Donor and host photoreceptors engage in material transfer following transplantation of post-mitotic photoreceptor precursors RA Pearson, A Gonzalez-Cordero, EL West, JR Ribeiro, N Aghaizu, ... Nature communications 7 (1), 13029, 2016 | 300 | 2016 |
Recapitulation of human retinal development from human pluripotent stem cells generates transplantable populations of cone photoreceptors A Gonzalez-Cordero, K Kruczek, A Naeem, M Fernando, M Kloc, J Ribeiro, ... Stem cell reports 9 (3), 820-837, 2017 | 226 | 2017 |
Transplanted donor-or stem cell-derived cone photoreceptors can both integrate and undergo material transfer in an environment-dependent manner PV Waldron, F Di Marco, K Kruczek, J Ribeiro, AB Graca, C Hippert, ... Stem cell reports 10 (2), 406-421, 2018 | 104 | 2018 |
Isolation and comparative transcriptome analysis of human fetal and iPSC-derived cone photoreceptor cells E Welby, J Lakowski, V Di Foggia, D Budinger, A Gonzalez-Cordero, ... Stem Cell Reports 9 (6), 1898-1915, 2017 | 103 | 2017 |
Pluripotent stem cell-derived retinal organoids for disease modeling and development of therapies K Kruczek, A Swaroop Stem Cells 38 (10), 1206-1215, 2020 | 100 | 2020 |
Differentiation and transplantation of embryonic stem cell-derived cone photoreceptors into a mouse model of end-stage retinal degeneration K Kruczek, A Gonzalez-Cordero, D Goh, A Naeem, M Jonikas, ... Stem cell reports 8 (6), 1659-1674, 2017 | 93 | 2017 |
Transcriptome-based molecular staging of human stem cell-derived retinal organoids uncovers accelerated photoreceptor differentiation by 9-cis retinal KD Kaya, HY Chen, MJ Brooks, RA Kelley, H Shimada, K Nagashima, ... Molecular vision 25, 663, 2019 | 68 | 2019 |
Assessment of AAV vector tropisms for mouse and human pluripotent stem cell–derived RPE and photoreceptor cells A Gonzalez-Cordero, D Goh, K Kruczek, A Naeem, M Fernando, ... Human gene therapy 29 (10), 1124-1139, 2018 | 65 | 2018 |
Gene therapy of dominant CRX-Leber congenital amaurosis using patient stem cell-derived retinal organoids K Kruczek, Z Qu, J Gentry, BR Fadl, L Gieser, S Hiriyanna, Z Batz, ... Stem Cell Reports 16 (2), 252-263, 2021 | 54 | 2021 |
Pou2f1 and Pou2f2 cooperate to control the timing of cone photoreceptor production in the developing mouse retina A Javed, P Mattar, S Lu, K Kruczek, M Kloc, A Gonzalez-Cordero, ... Development 147 (18), dev188730, 2020 | 48 | 2020 |
Pluripotent stem cells and their utility in treating photoreceptor degenerations ND Aghaizu, K Kruczek, A Gonzalez-Cordero, RR Ali, RA Pearson Progress in brain research 231, 191-223, 2017 | 29 | 2017 |
Soy protein nanofiber scaffolds for uniform maturation of human induced pluripotent stem cell-derived retinal pigment epithelium MA Phelan, K Kruczek, JH Wilson, MJ Brooks, CT Drinnan, F Regent, ... Tissue Engineering Part C: Methods 26 (8), 433-446, 2020 | 21 | 2020 |
In vitro modeling and rescue of ciliopathy associated with IQCB1/NPHP5 mutations using patient-derived cells K Kruczek, Z Qu, E Welby, H Shimada, S Hiriyanna, MA English, WM Zein, ... Stem Cell Reports 17 (10), 2172-2186, 2022 | 11 | 2022 |
Patient stem cell-derived in vitro disease models for developing novel therapies of retinal ciliopathies. K Kruczek, A Swaroop Current Topics in Developmental Biology 155, 127-163, 2023 | | 2023 |
Gene therapy for treatment of crx-autosomal dominant retinopathies A Swaroop, Z Wu, SD Hiriyanna, K Kruczek US Patent App. 17/789,729, 2023 | | 2023 |
Using patient iPSC-derived retinal organoids to identify mechanism underlying inherited blindness caused by mutations in the NPHP5 gene Z Qu, E Welby, K Kruczek, B Fadl, F Regent, H Shimada, M English, ... Investigative Ophthalmology & Visual Science 61 (7), 3810-3810, 2020 | | 2020 |
Transcriptional regulation of cone photoreceptor development M Cayouette, A Javed, P Mattar, K Kruczek, S Lu, M Kloc, ... IBRO Reports 6, S20-S21, 2019 | | 2019 |
Differentiation and transplantation of mouse embryonic stem cell-derived cone photoreceptor precursors K Kruczek UCL (University College London), 2017 | | 2017 |
Generation and transplantation of human pluripotent stem cell derived cone photoreceptors into models of retinal degeneration A Gonzalez-Cordero, K Kruczek, A Naeem, M Fernando, M Kloc, D Goh, ... Conference on Changing the Face of Modern Medicine-Stem Cells and Gene Therapy, 2016 | | 2016 |
Isolating and characterising human cone photoreceptors for cell therapy E Welby, V Di Foggia, J Lakowski, D Budinger, K Kruczek, M Hubank, ... Conference on Changing the Face of Modern Medicine-Stem Cells and Gene Therapy, 2016 | | 2016 |