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Samuel A Sances
Samuel A Sances
Verified email at cshs.org
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Year
Human iPSC-derived blood-brain barrier chips enable disease modeling and personalized medicine applications
GD Vatine, R Barrile, MJ Workman, S Sances, BK Barriga, M Rahnama, ...
Cell stem cell 24 (6), 995-1005. e6, 2019
4482019
Modeling ALS with motor neurons derived from human induced pluripotent stem cells
S Sances, LI Bruijn, S Chandran, K Eggan, R Ho, JR Klim, MR Livesey, ...
Nature neuroscience 19 (4), 542-553, 2016
3022016
Multi-lineage human iPSC-derived platforms for disease modeling and drug discovery
A Sharma, S Sances, MJ Workman, CN Svendsen
Cell stem cell 26 (3), 309-329, 2020
2042020
Human iPSC-derived endothelial cells and microengineered organ-chip enhance neuronal development
S Sances, R Ho, G Vatine, D West, A Laperle, A Meyer, M Godoy, PS Kay, ...
Stem cell reports 10 (4), 1222-1236, 2018
1472018
iPSC modeling of young-onset Parkinson’s disease reveals a molecular signature of disease and novel therapeutic candidates
AH Laperle, S Sances, N Yucer, VJ Dardov, VJ Garcia, R Ho, AN Fulton, ...
Nature medicine 26 (2), 289-299, 2020
1112020
ALS disrupts spinal motor neuron maturation and aging pathways within gene co-expression networks
R Ho, S Sances, G Gowing, MW Amoroso, JG O'Rourke, A Sahabian, ...
Nature neuroscience 19 (9), 1256-1267, 2016
1082016
Brain-on-a-chip: Recent advances in design and techniques for microfluidic models of the brain in health and disease
L Amirifar, A Shamloo, R Nasiri, NR de Barros, ZZ Wang, BD Unluturk, ...
Biomaterials 285, 121531, 2022
542022
Organoid and organ-on-a-chip systems: new paradigms for modeling neurological and gastrointestinal disease
AA Akhtar, S Sances, R Barrett, JJ Breunig
Current stem cell reports 3, 98-111, 2017
252017
Development of spinal cord on a microfluidic chip
SJ Kerns, N Wen, C Lucchesi, CD Hinojosa, J Fraser, G Hamilton, ...
US Patent App. 16/286,185, 2019
62019
Tissue clearing of human iPSC-derived organ-chips enables high resolution imaging and analysis
BN Ondatje, S Sances, MJ Workman, CN Svendsen
Lab on a Chip 22 (21), 4246-4255, 2022
52022
Microfluidic model of the blood brain barrier
SJ Kerns, N Wen, C Lucchesi, CD Hinojosa, J Fraser, G Hamilton, ...
US Patent App. 15/768,736, 2018
52018
Microfluidic Model of the Blood Brain Barrier
SJ Kerns, N Wen, C Lucchesi, CD Hinojosa, J Fraser, G Hamilton, ...
US Patent App. 15/955,383, 2018
52018
Human pluripotent stem cell derived neurodegenerative disease models on a microfluidic chip
S Sances, A Laperle, N Yucer, CN Svendsen
US Patent App. 17/041,672, 2021
42021
Diagnostic and drug screening for molecular signatures of early onset sporadic parkinson's disease
A Laperle, S Sances, N Yucer, CN Svendsen
US Patent App. 17/043,272, 2021
42021
Pkc pathway in parkinson's disease
A Laperle, S Sances, N Yucer, CN Svendsen
US Patent App. 17/043,344, 2021
42021
Novel differentiation technique to generate dopaminergic neurons from induced pluripotent stem cells
A Laperle, S Sances, N Yucer, CN Svendsen
US Patent App. 17/041,788, 2021
32021
Multi-lineage cardiovascular microfluidic organ-chip
A Sharma, S Sances, C Svendsen
US Patent App. 17/921,217, 2023
22023
Differential Vulnerability and Response to Injury Among Brain Cell Types Comprising the Neurovascular Unit
P Rajput, A Brookshier, S Kothari, L Eckstein, H Chang, S Liska, J Lamb, ...
Journal of Neuroscience, 2024
2024
Deep Learning Analysis on Images of iPSC-derived Motor Neurons Carrying fALS-genetics Reveals Disease-Relevant Phenotypes
R Atmaramani, T Dreossi, K Ford, L Gan, J Mitchell, S Tu, J Velayutham, ...
bioRxiv, 2024.01. 04.574270, 2024
2024
Multi-lineage heart-chip models drug cardiotoxicity and enhances maturation of human stem cell-derived cardiovascular cells
M Mozneb, A Jenkins, S Sances, S Pohlman, MJ Workman, D West, ...
Lab on a Chip 24 (4), 869-881, 2024
2024
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