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Shengwu Liu
Shengwu Liu
Instructor at Dana Farber Cancer Institute
Verified email at dfci.harvard.edu
Title
Cited by
Cited by
Year
Acquired Resistance to KRASG12C Inhibition in Cancer
MM Awad, S Liu, II Rybkin, KC Arbour, J Dilly, VW Zhu, ML Johnson, ...
New England Journal of Medicine 384 (25), 2382-2393, 2021
5292021
Mechanisms and clinical activity of an EGFR and HER2 exon 20–selective kinase inhibitor in non–small cell lung cancer
JP Robichaux, YY Elamin, Z Tan, BW Carter, S Zhang, S Liu, S Li, T Chen, ...
Nature medicine 24 (5), 638-646, 2018
4322018
Recruitment of Grb2 and SHIP1 by the ITT-like motif of TIGIT suppresses granule polarization and cytotoxicity of NK cells
S Liu, H Zhang, M Li, D Hu, C Li, B Ge, B Jin, Z Fan
Cell Death & Differentiation 20 (3), 456-464, 2013
3092013
Prostate cancer–associated SPOP mutations confer resistance to BET inhibitors through stabilization of BRD4
X Dai, W Gan, X Li, S Wang, W Zhang, L Huang, S Liu, Q Zhong, J Guo, ...
Nature medicine 23 (9), 1063-1071, 2017
2762017
T-cell immunoglobulin and ITIM domain (TIGIT) receptor/poliovirus receptor (PVR) ligand engagement suppresses interferon-γ production of natural killer cells via β-arrestin 2 …
M Li, P Xia, Y Du, S Liu, G Huang, J Chen, H Zhang, N Hou, X Cheng, ...
Journal of Biological Chemistry 289 (25), 17647-17657, 2014
2392014
Synergistic Immunostimulatory Effects and Therapeutic Benefit of Combined Histone Deacetylase and Bromodomain Inhibition in Non-small Cell Lung Cancer
WKK Adeegbe D, Liu Y, Lizotte PH, Kamihara Y, Aref AR, Almonte C, Dries R ...
Cancer Discov., 2017
1372017
Targeting HER2 Aberrations in Non–Small Cell Lung Cancer with Osimertinib
S Liu, S Li, J Hai, X Wang, T Chen, MM Quinn, P Gao, Y Zhang, H Ji, ...
Clinical Cancer Research 24 (11), 2594-2604, 2018
1282018
Mobocertinib (TAK-788): A Targeted Inhibitor of EGFR Exon 20 Insertion Mutants in Non–Small Cell Lung Cancer
F Gonzalvez, S Vincent, TE Baker, AE Gould, S Li, SD Wardwell, ...
Cancer discovery 11 (7), 1672-1687, 2021
1222021
BET Bromodomain Inhibition Cooperates with PD-1 Blockade to Facilitate Antitumor Response in Kras-Mutant Non–Small Cell Lung Cancer
DO Adeegbe, S Liu, MM Hattersley, M Bowden, CW Zhou, S Li, R Vlahos, ...
Cancer immunology research 6 (10), 1234-1245, 2018
912018
Assessing Therapeutic Efficacy of MEK Inhibition in a KRASG12C-Driven Mouse Model of Lung Cancer
S Li, S Liu, J Deng, EA Akbay, J Hai, C Ambrogio, L Zhang, F Zhou, ...
Clinical Cancer Research 24 (19), 4854-4864, 2018
602018
Cleavage of survivin by Granzyme M triggers degradation of the survivin-X-linked inhibitor of apoptosis protein (XIAP) complex to free caspase activity leading to cytolysis of …
D Hu, S Liu, L Shi, C Li, L Wu, Z Fan
Journal of biological chemistry 285 (24), 18326-18335, 2010
532010
Identification of SERPINB1 as a physiological inhibitor of human granzyme H
L Wang, Q Li, L Wu, S Liu, Y Zhang, X Yang, P Zhu, H Zhang, K Zhang, ...
The Journal of Immunology 190 (3), 1319-1330, 2013
482013
PS341 inhibits hepatocellular and colorectal cancer cells through the FOXO3/CTNNB1 signaling pathway
Z Yang, S Liu, M Zhu, H Zhang, J Wang, Q Xu, K Lin, X Zhou, M Tao, C Li, ...
Scientific reports 6 (1), 22090, 2016
442016
Synergy of WEE1 and mTOR Inhibition in Mutant KRAS-Driven Lung Cancers
J Hai, S Liu, L Bufe, K Do, T Chen, X Wang, C Ng, S Li, MS Tsao, ...
Clinical Cancer Research 23 (22), 6993-7005, 2017
392017
NK cells mediate synergistic antitumor effects of combined inhibition of HDAC6 and BET in a SCLC preclinical model
Y Liu, Y Li, S Liu, DO Adeegbe, CL Christensen, MM Quinn, R Dries, ...
Cancer research 78 (13), 3709-3717, 2018
382018
CD54-NOTCH1 axis controls tumor initiation and cancer stem cell functions in human prostate cancer
C Li, S Liu, R Yan, N Han, KK Wong, L Li
Theranostics 7 (1), 67, 2017
382017
Targeting HER2 Exon 20 Insertion–Mutant Lung Adenocarcinoma with a Novel Tyrosine Kinase Inhibitor Mobocertinib
H Han, S Li, T Chen, M Fitzgerald, S Liu, C Peng, KH Tang, S Cao, ...
Cancer research 81 (20), 5311-5324, 2021
362021
Use of ExVivo Patient-Derived Tumor Organotypic Spheroids to Identify Combination Therapies for HER2 Mutant Non–Small Cell Lung Cancer
E Ivanova, M Kuraguchi, M Xu, AJ Portell, L Taus, I Diala, AS Lalani, ...
Clinical Cancer Research 26 (10), 2393-2403, 2020
302020
Structural insights into the substrate specificity of human granzyme H: the functional roles of a novel RKR motif
L Wang, K Zhang, L Wu, S Liu, H Zhang, Q Zhou, L Tong, F Sun, Z Fan
The Journal of Immunology 188 (2), 765-773, 2012
242012
Mechanisms of acquired resistance to KRAS G12C inhibition in cancer.
M Awad, S Liu, K Arbour, V Zhu, M Johnson, R Heist, T Patil, G Riely, ...
Cancer Research 81 (13), 2021
92021
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