Jason Shearer
Jason Shearer
Semmes Distinguished Professor of Chemistry, Trinity University
Verified email at - Homepage
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The Amyloid-β Peptide of Alzheimer’s Disease Binds CuI in a Linear Bis-His Coordination Environment: Insight into a Possible Neuroprotective Mechanism for the†…
J Shearer, VA Szalai
Journal of the American Chemical Society 130 (52), 17826-17835, 2008
Alkylation of nucleic acids by a model quinone methide
P Pande, J Shearer, J Yang, WA Greenberg, SE Rokita
Journal of the American Chemical Society 121 (29), 6773-6779, 1999
A nickel phosphine complex as a fast and efficient hydrogen production catalyst
L Gan, TL Groy, P Tarakeshwar, SKS Mazinani, J Shearer, V Mujica, ...
Journal of the American Chemical Society 137 (3), 1109-1115, 2015
Diversity, function and evolution of genes coding for putative Ni‐containing superoxide dismutases
CL Dupont, K Neupane, J Shearer, B Palenik
Environmental microbiology 10 (7), 1831-1843, 2008
Synthesis and reactivity of a mononuclear non-haem cobalt (IV)-oxo complex
B Wang, YM Lee, WY Tcho, S Tussupbayev, ST Kim, Y Kim, MS Seo, ...
Nature communications 8 (1), 1-10, 2017
Substrate Oxidation by Copper− Dioxygen Adducts: Mechanistic Considerations
J Shearer, CX Zhang, LN Zakharov, AL Rheingold, KD Karlin
Journal of the American Chemical Society 127 (15), 5469-5483, 2005
A nickel superoxide dismutase maquette that reproduces the spectroscopic and functional properties of the metalloenzyme
J Shearer, LM Long
Inorganic chemistry 45 (6), 2358-2360, 2006
Tuning Copper− Dioxygen Reactivity and Exogenous Substrate Oxidations via Alterations in Ligand Electronics
CX Zhang, HC Liang, E Kim, J Shearer, ME Helton, E Kim, S Kaderli, ...
Journal of the American Chemical Society 125 (3), 634-635, 2003
Synthetic Models for the Cysteinate-Ligated Non-Heme Iron Enzyme Superoxide Reductase:  Observation and Structural Characterization by XAS of an FeIII−OOH†…
J Shearer, RC Scarrow, JA Kovacs
Journal of the American Chemical Society 124 (39), 11709-11717, 2002
How do oxidized thiolate ligands affect the electronic and reactivity properties of a nitrile hydratase model compound?
I Kung, D Schweitzer, J Shearer, WD Taylor, HL Jackson, S Lovell, ...
Journal of the American Chemical Society 122 (34), 8299-8300, 2000
Probing variable axial ligation in nickel superoxide dismutase utilizing metallopeptide-based models: Insight into the superoxide disproportionation mechanism
KP Neupane, K Gearty, A Francis, J Shearer
Journal of the American Chemical Society 129 (47), 14605-14618, 2007
Why is there an “inert” metal center in the active site of nitrile hydratase? Reactivity and ligand dissociation from a five-coordinate Co (III) nitrile hydratase model
J Shearer, IY Kung, S Lovell, W Kaminsky, JA Kovacs
Journal of the American Chemical Society 123 (3), 463-468, 2001
Bisamidate and Mixed Amine/Amidate NiN2S2 Complexes as Models for Nickel-Containing Acetyl Coenzyme A Synthase and Superoxide Dismutase: An†…
V Mathrubootham, J Thomas, R Staples, J McCraken, J Shearer, EL Hegg
Inorganic chemistry 49 (12), 5393-5406, 2010
[Me4N](NiII(BEAAM)):  A Synthetic Model for Nickel Superoxide Dismutase That Contains Ni in a Mixed Amine/Amide Coordination Environment
J Shearer, N Zhao
Inorganic chemistry 45 (24), 9637-9639, 2006
Distinguishing Rate-Limiting Electron versus H-Atom Transfers in Cu2(O2)-Mediated Oxidative N-Dealkylations:  Application of Inter- versus Intramolecular†…
J Shearer, CX Zhang, LQ Hatcher, KD Karlin
Journal of the American Chemical Society 125 (42), 12670-12671, 2003
The influence of amine/amide versus bisamide coordination in nickel superoxide dismutase
KP Neupane, J Shearer
Inorganic chemistry 45 (26), 10552-10566, 2006
Phenol Nitration Induced by an {Fe(NO)2}10 Dinitrosyl Iron Complex
NG Tran, H Kalyvas, KM Skodje, T Hayashi, P MoŽnne-Loccoz, PE Callan, ...
Journal of the American Chemical Society 133 (5), 1184-1187, 2011
The first example of a nitrile hydratase model complex that reversibly binds nitriles
J Shearer, HL Jackson, D Schweitzer, DK Rittenberg, TM Leavy, ...
Journal of the American Chemical Society 124 (38), 11417-11428, 2002
A redox-active, compact molecule for cross-linking amyloidogenic peptides into nontoxic, off-pathway aggregates: In vitro and in vivo efficacy and molecular mechanisms
JS Derrick, RA Kerr, Y Nam, SB Oh, HJ Lee, KG Earnest, N Suh, KL Peck, ...
Journal of the American Chemical Society 137 (46), 14785-14797, 2015
Isolation of a (dinitrogen) tricopper (I) complex
LJ Murray, WW Weare, J Shearer, AD Mitchell, KA Abboud
Journal of the American Chemical Society 136 (39), 13502-13505, 2014
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