ... Nature biotechnology 39 (11), 1414-1425, 2021 | 149 | 2021 |
PrimeDesign software for rapid and simplified design of prime editing guide RNAs JY Hsu, J Grünewald, R Szalay, J Shih, AV Anzalone, KC Lam, MW Shen, ... Nature Communications 12 (1), 1034, 2021 | 136 | 2021 |
A common diaryl ether intermediate for the gram-scale synthesis of oxazine and xanthene fluorophores. AV Anzalone, TY Wang, Z Chen, VW Cornish Angewandte Chemie International Edition 52 (2), 2013 | 53 | 2013 |
Discovery of a potent inhibitor of anaplastic lymphoma kinase with in vivo antitumor activity GR Ott, R Tripathy, M Cheng, R McHugh, AV Anzalone, TL Underiner, ... Acs Medicinal Chemistry Letters 1 (9), 493-498, 2010 | 47 | 2010 |
Efficient prime editing in mouse brain, liver and heart with dual AAVs JR Davis, S Banskota, JM Levy, GA Newby, X Wang, AV Anzalone, ... Nature biotechnology 42 (2), 253-264, 2024 | 44 | 2024 |
Novel 2, 3, 4, 5-tetrahydro-benzo [d] azepine derivatives of 2, 4-diaminopyrimidine, selective and orally bioavailable ALK inhibitors with antitumor efficacy in ALCL mouse models EF Mesaros, JP Burke, JD Parrish, BJ Dugan, AV Anzalone, TS Angeles, ... Bioorganic & medicinal chemistry letters 21 (1), 463-466, 2011 | 38 | 2011 |
Reprogramming eukaryotic translation with ligand-responsive synthetic RNA switches AV Anzalone, AJ Lin, S Zairis, R Rabadan, VW Cornish Nature methods 13 (5), 453-458, 2016 | 34 | 2016 |
Interrogation of Eukaryotic Stop Codon Readthrough Signals by in Vitro RNA Selection AV Anzalone, S Zairis, AJ Lin, R Rabadan, VW Cornish Biochemistry 58 (8), 1167-1178, 2019 | 31 | 2019 |
Synthesis of photoactivatable azido-acyl caged oxazine fluorophores for live-cell imaging AV Anzalone, Z Chen, VW Cornish Chemical communications 52 (60), 9442-9445, 2016 | 20 | 2016 |
A prime editor mouse to model a broad spectrum of somatic mutations in vivo ZA Ely, N Mathey-Andrews, S Naranjo, SI Gould, KL Mercer, GA Newby, ... Nature biotechnology 42 (3), 424-436, 2024 | 14 | 2024 |
Synthetic studies toward 3-(Acylamino)-1H-indazoles and development of a one-pot, Microwave-assisted, oxadiazole condensation/Boulton-Katritzky rearrangement GR Ott, AV Anzalone Synlett 2011 (20), 3018-3022, 2011 | 14 | 2011 |
Methods and compositions for prime editing nucleotide sequences DR Liu, AV Anzalone, G Newby, K Everette US Patent 11,447,770, 2022 | 13 | 2022 |
Programmable large DNA deletion, replacement, integration, and inversion with twin prime editing and site-specific recombinases AV Anzalone, XD Gao, CJ Podracky, AT Nelson, LW Koblan, A Raguram, ... BioRxiv, 2021.11. 01.466790, 2021 | 12 | 2021 |
Methods and compositions for prime editing nucleotide sequences DR Liu, AV Anzalone, JW Nelson US Patent 11,643,652, 2023 | 9 | 2023 |