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Elena Bianchetti
Elena Bianchetti
LEXEO therapeutics
Verified email at columbia.edu
Title
Cited by
Cited by
Year
Induction of synthetic lethality in IDH1-mutated gliomas through inhibition of Bcl-xL
G Karpel-Massler, CT Ishida, E Bianchetti, Y Zhang, C Shu, T Tsujiuchi, ...
Nature communications 8 (1), 1-14, 2017
912017
Inhibition of Mitochondrial Matrix Chaperones and Antiapoptotic Bcl-2 Family Proteins Empower Antitumor Therapeutic ResponsesBcl-2 and Mitochondrial Chaperone Inhibition for …
G Karpel-Massler, CT Ishida, E Bianchetti, C Shu, R Perez-Lorenzo, ...
Cancer research 77 (13), 3513-3526, 2017
542017
Metabolic Reprogramming by Dual AKT/ERK Inhibition through Imipridones Elicits Unique Vulnerabilities in Glioblastomac-myc Levels Predict Therapeutic Responses to Imipridones
CT Ishida, Y Zhang, E Bianchetti, C Shu, TTT Nguyen, G Kleiner, ...
Clinical Cancer Research 24 (21), 5392-5406, 2018
502018
HDAC inhibitors elicit metabolic reprogramming by targeting super-enhancers in glioblastoma models
TTT Nguyen, Y Zhang, E Shang, C Shu, C Torrini, J Zhao, E Bianchetti, ...
The Journal of clinical investigation 130 (7), 3699-3716, 2020
442020
BH3-mimetics and BET-inhibitors elicit enhanced lethality in malignant glioma.
SMD Ishida CT, Bianchetti E, Shu C, Halatsch ME, Westhoff MA, Karpel-Massler G
Oncotarget, 2017
412017
Combined HDAC and Bromodomain Protein Inhibition Reprograms Tumor Cell Metabolism and Elicits Synthetic Lethality in GlioblastomaTargeting the Epigenome Reprograms Glioblastoma …
Y Zhang, CT Ishida, W Ishida, SFL Lo, J Zhao, C Shu, E Bianchetti, ...
Clinical Cancer Research 24 (16), 3941-3954, 2018
332018
ATF3 is a novel nuclear marker for migrating ependymal stem cells in the rat spinal cord
M Mladinic, E Bianchetti, A Dekanic, GL Mazzone, A Nistri
Stem cell research 12 (3), 815-827, 2014
312014
Stasimon contributes to the loss of sensory synapses and motor neuron death in a mouse model of spinal muscular atrophy
CM Simon, M Van Alstyne, F Lotti, E Bianchetti, S Tisdale, DM Watterson, ...
Cell reports 29 (12), 3885-3901. e5, 2019
272019
Mechanisms underlying cell death in ischemia-like damage to the rat spinal cord in vitro
E Bianchetti, M Mladinic, A Nistri
Cell death & disease 4 (7), e707-e707, 2013
242013
MET Inhibition Elicits PGC1α-Dependent Metabolic Reprogramming in GlioblastomaAcute and Chronic MET Inhibition Drives Oxidative Metabolism
Y Zhang, TTT Nguyen, E Shang, A Mela, N Humala, A Mahajan, J Zhao, ...
Cancer research 80 (1), 30-43, 2020
222020
Activation of LXR β inhibits tumor respiration and is synthetically lethal with Bcl‐xL inhibition
TTT Nguyen, CT Ishida, E Shang, C Shu, C Torrini, Y Zhang, E Bianchetti, ...
EMBO molecular medicine 11 (10), e10769, 2019
192019
Role of HSP70 in motoneuron survival after excitotoxic stress in a rat spinal cord injury model in vitro
A Shabbir, E Bianchetti, R Cargonja, A Petrovic, M Mladinic, K Pilipović, ...
European Journal of Neuroscience 42 (12), 3054-3065, 2015
182015
The volatile anesthetic methoxyflurane protects motoneurons against excitotoxicity in an in vitro model of rat spinal cord injury
A Shabbir, E Bianchetti, A Nistri
Neuroscience 285, 269-280, 2015
172015
Unusual increase in lumbar network excitability of the rat spinal cord evoked by the PARP-1 inhibitor PJ-34 through inhibition of glutamate uptake
SE Nasrabady, A Kuzhandaivel, A Akrami, E Bianchetti, M Milanese, ...
Neuropharmacology 63 (3), 415-426, 2012
172012
Activation of LXR receptors and inhibition of TRAP1 causes synthetic lethality in solid tumors
TTT Nguyen, CT Ishida, E Shang, C Shu, E Bianchetti, G Karpel-Massler, ...
Cancers 11 (6), 788, 2019
142019
Usp9X regulates cell death in malignant peripheral nerve sheath tumors
E Bianchetti, SJ Bates, SL Carroll, MD Siegelin, KA Roth
Scientific reports 8 (1), 1-12, 2018
92018
Dual Inhibition of Bcl-2/Bcl-xL and XPO1 is synthetically lethal in glioblastoma model systems
E Shang, Y Zhang, C Shu, CT Ishida, E Bianchetti, MA Westhoff, ...
Scientific reports 8 (1), 1-11, 2018
72018
Inhibition of Bcl-2/Bcl-xL and c-MET causes synthetic lethality in model systems of glioblastoma
Y Zhang, CT Ishida, C Shu, G Kleiner, MJ Sanchez-Quintero, E Bianchetti, ...
Scientific reports 8 (1), 1-12, 2018
72018
BH3-mimetics and BET-inhibitors elicit enhanced lethality in malignant glioma. Oncotarget 8, 29558–29573
CT Ishida, E Bianchetti, C Shu, ME Halatsch, MA Westhoff, ...
62017
RAB38 Facilitates Energy Metabolism and Counteracts Cell Death in Glioblastoma Cells
E Bianchetti, SJ Bates, TTT Nguyen, MD Siegelin, KA Roth
Cells 10 (7), 1643, 2021
12021
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