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Andrew Anzalone
Andrew Anzalone
Broad Institute of MIT and Harvard
Verified email at broadinstitute.org
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Cited by
Year
Search-and-replace genome editing without double-strand breaks or donor DNA
AV Anzalone, PB Randolph, JR Davis, AA Sousa, LW Koblan, JM Levy, ...
Nature 576 (7785), 149-157, 2019
34042019
Genome editing with CRISPR–Cas nucleases, base editors, transposases and prime editors
AV Anzalone, LW Koblan, DR Liu
Nature biotechnology 38 (7), 824-844, 2020
15432020
Prime genome editing in rice and wheat
Q Lin, Y Zong, C Xue, S Wang, S Jin, Z Zhu, Y Wang, AV Anzalone, ...
Nature biotechnology 38 (5), 582-585, 2020
6492020
Super-multiplex vibrational imaging
L Wei, Z Chen, L Shi, R Long, AV Anzalone, L Zhang, F Hu, R Yuste, ...
Nature 544 (7651), 465-470, 2017
4272017
Engineered pegRNAs improve prime editing efficiency
JW Nelson, PB Randolph, SP Shen, KA Everette, PJ Chen, AV Anzalone, ...
Nature biotechnology 40 (3), 402-410, 2022
3632022
Programmable deletion, replacement, integration and inversion of large DNA sequences with twin prime editing
AV Anzalone, XD Gao, CJ Podracky, AT Nelson, LW Koblan, A Raguram, ...
Nature biotechnology 40 (5), 731-740, 2022
2832022
Efficient C• G-to-G• C base editors developed using CRISPRi screens, target-library analysis, and machine learning
LW Koblan, M Arbab, MW Shen, JA Hussmann, AV Anzalone, JL Doman, ...
Nature biotechnology 39 (11), 1414-1425, 2021
1492021
PrimeDesign software for rapid and simplified design of prime editing guide RNAs
JY Hsu, J Grünewald, R Szalay, J Shih, AV Anzalone, KC Lam, MW Shen, ...
Nature Communications 12 (1), 1034, 2021
1362021
A common diaryl ether intermediate for the gram-scale synthesis of oxazine and xanthene fluorophores.
AV Anzalone, TY Wang, Z Chen, VW Cornish
Angewandte Chemie International Edition 52 (2), 2013
532013
Discovery of a potent inhibitor of anaplastic lymphoma kinase with in vivo antitumor activity
GR Ott, R Tripathy, M Cheng, R McHugh, AV Anzalone, TL Underiner, ...
Acs Medicinal Chemistry Letters 1 (9), 493-498, 2010
472010
Efficient prime editing in mouse brain, liver and heart with dual AAVs
JR Davis, S Banskota, JM Levy, GA Newby, X Wang, AV Anzalone, ...
Nature biotechnology 42 (2), 253-264, 2024
442024
Novel 2, 3, 4, 5-tetrahydro-benzo [d] azepine derivatives of 2, 4-diaminopyrimidine, selective and orally bioavailable ALK inhibitors with antitumor efficacy in ALCL mouse models
EF Mesaros, JP Burke, JD Parrish, BJ Dugan, AV Anzalone, TS Angeles, ...
Bioorganic & medicinal chemistry letters 21 (1), 463-466, 2011
382011
Reprogramming eukaryotic translation with ligand-responsive synthetic RNA switches
AV Anzalone, AJ Lin, S Zairis, R Rabadan, VW Cornish
Nature methods 13 (5), 453-458, 2016
342016
Interrogation of Eukaryotic Stop Codon Readthrough Signals by in Vitro RNA Selection
AV Anzalone, S Zairis, AJ Lin, R Rabadan, VW Cornish
Biochemistry 58 (8), 1167-1178, 2019
312019
Synthesis of photoactivatable azido-acyl caged oxazine fluorophores for live-cell imaging
AV Anzalone, Z Chen, VW Cornish
Chemical communications 52 (60), 9442-9445, 2016
202016
A prime editor mouse to model a broad spectrum of somatic mutations in vivo
ZA Ely, N Mathey-Andrews, S Naranjo, SI Gould, KL Mercer, GA Newby, ...
Nature biotechnology 42 (3), 424-436, 2024
142024
Synthetic studies toward 3-(Acylamino)-1H-indazoles and development of a one-pot, Microwave-assisted, oxadiazole condensation/Boulton-Katritzky rearrangement
GR Ott, AV Anzalone
Synlett 2011 (20), 3018-3022, 2011
142011
Methods and compositions for prime editing nucleotide sequences
DR Liu, AV Anzalone, G Newby, K Everette
US Patent 11,447,770, 2022
132022
Programmable large DNA deletion, replacement, integration, and inversion with twin prime editing and site-specific recombinases
AV Anzalone, XD Gao, CJ Podracky, AT Nelson, LW Koblan, A Raguram, ...
BioRxiv, 2021.11. 01.466790, 2021
122021
Methods and compositions for prime editing nucleotide sequences
DR Liu, AV Anzalone, JW Nelson
US Patent 11,643,652, 2023
92023
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