| Design, synthesis and biological evaluation of novel imidazo [4, 5-c] pyridinecarboxamide derivatives as PARP-1 inhibitors Q Zhu, X Wang, Z Chu, G He, G Dong, Y Xu Bioorganic & medicinal chemistry letters 23 (7), 1993-1996, 2013 | 39 | 2013 |
| Discovery of bisubstrate inhibitors for protein N-terminal methyltransferase 1 D Chen, G Dong, N Noinaj, R Huang Journal of medicinal chemistry 62 (7), 3773-3779, 2019 | 26 | 2019 |
| Probing the plasticity in the active site of protein N-terminal methyltransferase 1 using bisubstrate analogues D Chen, C Dong, G Dong, K Srinivasan, J Min, N Noinaj, R Huang Journal of medicinal chemistry 63 (15), 8419-8431, 2020 | 21 | 2020 |
| An asparagine/glycine switch governs product specificity of human N-terminal methyltransferase NTMT2 C Dong, G Dong, L Li, L Zhu, W Tempel, Y Liu, R Huang, J Min Communications Biology 1 (1), 183, 2018 | 20 | 2018 |
| Discovery of a potent and dual-selective bisubstrate inhibitor for protein arginine methyltransferase 4/5 AA Al-Hamashi, D Chen, Y Deng, G Dong, R Huang Acta Pharmaceutica Sinica B 11 (9), 2709-2718, 2021 | 15 | 2021 |
| Optimization of high-throughput methyltransferase assays for the discovery of small molecule inhibitors G Dong, A Yasgar, DL Peterson, A Zakharov, D Talley, KCC Cheng, ... ACS combinatorial science 22 (8), 422-432, 2020 | 15 | 2020 |
| Selective peptidomimetic inhibitors of NTMT1/2: rational design, synthesis, characterization, and crystallographic studies BD Mackie, D Chen, G Dong, C Dong, H Parker, CE Schaner Tooley, ... Journal of medicinal chemistry 63 (17), 9512-9522, 2020 | 14 | 2020 |
| Structure-based discovery of cell-potent peptidomimetic inhibitors for protein N-terminal methyltransferase 1 D Chen, G Dong, Y Deng, N Noinaj, R Huang ACS Medicinal Chemistry Letters 12 (3), 485-493, 2021 | 10 | 2021 |
| Improved cell-potent and selective peptidomimetic inhibitors of protein N-terminal methyltransferase 1 G Dong, ID Iyamu, JZ Vilseck, D Chen, R Huang Molecules 27 (4), 1381, 2022 | 6 | 2022 |
| Structure–activity relationship studies of Venglustat on NTMT1 inhibition Y Deng, G Dong, Y Meng, N Noinaj, R Huang Journal of Medicinal Chemistry 66 (2), 1601-1615, 2023 | 4 | 2023 |
| Venglustat inhibits protein N-terminal methyltransferase 1 in a substrate-competitive manner G Dong, Y Deng, A Yasgar, R Yadav, D Talley, AV Zakharov, S Jain, ... Journal of medicinal chemistry 65 (18), 12334-12345, 2022 | 3 | 2022 |
| PRODUCT SPECIFICITY AND INHIBITION OF PROTEIN N-TERMINAL METHYLTRANSFERASE 1/2 G Dong Purdue University Graduate School, 2021 | | 2021 |
| Inhibitors for protein n-terminal methyltransferase and uses thereof R Huang, D Chen, G Dong US Patent App. 16/414,024, 2019 | | 2019 |
| Deciphering the role of N‐terminal methylation in modulating yeast protein function including the multitasking stress response protein, Hsp31 P Chen, G Dong, T Hazbun, R Huang The FASEB Journal 33 (S1), 632.3-632.3, 2019 | | 2019 |
