| AAV-CRISPR gene editing is negated by pre-existing immunity to Cas9 A Li, MR Tanner, CM Lee, AE Hurley, M De Giorgi, KE Jarrett, TH Davis, ... Molecular Therapy 28 (6), 1432-1441, 2020 | 171 | 2020 |
| A self-deleting AAV-CRISPR system for in vivo genome editing A Li, CM Lee, AE Hurley, KE Jarrett, M De Giorgi, W Lu, KS Balderrama, ... Molecular Therapy-Methods & Clinical Development 12, 111-122, 2018 | 126 | 2018 |
| Somatic Editing of Ldlr With Adeno-Associated Viral-CRISPR Is an Efficient Tool for Atherosclerosis Research KE Jarrett, C Lee, M De Giorgi, A Hurley, BK Gillard, AM Doerfler, A Li, ... Arteriosclerosis, thrombosis, and vascular biology 38 (9), 1997-2006, 2018 | 75 | 2018 |
| TFEB regulates murine liver cell fate during development and regeneration N Pastore, T Huynh, NJ Herz, A Calcagni’, TJ Klisch, L Brunetti, KH Kim, ... Nature communications 11 (1), 2461, 2020 | 40 | 2020 |
| Depletion of essential isoprenoids and ER stress induction following acute liver-specific deletion of HMG-CoA reductase M De Giorgi, KE Jarrett, JC Burton, AM Doerfler, A Hurley, A Li, RH Hsu, ... Journal of lipid research 61 (12), 1675-1686, 2020 | 19 | 2020 |
| Use of synthetic urine as a matrix substitute for standard and quality control materials in the clinical assessment of iodine by inductively coupled plasma mass spectrometry CJ Haglock-Adler, A Hurley, FG Strathmann Clinical Biochemistry 47 (15), 80-82, 2014 | 19 | 2014 |
| In vivo genome editing at the albumin locus to treat methylmalonic acidemia JL Schneller, CM Lee, LE Venturoni, RJ Chandler, A Li, S Myung, ... Molecular Therapy-Methods & Clinical Development 23, 619-632, 2021 | 12 | 2021 |
| Targeting the Apoa1 locus for liver-directed gene therapy M De Giorgi, A Li, A Hurley, M Barzi, AM Doerfler, NA Cherayil, HE Smith, ... Molecular Therapy Methods & Clinical Development 21, 656-669, 2021 | 12 | 2021 |
| LPA disruption with AAV-CRISPR potently lowers plasma apo (a) in transgenic mouse model: A proof-of-concept study AM Doerfler, SH Park, JM Assini, A Youssef, L Saxena, AB Yaseen, ... Molecular Therapy-Methods & Clinical Development 27, 337-351, 2022 | 11 | 2022 |
| Highly conserved amino acid residues in apolipoprotein A1 discordantly induce high density lipoprotein assembly in vitro and in vivo D Yelamanchili, J Liu, AM Gotto Jr, AE Hurley, WR Lagor, BK Gillard, ... Biochimica et Biophysica Acta (BBA)-Molecular and Cell Biology of Lipids …, 2020 | 3 | 2020 |
| Speg interactions that regulate the stability of excitation-contraction coupling protein complexes in triads and dyads CS Lee, SY Jung, RSZ Yee, NH Agha, J Hong, T Chang, LW Babcock, ... Communications Biology 6 (1), 942, 2023 | 2 | 2023 |
| In vivo expansion of gene-targeted hepatocytes through transient inhibition of an essential gene M De Giorgi, SH Park, A Castoreno, M Cao, A Hurley, L Saxena, ... bioRxiv, 2023 | 2 | 2023 |
| Intestinal deletion of 3-Hydroxy-3-Methylglutaryl-Coenzyme A Reductase promotes expansion of the resident stem cell compartment AM Doerfler, J Han, KE Jarrett, L Tang, A Jain, A Saltzman, M De Giorgi, ... Arteriosclerosis, thrombosis, and vascular biology 42 (4), 381-394, 2022 | 1 | 2022 |
| In vivo Genome Editing to Treat Methylmalonic Acidemia (MMA) Caused by Methylmalonyl-CoA Mutase Deficiency (hMUT) JL Schneller, CM Lee, A Li, TJ Cradick, RJ Chandler, AE Hurley, ... MOLECULAR THERAPY 27 (4), 369-369, 2019 | 1 | 2019 |
| Encapsulation of AAVs into protein vault nanoparticles as a novel solution to gene therapy’s neutralizing antibody problem LT Collins, W Beatty, B Moyo, M Alves-Bezerra, A Hurley, Q Lou, ZH Zhou, ... bioRxiv, 2023.11. 29.569229, 2023 | | 2023 |
| Adeno-Associated virus 8 delivers an immunomodulatory peptide to mouse liver more efficiently than to rat liver Y Wang, A Hurley, M De Giorgi, MR Tanner, RC Hu, MW Pennington, ... Plos one 18 (4), e0283996, 2023 | | 2023 |
| Deletion of 3-Hydroxy-3-Methylglutaryl-Coenzyme A Reductase Promotes Expansion of the Resident Stem Cell Compartment A Doerfler, J Han, K Jarrett, L Tang, A Jain, A Saltzman, M De Giorgi, ... Health Research Alliance, 2023 | | 2023 |
| Selective expansion of gene-targeted cells W Lagor, A Hurley, K Jarrett, KD Bissing, M De Giorgi, M Furgurson US Patent App. 17/756,242, 2023 | | 2023 |
| Genetic Inhibition Of Hepatic Dolichol Biosynthesis Results In Hypolipidemia M De Giorgi, AM Doerfler, A Hurley, C Walkey, WR Lagor Arteriosclerosis, Thrombosis, and Vascular Biology 42 (Suppl_1), A425-A425, 2022 | | 2022 |
| In Vivo Expansion of Gene-Targeted Hepatocytes Through Inhibition of an Essential Gene M De Giorgi, A Hurley, AM Doerfler, MN Furgurson, MA Chuecos, S Hyde, ... MOLECULAR THERAPY 30 (4), 568-569, 2022 | | 2022 |
William R. LagorProfessor, Baylor College of MedicineVerified email at bcm.edu
