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Saverio Gentile
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Cited by
Year
Voltage-gated ion channels in cancer cell proliferation
VR Rao, M Perez-Neut, S Kaja, S Gentile
Cancers 7 (2), 849-875, 2015
2012015
Rapid signaling at the plasma membrane by a nuclear receptor for thyroid hormone
NM Storey, S Gentile, H Ullah, A Russo, M Muessel, C Erxleben, ...
Proceedings of the National Academy of Sciences 103 (13), 5197-5201, 2006
1382006
Cyclosporin and Timothy syndrome increase mode 2 gating of CaV1. 2 calcium channels through aberrant phosphorylation of S6 helices
C Erxleben, Y Liao, S Gentile, D Chin, C Gomez-Alegria, Y Mori, ...
Proceedings of the National Academy of Sciences 103 (10), 3932-3937, 2006
1332006
A rapid cytoplasmic mechanism for PI3 kinase regulation by the nuclear thyroid hormone receptor, TRß, and genetic evidence for its role in the maturation of mouse hippocampal …
DLA Negin P. Martin, Ezequiel Marron Fernandez de Velasco, Fengxia Mizuno ...
Endocrinology, 2013-2058, 2014
78*2014
Potassium channel activation inhibits proliferation of breast cancer cells by activating a senescence program
K Lansu, S Gentile
Cell death & disease 4 (6), e652-e652, 2013
732013
Potassium channel activity controls breast cancer metastasis by affecting β-catenin signaling
EK Breuer, D Fukushiro-Lopes, A Dalheim, M Burnette, J Zartman, S Kaja, ...
Cell death & disease 10 (3), 180, 2019
722019
Rac GTPase signaling through the PP5 protein phosphatase
S Gentile, T Darden, C Erxleben, C Romeo, A Russo, N Martin, S Rossie, ...
Proceedings of the National Academy of Sciences 103 (13), 5202-5206, 2006
542006
The human ERG1 channel polymorphism, K897T, creates a phosphorylation site that inhibits channel activity
S Gentile, N Martin, E Scappini, J Williams, C Erxleben, DL Armstrong
Proceedings of the National Academy of Sciences 105 (38), 14704-14708, 2008
522008
Preclinical study of a Kv11. 1 potassium channel activator as antineoplastic approach for breast cancer
DF Fukushiro-Lopes, AD Hegel, V Rao, D Wyatt, A Baker, EK Breuer, ...
Oncotarget 9 (3), 3321, 2018
452018
Caveolin-1 controls mitochondrial damage and ROS production by regulating fission-fusion dynamics and mitophagy
Y Jiang, S Krantz, X Qin, S Li, H Gunasekara, YM Kim, A Zimnicka, M Bae, ...
Redox Biology 52, 102304, 2022
392022
(+)-Strebloside-induced cytotoxicity in ovarian cancer cells is mediated through cardiac glycoside signaling networks
WL Chen, Y Ren, J Ren, C Erxleben, ME Johnson, S Gentile, ...
Journal of natural products 80 (3), 659-669, 2017
382017
Activation of hERG3 channel stimulates autophagy and promotes cellular senescence in melanoma
M Perez-Neut, L Haar, V Rao, S Santha, K Lansu, B Rana, WK Jones, ...
Oncotarget 7 (16), 21991, 2016
382016
Multiomic analysis identifies CPT1A as a potential therapeutic target in platinum-refractory, high-grade serous ovarian cancer
D Huang, S Chowdhury, H Wang, SR Savage, RG Ivey, JJ Kennedy, ...
Cell Reports Medicine 2 (12), 2021
322021
Stimulation of hERG1 channel activity promotes a calcium-dependent degradation of cyclin E2, but not cyclin E1, in breast cancer cells
M Perez-Neut, A Shum, BD Cuevas, R Miller, S Gentile
Oncotarget 6 (3), 1631, 2015
302015
hERG1/Kv11. 1 activation stimulates transcription of p21waf/cip in breast cancer cells via a calcineurin-dependent mechanism
M Perez-Neut, VR Rao, S Gentile
Oncotarget 7 (37), 58893, 2016
292016
Repurposing Kir6/SUR2 channel activator minoxidil to arrests growth of gynecologic cancers
D Fukushiro-Lopes, AD Hegel, A Russo, V Senyuk, M Liotta, GC Beeson, ...
Frontiers in Pharmacology 11, 577, 2020
172020
hERG1 potassium channel in cancer cells: a tool to reprogram immortality
S Gentile
European Biophysics Journal 45, 649-655, 2016
152016
MEKK2 regulates paxillin ubiquitylation and localization in MDA-MB 231 breast cancer cells
M Ameka, MP Kahle, M Perez-Neut, S Gentile, AA Mirza, BD Cuevas
Biochemical Journal 464 (1), 99-108, 2014
142014
Ion channels in breast cancer: From signaling to therapy
D Jonathan, H Josh, DF Fukushiro-Lopes, D Laczynski, S Gentile
Breast Cancer Biol. Med 10, 66172, 2017
132017
Ion channels in aging and aging-related diseases
V Rao, S Kaja, S Gentile
Molecular Mechanisms of the Aging Process and Rejuvenation, 37, 2016
112016
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Articles 1–20