Cathepsin G inhibition by Serpinb1 and Serpinb6 prevents programmed necrosis in neutrophils and monocytes and reduces GSDMD-driven inflammation SS Burgener, NGF Leborgne, SJ Snipas, GS Salvesen, PI Bird, ... Cell reports 27 (12), 3646-3656. e5, 2019 | 187 | 2019 |
The NLRP3 inflammasome triggers sterile neuroinflammation and Alzheimer’s disease MT Milner, M Maddugoda, J Götz, SS Burgener, K Schroder Current Opinion in Immunology 68, 116-124, 2021 | 108 | 2021 |
Neutrophil extracellular traps in host defense SS Burgener, K Schroder Cold Spring Harbor perspectives in biology 12 (7), a037028, 2020 | 108 | 2020 |
miR-19b enhances proliferation and apoptosis resistance via the EGFR signaling pathway by targeting PP2A and BIM in non-small cell lung cancer U Baumgartner, F Berger, A Hashemi Gheinani, SS Burgener, ... Molecular cancer 17, 1-15, 2018 | 86 | 2018 |
Cytosolic PCNA interacts with p47phox and controls NADPH oxidase NOX2 activation in neutrophils D Ohayon, A De Chiara, PMC Dang, N Thieblemont, S Chatfield, ... Journal of Experimental Medicine 216 (11), 2669-2687, 2019 | 32 | 2019 |
Caspase-4 dimerisation and D289 auto-processing elicit an interleukin-1β-converting enzyme AH Chan, SS Burgener, K Vezyrgiannis, X Wang, J Acklam, JB Von Pein, ... Life Science Alliance 6 (10), 2023 | 14 | 2023 |
SCIMP is a spatiotemporal transmembrane scaffold for Erk1/2 to direct pro-inflammatory signaling in TLR-activated macrophages RM Lucas, L Liu, JEB Curson, YWH Koh, N Tuladhar, ND Condon, ... Cell Reports 36 (10), 2021 | 12 | 2021 |
Transgenic mice expressing human proteinase 3 exhibit sustained neutrophil-associated peritonitis KR Martin, M Pederzoli-Ribeil, E Pacreau, SS Burgener, A Dahdah, ... The Journal of Immunology 199 (11), 3914-3924, 2017 | 12 | 2017 |
Chronic cigarette smoke exposure and pneumococcal infection induce oropharyngeal microbiota dysbiosis and contribute to long-lasting lung damage in mice M Hilty, TM Wüthrich, A Godel, R Adelfio, S Aebi, SS Burgener, ... Microbial genomics 6 (12), e000485, 2020 | 11 | 2020 |
Myeloid conditional deletion and transgenic models reveal a threshold for the neutrophil survival factor Serpinb1 SS Burgener, M Baumann, P Basilico, E Remold-O’Donnell, IP Touw, ... Biological chemistry 397 (9), 897-905, 2016 | 10 | 2016 |
Serpinb6 prevents programmed necrosis in neutrophils and monocytes and reduces GSDMD-driven inflammation SS Burgener, NGF Leborgne, SJ Snipas, GS Salvesen, PI Bird, ... Cell Rep 27 (3646-3656), e5, 2019 | 8 | 2019 |
Placental inflammasome signaling: Protection for mother and baby SS Burgener, K Schroder Journal of Experimental Medicine 218 (1), 2021 | 6 | 2021 |
Granule leakage induces cell-intrinsic, granzyme b-mediated apoptosis in mast cells SS Burgener, M Brügger, NGF Leborgne, S Sollberger, P Basilico, ... Frontiers in cell and developmental biology 9, 630166, 2021 | 5 | 2021 |
Isolation and culture of pure adult mouse microglia and astrocytes for in vitro characterization and analyses MT Milner, GMEP Lawrence, CL Holley, LG Bodea, J Götz, SS Burgener, ... STAR protocols 3 (2), 101295, 2022 | 4 | 2022 |
The genetic background of mice influences the effects of cigarette smoke on onset and severity of experimental autoimmune encephalomyelitis G Enzmann, R Adelfio, A Godel, N Haghayegh Jahromi, S Tietz, ... International journal of molecular sciences 20 (6), 1433, 2019 | 4 | 2019 |
NLRP12 interacts with NLRP3 to block the activation of the human NLRP3 inflammasome JR Coombs, A Zamoshnikova, CL Holley, MP Maddugoda, DET Teo, ... Science Signaling 17 (820), eabg8145, 2024 | 2 | 2024 |
The septin modifier, forchlorfenuron, activates NLRP3 via a potassium-independent mitochondrial axis CL Holley, S Emming, MM Monteleone, M Mellacheruvu, KM Kenney, ... Cell Chemical Biology 31 (5), 962-972. e4, 2024 | | 2024 |
Fluorochrome-labeled inhibitors of caspase-1 require membrane permeabilization to efficiently access caspase-1 in macrophages. SJ Thygesen, SS Burgener, P Mudai, M Monteleone, D Boucher, ... European Journal of Immunology, e2350515-e2350515, 2024 | | 2024 |
Cytosolic Clade B Serpins, Serpinb1a, Serpinb6a and Serpinb9a Regulate Granule Serine Protease-induced Cell Death and Inflammation in Myeloid Cells by Cooperative and Distinct … SS Burgener Faculty of Medicine of the University of Bern, 2017 | | 2017 |
Activity and long-term stability of self-assembling enzymatic surface coatings S Burgener, U Pieles, J Köser European Cells and Materials 22 (SUPPL. 4), 21-21, 2011 | | 2011 |