Deregulated hepsin protease activity confers oncogenicity by concomitantly augmenting HGF/MET signalling and disrupting epithelial cohesion TA Tervonen, D Belitškin, SM Pant, JI Englund, E Marques, ... Oncogene 35 (14), 1832-1846, 2016 | 48 | 2016 |
MITI minimum information guidelines for highly multiplexed tissue images D Schapiro, C Yapp, A Sokolov, SM Reynolds, YA Chen, D Sudar, Y Xie, ... Nature methods 19 (3), 262-267, 2022 | 43 | 2022 |
Design, synthesis, and testing of potent, selective hepsin inhibitors via application of an automated closed-loop optimization platform SM Pant, A Mukonoweshuro, B Desai, MK Ramjee, CN Selway, GJ Tarver, ... Journal of medicinal chemistry 61 (10), 4335-4347, 2018 | 34 | 2018 |
Discovery of selective matriptase and hepsin serine protease inhibitors: useful chemical tools for cancer cell biology VC Damalanka, Z Han, P Karmakar, AJ O’Donoghue, F La Greca, T Kim, ... Journal of medicinal chemistry 62 (2), 480-490, 2018 | 29 | 2018 |
Hepsin regulates TGFβ signaling via fibronectin proteolysis D Belitškin, SM Pant, P Munne, I Suleymanova, K Belitškina, HA Hongisto, ... EMBO reports 22 (11), e52532, 2021 | 12 | 2021 |
Oncogenic Ras disrupts epithelial integrity by activating the transmembrane serine protease hepsin TA Tervonen, SM Pant, D Belitškin, JI Englund, K Närhi, C Haglund, ... Cancer Research 81 (6), 1513-1527, 2021 | 11 | 2021 |
Analyzing the type II transmembrane serine protease hepsin-dependent basement membrane remodeling in 3D cell culture SM Pant, D Belitskin, H Ala-Hongisto, J Klefström, TA Tervonen Proteases and Cancer: Methods and Protocols, 169-178, 2018 | 9 | 2018 |
Resident memory T cell development is associated with AP-1 transcription factor upregulation across anatomical niches. NP Smith, Y Yan, Y Pan, JB Williams, K Manakongtreecheep, S Pant, ... bioRxiv, 2023.09. 29.560006, 2023 | 3 | 2023 |
Hepsin promotes breast tumor growth signaling via the TGFβ‐EGFR axis D Belitškin, P Munne, SM Pant, JM Anttila, I Suleymanova, K Belitškina, ... Molecular oncology 18 (3), 547-561, 2024 | 2 | 2024 |
Cell state dependent effects of Bmal1 on melanoma immunity and tumorigenicity X Zhang, SM Pant, CC Ritch, HY Tang, H Shao, H Dweep, YY Gong, ... Nature communications 15 (1), 633, 2024 | 1 | 2024 |
Spatial multi-omics profiling of tumor cell phenotypes in primary cutaneous melanoma at single-cell resolution T Vallius, E Novikov, AN Johnson, S Yingxiao, R Pelletier, S Pant, ... Cancer Research 84 (6_Supplement), 2593-2593, 2024 | | 2024 |
LKB1 overcomes RAS pathway-mediated loss of epithelial integrity TA Tervonen, SM Pant, J Englund, J Klefström Cancer Research 83 (7_Supplement), 5817-5817, 2023 | | 2023 |
Hepsin promotes breast tumor growth signaling via TGF beta-EGFR axis T Tervonen, D Belitskin, P Munne, S Pant, J Anttila, K Belitskina, ... European Journal of Cancer 174, S98, 2022 | | 2022 |
Serine protease hepsin regulates tumor growth via TGFbeta-EGFR signaling axis TA Tervonen, D Belitškin, P Munne, SM Pant, I Suleymanova, K Belitškina, ... Cancer Research 82 (12_Supplement), 834-834, 2022 | | 2022 |
Role of Serine Protease Hepsin in Breast Cancer SM Pant Helsingin yliopisto, 2021 | | 2021 |
Research Collaborations: A guide for early career researchers by early career researchers E Woollen, S Shinton, S Thomas Institute for Academic Development, The University of Edinburgh, 2019 | | 2019 |
The Cell‐Surface, Transmembrane Serine Protease Hepsin: Discovery, Function and Role in Cancer D Belitškin, SM Pant, T Tervonen, J Klefström Extracellular Targeting of Cell Signaling in Cancer: Strategies Directed at …, 2018 | | 2018 |